Comparison of laser in situ keratomileusis and photorefractive keratectomy results: Long-term follow-up

2008 ◽  
Vol 34 (9) ◽  
pp. 1527-1531 ◽  
Author(s):  
Takashi Miyai ◽  
Kazunori Miyata ◽  
Ryohei Nejima ◽  
Masato Honbo ◽  
Keiichiro Minami ◽  
...  
Keyword(s):  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy ◽  
Long Term Follow Up

Laser in situ keratomileusis application for myopia over minus 14 diopter with long-term follow-up

2012 ◽  
Vol 32 (5) ◽  
pp. 435-441 ◽  
Author(s):  
Faik Oruçoğlu ◽  
James D. Kingham ◽  
Mahir Kendüşim ◽  
Buket Ayoğlu ◽  
Berrin Toksu ◽  
...  
Keyword(s):  
Laser In Situ Keratomileusis ◽  
Long Term Follow Up

Femtosecond-assisted laser in situ keratomileusis for high myopia correction: Long-term follow-up outcomes.

2019 ◽  
Vol 30 (3) ◽  
pp. 446-454 ◽  
Author(s):  
Alfredo Vega-Estrada ◽  
Jorge L Alio
Keyword(s):  
Excimer Laser ◽  
Repetition Rate ◽  
High Myopia ◽  
Spherical Aberration ◽  
Pearson Correlation ◽  
Laser In Situ Keratomileusis ◽  
Long Term Follow Up

Objective: Report the outcomes of laser in situ keratomileusis (LASIK) for high myopia correction after long-term follow-up. Methods: Retrospective, consecutive, clinical study including 70 eyes that underwent LASIK using a 500 Hertz (Hz) repetition rate excimer laser and femtosecond technology for flap creation. Visual, refractive, corneal aberrations, and correlation among the variables were evaluated during 3 years. In addition, 34 eyes were followed during 5 years. Results: Significant improvement of 17 logMAR lines was observed in uncorrected vision at 5 years (p < 0.01). This was consistent with spherical equivalent reduction that came from mean preoperative –7.79 diopters (D) to 5 years postoperative –0.24 D (p < 0.01). Significant induction of primary spherical aberration and coma aberration was also found (p < 0.01) at 3 months with levels of 0.61 µm and 0.47 µm, respectively, with no further changes at 5 years (p > 0.05). Pearson correlation showed that the amount of high-order aberrations at 3 months postoperativeley was significantly correlated with the changes in the keratometry throughout the 5 years (delta K) (R2 0.242 p = 0.05). Finally, preoperative corneal asphericity showed an inverse correlation with the delta K (R2 –308 p = 0.01). Conclusions: Results from this study suggests that LASIK for high myopia correction using 500 Hz repetition rate excimer laser provides stable visual, refractive and aberrometric results after 5 years of follow-up. A more prolate cornea and the amount of higher-order aberrations induced after LASIK are factors that negatively impact in the long-term stability of the procedure.

scholarly journals Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3864
Author(s):  
Maximilian Gassenmaier ◽  
Matthias Hahn ◽  
Gisela Metzler ◽  
Jürgen Bauer ◽  
Amir Sadegh Yazdi ◽  
...  
Keyword(s):  
Prognostic Significance ◽  
Diagnostic Interpretation ◽  
Dysplastic Nevi ◽  
Melanocytic Tumors ◽  
Invasive Component ◽  
Uncertain Significance ◽  
Long Term Follow Up

Background: PReferentially expressed Antigen in MElanoma (PRAME) immunohistochemistry is increasingly used as diagnostic adjunct in the evaluation of melanocytic tumors. The expression and prognostic significance of PRAME in melanomas ≤1.0 mm and its diagnostic utility in the distinction from severely dysplastic compound nevi (SDN) have not been studied. Methods: We investigated and compared the immunohistochemical PRAME expression in 70 matched thin metastasizing and non-metastasizing melanomas and 45 nevi from patients with long-term follow-up (35 SDN and 10 unequivocally benign compound nevi). Results: Diffuse PRAME staining in >75% of lesional epidermal and dermal melanocytes identified 58.6% of thin melanomas but did not distinguish metastasizing from non-metastasizing melanomas (p = 0.81). A superficial atypical melanocytic proliferation of uncertain significance, in which the final diagnostic interpretation favored a SDN was the only nevus with diffuse PRAME expression (1/45). Melanomas and SDN with PRAME immunoreactivity exhibited different staining patterns. Most melanomas (67.6%) showed uniform PRAME expression in the in situ and invasive component, whereas most SDN (81.0%) showed a decreasing gradient with depth. Conclusion: Diffuse intraepidermal and dermal PRAME staining is highly specific for melanomas in the distinction from SDN. PRAME expression is not a prognostic biomarker in melanomas ≤1.0 mm.

Complications of long-term ventilation tubes

2013 ◽  
Vol 127 (5) ◽  
pp. 509-510 ◽  
Author(s):  
H Mohammed ◽  
P Martinez-Devesa
Keyword(s):  
Ventilation Tube ◽  
Material Degradation ◽  
Long Term Follow Up ◽  
Ventilation Tubes ◽  
Chronic Inflammatory Reaction ◽  
Materials Used ◽  
Long Term Ventilation

AbstractObjective:To demonstrate that ventilation tubes can remain in situ much longer than expected, and that the materials used in the manufacturing of these tubes can degrade and cause complications. Long-term follow up and replacement of the tube is recommended.Method:Case report and review of the literature concerning the use of long-term ventilation tubes.Results:In the case reported, the ventilation tube was in place for 19 years, which resulted in chronic ear discharge. When it was removed, it was noted that the tube itself had degraded and had caused a chronic inflammatory reaction.Conclusion:We recommend that the long-term use of ventilation tubes is followed up and that the tube is replaced before material degradation takes place.

Penile Melanoma In Situ: Long Term Follow Up

Urology ◽  
2020 ◽  
Vol 141 ◽  
pp. e51-e52
Author(s):  
Kevin Krughoff ◽  
Amichai Kilchevksy ◽  
Wayne Stadelmann ◽  
Timothy Gorman ◽  
Ramiro Madden-Fuentes
Keyword(s):  
Melanoma In Situ ◽  
Long Term Follow Up
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