Effectiveness of professional fluorides against enamel white spot lesions during fixed orthodontic treatment: A systematic review and meta-analysis

2019 ◽  
Vol 82 ◽  
pp. 1-10 ◽  
Author(s):  
Divesh Sardana ◽  
Jingyang Zhang ◽  
Manikandan Ekambaram ◽  
Yanqi Yang ◽  
Colman P. McGrath ◽  
...  
Keyword(s):  
Systematic Review ◽  
Orthodontic Treatment ◽  
Meta Analysis ◽  
White Spot ◽  
White Spot Lesions

scholarly journals Effect of Chlorhexidine Varnish and Fluoride Varnish on White Spot Lesions in Orthodontic Patients- a Systematic Review

2021 ◽  
Vol 15 (1) ◽  
pp. 151-159
Author(s):  
Aravinthrajkumar Govindaraj ◽  
S.P. Saravana Dinesh
Keyword(s):  
Systematic Review ◽  
Oral Hygiene ◽  
Orthodontic Treatment ◽  
Significant Risk ◽  
White Spot ◽  
Fluoride Varnish ◽  
Cochrane Library ◽  
White Spot Lesions ◽  
Manual Search ◽  
Orthodontic Patients

Aim: The aim of this study is to critically review the studies that studied the effect of Chlorhexidine varnish and fluoride varnish on White Spot Lesion (WSL) in patients undergoing orthodontic treatment. Materials and Methods: The electronic database PubMed, The Cochrane Library, Medline, Embase, Google Scholar, Web of Knowledge along with a complimentary manual search of all orthodontic journals till the first week of December 2019 was searched. English language study performed on humans, randomized or nonrandomized clinical trials, comparing the effect of fluoride and chlorhexidine varnish on WSL was included in the review. Quality assessment of included studies was performed. Clinical Significance: The need for an adjunct oral hygiene aid to reduce the incidence and prevalence of white spot lesions in orthodontic patients is necessary. The use of these varnishes will aid in the same and thus make the adverse effects of fixed orthodontic treatment negligible. Review of Literature: Enamel demineralization is a significant risk associated with orthodontic treatment when oral hygiene is poor. Prevention of demineralization during orthodontic treatment is one of the greatest challenges faced by clinicians despite modern advances in caries prevention. The development of White Spot Lesions (WSLs) is attributed to prolonged plaque accumulation around the brackets. Results: The search identified a total of 3 studies that were included in this review. One study had Low risk of bias and the remaining 2 studies had moderate overall risk. Results showed that there was a reduction in the incidence of white spot lesions in orthodontic patients after application of chlorhexidine and Fluoride varnish. Conclusion: Low level evidence is available to conclude that the use of chlorhexidine varnishes and fluoride varnishes reduces the prevalence of white spot lesions in patients undergoing fixed orthodontic treatment. Due to its limitations, the results of this systematic review should be handled with caution and further well-planned Randomized Clinical Trial (RCT) are needed to provide a discrete conclusion.

scholarly journals Efficacy of fluoride varnish for prevention of white spot lesions during orthodontic treatment with fixed appliances: A systematic review study

2017 ◽  
Vol 4 (08) ◽  
pp. 1513 ◽  
Author(s):  
Farshad Rahimi ◽  
Masoud Sadeghi ◽  
Hamid Reza Mozaffari
Keyword(s):  
Systematic Review ◽  
Orthodontic Treatment ◽  
White Spot ◽  
Fluoride Varnish ◽  
Cochrane Library ◽  
White Spot Lesions ◽  
Resin Infiltration ◽  
Fixed Appliances ◽  
Review Study ◽  
Orthodontic Devices

Background: White spot lesions (WSLs) are a problem commonly found in patients who use orthodontic devices. Fluoride varnish can reduce WSLs during orthodontic treatment with fixed appliances. The aim of this systematic review was to evaluate the efficacy of fluoride varnish compared with other agents for preventing WSLs during orthodontic treatment. Methods: Studies were searched from four databases- PubMed, Scopus, Web of Science and Cochrane Library- from January 1980 to May 2017; only studies with English abstracts were included. Results: Out of 432 studies searched from the databases, 33 studies were evaluated for eligibility. Of the 33 studies, 19 were excluded with reasons and 14 studies were included in the systematic review. Parameters of WSLs (decalcification score, prevalence, incidence, progression score, ΔQ and ΔZ and DiagnoDent (DD) pen score) were compared for the various treatments. Conclusions: Although there were some limitations for this systematic review study, the review showed that fluoride varnish combined with chlorhexidine (CHX) may be a good treatment for WSLs after orthodontic treatment, especially for a 6-month period, and that resin infiltration might also be effective for preventing WSLs. More studies are needed to further investigate these observations.

