scholarly journals Corrigendum to “Anti-inflammatory and antioxidant activity of the hot water-soluble polysaccharides from Anacyclus pyrethrum (L.) Lag. Roots” [J. Ethnopharmacol. 281 (2021) 114491]

2022 ◽  
Vol 284 ◽  
pp. 114769
Author(s):  
Keltoum Alioueche Karboua ◽  
Lilia Benosmane ◽  
Selma Namoune ◽  
Khaoula Ouled-Diaf ◽  
Nora Ghaliaoui ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Water Soluble ◽  
Hot Water ◽  
Anti Inflammatory

Anti-inflammatory and antioxidant activity of the hot water-soluble polysaccharides from Anacyclus pyrethrum (L.) Lag. roots

2021 ◽  
pp. 114491
Author(s):  
Keltoum Alliouche Kerboua ◽  
Lilia Benosmane ◽  
Selma Namoune ◽  
Khaoula Ouled-Diaf ◽  
Nora Ghaliaoui ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Water Soluble ◽  
Hot Water ◽  
Anti Inflammatory

scholarly journals Beneficial Health Potential of Algerian Polysaccharides Extracted from Plantago ciliata Desf. (Septentrional Sahara) Leaves and Seeds

2021 ◽  
Vol 11 (9) ◽  
pp. 4299
Author(s):  
Noura Addoun ◽  
Zakaria Boual ◽  
Cédric Delattre ◽  
Toufik Chouana ◽  
Christine Gardarin ◽  
...  
Keyword(s):  
Innate Immune System ◽  
Biological Activities ◽  
Structural Features ◽  
Traditional Healers ◽  
Innate Immune ◽  
Water Soluble ◽  
Hot Water ◽  
Indigenous Plants ◽  
Hot Water Extraction ◽  
Anti Inflammatory

Today, an ethnobotanical approach makes sense for identifying new active bioactive chemicals from uses of indigenous plants. Two water-soluble enriched polysaccharide fractions (L-PSPN and S-PSPN) were extracted by hot water extraction from the leaves and seeds of Plantago ciliata Desf. (1798), a Mzab indigenous herb currently used in Algeria by traditional healers. Primary investigation was performed for describing the main structural features of these polysaccharides (pectin- and heteroxylan-like compositions) by using colorimetric assays, FTIR spectroscopy, HPAEC/PAD and GC/MS-EI analyses. Some biological activities were also monitored, such as anticomplement, anti-inflammatory (phagocytic ability, NOX2 and MPO inhibitions) and anti-diabetic (α-amylase and α-glucosidase inhibitions). L-PSPC seems able to moderately modulate innate immune system (IC50 around 100 µg/mL) and contribute to wound-healing processes (IC50 close to 217 vs. 443 µg/mL for sodium heparin). S-PSPC shows some potential as an anti-hyperglycemic (IC50 around 4.7 mg/mL) and anti-inflammatory (IC50 ranging from 111 to 203 µg/mL) agent, as well as other (fiber) psyllium-like polysaccharides extracted from Plantago species.

scholarly journals Assessment of the Quality and Evaluation of the Antioxidant Potential of a Novel Sri Lankan Ayurvedic Polyherbal Formulation

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
H. P. Wakkumbura ◽  
W. M. D. Wickramaarachchi ◽  
L. D. A. M. Arawwawala ◽  
J. A. Liyanage ◽  
R. P. V. J. Rajapakse
Keyword(s):  
Cold Water ◽  
Antioxidant Properties ◽  
Water Soluble ◽  
Hot Water ◽  
Antioxidant Potential ◽  
In Vitro Assays ◽  
Phytochemical Screening ◽  
Anti Inflammatory ◽  
Water Extractable

Background. In Sri Lanka, a Polyherbal Ayurvedic Formulation (PHAF), which consists of powders of seven medicinal plants, is being trialed for use as an anti-inflammatory drug. In general, anti-inflammatory drugs have good antioxidant properties. Therefore, in the present study, an attempt was made to assess the quality and evaluate the antioxidant potential of PHAF. Methods. Physicochemical parameters such as ash content, extractable matter, phytochemical screening for secondary metabolites, levels of heavy metals, and microbes were determined according to standard protocols. Antioxidant activity was evaluated using five in vitro assays: total polyphenolic content (TPC), total flavonoid content (TFC), ORAC (oxygen radical absorbance capacity), DPPH (1,1-diphenyl-2-picryl-hydrazyl), and ABTS (2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt. Results. PHAF contained 5.6 ± 0.2% of moisture, 6.5 ± 0.1% of total ash, 1.4 ± 0.1% of water soluble ash, 0.9 ± 0.0% of acid insoluble ash, 7.7 ± 0.2% of hot water extractable matter, 3.9 ± 0.1% of cold water extractable matter, 10.5 ± 4.1% of hot-ethanol extractable matter, and 8.4 ± 0.2% of cold-ethanol extractable matter. Phytochemical screening revealed the presence of phenolic compounds, tannins, flavonoids, coumarins, and saponins in both aqueous and ethanolic extracts of the drug. TPC, TFC, ORAC, DPPH, and ABTS of aqueous and ethanol extracts of PHAF were 103.65 ± 4.94 and 327.07 ± 9.65 mg gallic acid equivalents/g extract, 76.6 ± 5.83 and 224.6 ± 8.42 mg quercetin equivalents/g of extract, 481.11 ± 17.30 and 1481.44 ± 30.20 mg trolox equivalents/g of extract, 79.50 ± 4.42 and 227.17 ± 6.16 mg trolox equivalents/g of extract, and 198.20 ± 4.55 and 577.08 ± 5.48 mg trolox equivalents/g of extract, respectively. Conclusion. Ethanolic extract of PHAF is better than aqueous extract in terms of antioxidant properties.

