Exposure to ambient fine particulate matter impedes the function of spleen in the mouse metabolism of high-fat diet

2022 ◽  
Vol 423 ◽  
pp. 127129
Author(s):  
Zhao He ◽  
Hongna Zhang ◽  
Yuanyuan Song ◽  
Zhu Yang ◽  
Zongwei Cai
2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Iberê Machado Kostrycki ◽  
Guilherme Wildner ◽  
Yohanna Hannah Donato ◽  
Analú Bender dos Santos ◽  
Lílian Corrêa Costa Beber ◽  
...  

Obesity, air pollution, and exercise induce alterations in the heat shock response (HSR), in both intracellular 70 kDa heat shock proteins (iHSP70) and the plasmatic extracellular form (eHSP72). Extra-to-intracellular HSP70 ratio (H-index = eHSP70/iHSP70 ratio) represents a candidate biomarker of subclinical health status. This study investigated the effects of moderate- and high-intensity exercise in the HSR and oxidative stress parameters, in obese mice exposed to fine particulate matter (PM2.5). Thirty-day-old male isogenic B6129F2/J mice were maintained for 16 weeks on standard chow or high-fat diet (HFD). Then, mice were exposed to either saline or 50 μg of PM2.5 by intranasal instillation and subsequently maintained at rest or subjected to moderate- or high-intensity swimming exercise. HFD mice exhibited high adiposity and glucose intolerance at week 16th. HFD mice submitted to moderate- or high-intensity exercise were not able to complete the exercise session and showed lower levels of eHSP70 and H-index, when compared to controls. PM2.5 exposure modified the glycaemic response to exercise and modified hematological responses in HFD mice. Our study suggests that obesity is a critical health condition for exercise prescription under PM2.5 exposure.


2020 ◽  
Vol 391 ◽  
pp. 122203 ◽  
Author(s):  
Jinjin Jiang ◽  
Yang Li ◽  
Shuang Liang ◽  
Baiyang Sun ◽  
Yanfeng Shi ◽  
...  

2021 ◽  
Vol 145 ◽  
pp. 111215
Author(s):  
Lílian Corrêa Costa-Beber ◽  
Pauline Brendler Goettems-Fiorin ◽  
Jaíne Borges dos Santos ◽  
Paula Taís Friske ◽  
Matias Nunes Frizzo ◽  
...  

2016 ◽  
Vol 72 (4) ◽  
pp. 643-656 ◽  
Author(s):  
Pauline Brendler Goettems-Fiorin ◽  
Bethânia Salamoni Grochanke ◽  
Fernanda Giesel Baldissera ◽  
Analu Bender dos Santos ◽  
Paulo Ivo Homem de Bittencourt ◽  
...  

2020 ◽  
Author(s):  
Yazhen Gong ◽  
Shanjun Li ◽  
Nicholas Sanders ◽  
Guang Shi

2021 ◽  
pp. 106386
Author(s):  
Heyu Yin ◽  
Sina Parsnejad ◽  
Ehsan Ashoori ◽  
Hao Wan ◽  
Wen Li ◽  
...  

2001 ◽  
Vol 32 ◽  
pp. 353-354
Author(s):  
E. BRÜGGEMANN ◽  
T. GNAUK ◽  
K. MULLER ◽  
H. HERRMANN

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