scholarly journals Efficacy of fluoride varnish in treating orthodontically-induced white spot lesions: a systematic review and meta-analysis

2021 ◽  
Vol 37 (2) ◽  
pp. 147-156
Author(s):  
Abdulaziz Alrebdi ◽  
Dan Ericson ◽  
Syed Saad B. Qasim ◽  
Ahmad Albahoth ◽  
Abdulelah Al-Sulimani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions

scholarly journals Effectiveness of remineralising agents in prevention and treatment of orthodontically induced white spot lesions: a protocol for a systematic review incorporating network meta-analysis

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Huimin Hu ◽  
Chong Feng ◽  
Zhaowei Jiang ◽  
Lufei Wang ◽  
Sonu Shrestha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Meta Analysis ◽  
White Spot ◽  
Orthodontic Appliances ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
White Spot Lesions ◽  
Prevention And Treatment ◽  
Meta Analyses

Abstract Background White spot lesions (WSLs) are common adverse effects in fixed orthodontic treatment. Remineralising agents are widely used to prevent WSLs formation and are the first-line treatment for existing WSLs. Previous systematic reviews have evaluated the effectiveness of remineralisation agents in the management of WSLs. However, their conclusions were contradictory. The objective of this study will be to compare the effectiveness and safety of current remineralising agents used in the management of WSLs in patients treated with fixed orthodontic appliances in any orthodontic setting. Methods Literature searches will be conducted in several electronic databases (from inception onwards): MEDLINE (via Ovid), Scopus, Embase, the Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL), among others. Grey literature will be identified through searching clinical trials registries. Randomised controlled trials that compared the effectiveness of different remineralisation agents in the prevention and treatment of WSLs will be included. Two researchers will independently screen all citations, full-text articles, and abstract data. The study risk bias will be appraised using an appropriate tool. The primary outcomes will be WSLs incidence and severity of WSLs. Secondary outcomes will be subjective measures of WSLs and adverse effects. The mean difference (MD) and relative risk (RR) with corresponding 95% confidence intervals (CI) will be chosen as effect measures for continuous and binary outcomes, respectively. If feasible, fixed and random-effects pairwise meta-analyses and frequentist network meta-analyses will be conducted where appropriate. Discussion This network meta-analysis will compare the effectiveness of remineralising agents in the prevention and treatment of orthodontically induced WSLs. By integrating the evidence from direct and indirect comparisons and ranking all evaluated interventions, our findings have the potential to help clinicians make more accurate treatment decisions. Systematic review registration PROSPERO CRD42019116852, registered on March 15, 2019

Effect of remineralizing agents on white spot lesions after orthodontic treatment: A systematic review

2013 ◽  
Vol 143 (3) ◽  
pp. 376-382.e3 ◽  
Author(s):  
Hong Chen ◽  
Xingguang Liu ◽  
Juan Dai ◽  
Zhiwei Jiang ◽  
Tao Guo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Orthodontic Treatment ◽  
White Spot ◽  
White Spot Lesions

scholarly journals Corrigendum to: Effectiveness of self-applied topical fluorides against enamel white spot lesions from multi-bracketed fixed orthodontic treatment: a systematic review

2019 ◽  
Vol 41 (6) ◽  
pp. 669-669
Author(s):  
Divesh Sardana ◽  
Sheetal Manchanda ◽  
Manikandan Ekambaram ◽  
Yanqi Yang ◽  
Colman P McGrath ◽  
...  
Keyword(s):  
Systematic Review ◽  
Orthodontic Treatment ◽  
White Spot ◽  
White Spot Lesions ◽  
Topical Fluorides

scholarly journals Interventions for orthodontically induced white spot lesions: a systematic review and meta-analysis

2016 ◽  
pp. cjw065 ◽  
Author(s):  
Damian Höchli ◽  
Monika Hersberger-Zurfluh ◽  
Spyridon N. Papageorgiou ◽  
Theodore Eliades
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
White Spot ◽  
White Spot Lesions

scholarly journals Efficacy of fluoride varnish in treating orthodontically-induced white spot lesions: a systematic review and meta-analysis

2021 ◽  
Vol 37 (2) ◽  
pp. 147-156
Author(s):  
Abdulaziz Alrebdi ◽  
Dan Ericson ◽  
Syed Saad B. Qasim ◽  
Ahmad Albahoth ◽  
Abdulelah Al-Sulimani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions
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