scholarly journals Composition of Brazil Nut (Bertholletia excels HBK), Its Beverage and By-Products: A Healthy Food and Potential Source of Ingredients

Foods ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 3007
Author(s):  
Wilson V. Vasquez-Rojas ◽  
Diana Martín ◽  
Beatriz Miralles ◽  
Isidra Recio ◽  
Tiziana Fornari ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Unsaturated Fatty Acids ◽  
Water Soluble ◽  
Hot Water ◽  
Brazil Nut ◽  
Sediment Fraction ◽  
By Products ◽  
Lipid Components

The consumption of plant-based beverages is a growing trend and, consequently, the search for alternative plant sources, the improvement of beverage quality and the use of their by-products, acquire great interest. Thus, the purpose of this work was to characterize the composition (nutrients, phytochemicals and antioxidant activity) of the Brazil nut (BN), its whole beverage (WBM), water-soluble beverage (BM-S), and its by-products of the beverage production: cake, sediment fraction (BM-D), and fat fraction (BM-F). In this study, advanced methodologies for the analysis of the components were employed to assess HPLC-ESI-QTOF (phenolic compounds), GC (fatty acids), and MALDI-TOF/TOF (proteins and peptides). The production of WBM was based on a hot water extraction process, and the production of BM-S includes an additional centrifugation step. The BN showed an interesting nutritional quality and outstanding content of unsaturated fatty acids. The investigation found the following in the composition of the BN: phenolic compounds (mainly flavan-3-ols as Catechin (and glycosides or derivatives), Epicatechin (and glycosides or derivatives), Quercetin and Myricetin-3-O-rhamnoside, hydroxybenzoic acids as Gallic acid (and derivatives), 4-hydroxybenzoic acid, ellagic acid, Vanillic acid, p-Coumaric acid and Ferulic acid, bioactive minor lipid components (β-Sitosterol, γ-Tocopherol, α-Tocopherol and squalene), and a high level of selenium. In beverages, WBM had a higher lipid content than BM-S, a factor that influenced the energy characteristics and the content of bioactive minor lipid components. The level of phenolic compounds and selenium were outstanding in both beverages. Hydrothermal processing can promote some lipolysis, with an increase in free fatty acids and monoglycerides content. In by-products, the BM-F stood out due to its bioactive minor lipid components, the BM-D showed a highlight in protein and mineral contents, and the cake retained important nutrients and phytochemicals from the BN. In general, the BN and its beverages are healthy foods, and its by-products could be used to obtain healthy ingredients with appreciable biological activities (such as antioxidant activity).

scholarly journals Structural Characterization of Water-Soluble Polysaccharides from Sophora flavescensAit. and Their Anti-Inflammatory Evaluation Based on NO Release

2020 ◽  
Author(s):  
Yi-Xuan Li ◽  
Ke-Gang Linghu ◽  
Si-Liang Jiang ◽  
Yong-Sheng Cui ◽  
Cai-Xia Dong ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Water Extract ◽  
Exchange Chromatography ◽  
Water Soluble ◽  
Hot Water ◽  
Raw 264.7 Cells ◽  
Sophora Flavescens ◽  
No Release ◽  
Anti Inflammatory

Abstract Background: The dried roots of Sophora flavescens Ait. are traditionally used as Sophora Flavescens (Kushen in Chinese) to treat inflammatory diseases. It is traditionally served as a decoction, and polysaccharides represent one the major chemical constituents of this decoction. How about the structure of S. flavescens polysaccharides and whether they have anti-inflammatory activity should be uncovered.Methods: The purified polysaccharides were isolated through a combination of ion-exchange chromatography on DEAE 650 M and gel filtration on Superdex G-200 from hot water extract of S. flavescens. Structure was characterized by chemical derivatization as well as HPLC, FT-IR, GC-MS and NMR technologies. The preliminary in vitro antiinflammation activity was tested on RAW 264.7 cells upon NO release inhibition.Results: In this study, four polysaccharides, namely, SFNP-1, SFNP-2, SFAP-1, and SFAP-2, were isolated from S. flavescens. Results showed that both SFNP-1 and SFNP-2 contained (1→4)-linked glucans with small amounts of side chains at the O-4 position of the backbone chain residues. The two acidic polysaccharides (i.e.,SFAP-1 and SFAP-2) were identified to be pectin-type polysaccharides mainly containing a homo-galacturanan backbone consisting of α-(1→4)-linked GalAp and methyl-esterified α-(1→4)-linked GalAp residues at a ratio ofapproximately1:1. The bioactivity test revealed that the four purified polysaccharides have no cytotoxicity on RAW264.7andthat SFNP-1 and SFNP-2 show significant stimulating activity. Although the decoction of S. flavescens has been traditionally used as an anti-inflammatory agent, NO release inhibition results showed thatSFAP-1 and SFAP-2, as the major polysaccharides of SFCP, do not have significant anti-inflammatory effects. Conclusions: This result suggests that the anti-inflammatory effect of the decoction of S. flavescens may depend on the presence of alkaloids and not the polysaccharides it contains.

Structural Determination and Antioxidant Activity of a Polysaccharide from the Fruiting Bodies of Cultured Cordyceps sinensis

2009 ◽  
Vol 37 (05) ◽  
pp. 977-989 ◽  
Author(s):  
Ying Wang ◽  
Min Wang ◽  
Yun Ling ◽  
Weiqiang Fan ◽  
Yufeng Wang ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Hydroxyl Radicals ◽  
Average Molecular Weight ◽  
Periodate Oxidation ◽  
Reducing Power ◽  
Water Soluble ◽  
Hot Water ◽  
Partial Acid Hydrolysis ◽  
Scavenging Effect ◽  
Chelating Activity

A water-soluble polysaccharide named CPS1 had been isolated from C. sinensis mycelium by hot water extraction, ethanol precipitation, anion-exchange, and gel-permeation chromatography. UV spectra, FTIR spectra, partial acid hydrolysis, PMP precolumn derivation, periodate oxidation and Smith degradation studies were conducted to elucidate its structure. The results indicated that CPS1 was a glucomannogalactan with the monosaccharide composition of glucose: mannose: galactose = 2.8: 2.9: 1. The total carbohydrate content of CPS1 was 99.0%. The weight-average molecular weight was 8.1 × 103 Da . The results predicted (1 → 2) and (1 → 4)-linkage of mannose, (1 → 3)-linkage of galactose, (1 → ) and (1 → 3, 6)-linkage of glucose composed the backbone of CPS1. CPS1 was also evaluated for its antioxidant activity in vitro, including scavenging effects on the hydroxyl radicals, the reducing power, Fe2+ -chelating activity, scavenging effect on superoxide radicals, as well as the inhibition of hydrogen peroxide induced haemolysis. CPS1 showed a high antioxidant effect, especially scavenging effect of hydroxyl radicals, the reducing power and Fe2+ -chelating activity. The results provide scientific support for the antioxidant activity and indicated a connection between antioxidant activity and reparation of renal failure.

CARBOHYDRATE PRODUCT FOR THERAPEUTIC AND PROPHYLACTIC PURPOSES

2020 ◽  
pp. 89-94
Author(s):  
Khvorova L.S. ◽  
Byzov V.A.
Keyword(s):  
Antioxidant Activity ◽  
Uric Acid ◽  
Phenolic Compounds ◽  
Mental Stress ◽  
The Body ◽  
Hot Water ◽  
Preventive Effect ◽  
Activity Inhibition ◽  
Medicinal Properties ◽  
Simple Carbohydrates

The article is devoted to the creation of a carbohydrate product with rosehip extract in the form of sweets (glucose Fudge) with a therapeutic and preventive effect aimed at restoring the body of people exposed to intense physical and mental stress and the effects of damaging environmental factors. As carbohydrates in the recipe, simple carbohydrates (glucose) and complex carbohydrates in the form of starch molasses containing (maltose, tri - Tetra - sugars, dextrins) are used. Glucose in the formulation is the main energy ingredient, sweetener and structure-forming component that gives the product a solid consistency due to crystallization. The medicinal effect of the product is provided by rosehip extract. Numerous published studies have established its vitamin, immunostimulating and antioxidant activity, inhibition of uric acid formation and obesity, which are associated with flavonoids, other phenolic compounds, and vitamins. The list of medicinal properties of rosehip extract shows the feasibility of using it in additional nutrition of people in order to prevent diseases. For the formulation of our sweets, the extraction of crushed rosehip fruits was carried out three times with hot water at a temperature of 65-700C, followed by concentration of the extract under vacuum to 25-30% SV. The resulting extract-concentrate was introduced into the formulation in a dosage of 5.5% SV per 100 g of SV glucose Fudge, which provided the necessary dosage for the product when used from 3 (for children) to 10 sweets a day (for adults) for the prevention of colds.

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