scholarly journals 196 Rare presentation of Vesiculobullous Lyme Disease: A case series

2021 ◽  
Vol 141 (5) ◽  
pp. S35
Author(s):  
H. Doughty ◽  
K. O'Hern ◽  
D. Barton ◽  
J. Carter
2016 ◽  
Vol 55 (6) ◽  
pp. 1241-1244 ◽  
Author(s):  
Jason R. Miller ◽  
Karl W. Dunn ◽  
Domenick Braccia ◽  
Louis J. Ciliberti ◽  
Dina K. Becker ◽  
...  

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
John Aucott ◽  
Candis Morrison ◽  
Beatriz Munoz ◽  
Peter C Rowe ◽  
Alison Schwarzwalder ◽  
...  
Keyword(s):  

2015 ◽  
Vol 204 (4) ◽  
pp. W398-W404 ◽  
Author(s):  
Anil Chauhan ◽  
Naveen Garg ◽  
Christine O. Menias ◽  
Catherine E. Devine ◽  
Priya R. Bhosale ◽  
...  

2019 ◽  
Vol 58 (6) ◽  
pp. e377-e378
Author(s):  
Osman M.A. Mahmoud ◽  
Ashraf Taha ◽  
Ashraf Hosny ◽  
Hesham Aboloyoun ◽  
Ayman Hasaballah

2012 ◽  
Vol 05 (06) ◽  
Author(s):  
Navin Ram ◽  
Bharat Behera ◽  
Sudheer Rathi ◽  
Sameer Trivedi ◽  
Uday Shankar Dwivedi

2021 ◽  
Vol 36 (6) ◽  
pp. 1123-1124
Author(s):  
Alexandra Rudd-Barnard ◽  
Sarah Jarvandi ◽  
Roxanne Rapoport ◽  
Sue Smith ◽  
Natalia Witkowska

Abstract Objectives The purpose of this study was to investigate the characteristics of physician diagnosed Neurological Lyme disease (NLD) using Quantitative EEG and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). We hypothesize that findings would include more slow wave (Delta/Theta) activity that is consistent with the severity reported dysfunction. Methods Subjects consisted of four adult females with a physician provided diagnosis of NLD. EEG was recorded from 21 sites during an eyes open and eyes-closed resting conditions. Raw EEG data was made quantifiable (qEEG) through Fourier transformation to determine z-score derived cortical and subcortical slow wave activity. The RBANS was used to assess each subject’s functioning. Results (See Imaging). Subject 1. Theta: 3.7. Alpha: 2.3. Theta: 3.2. Alpha: 2.5. RBANS - 96. Subject 2. Theta: 1.9. Alpha: 3.1. Theta: 2.3. Alpha: 4.4. RBANS - 76. Subject 3. Theta: 3.4. Alpha: 2.8. Theta: 3.5. Alpha: 2.1. RBANS - 110. Subject 4. Theta: 3.6. Alpha: 3.0. Theta: 3.3. Alpha: 2.8. RBANS - 100. Conclusions NLD subjects within this study all demonstrated elevated subcortical frontal and frontotemporal theta and alpha. Elevation in cortical slow wave activity was found for subjects with greater reported symptomatology and may suggest either less severe course of disease or serve as a recovery marker. RBANS assessment variables were not completely sensitive in detection of subject reported challenges. Implications for conceptualization, treatment, and disease monitoring are highlighted. Directions for future research will also be discussed.


2021 ◽  
pp. 000486742110437
Author(s):  
Jesse Schnall ◽  
Georgina Oliver ◽  
Sabine Braat ◽  
Richard Macdonell ◽  
Katherine B Gibney ◽  
...  

Objectives(s): To characterise the clinical profile, aetiology and treatment responsiveness of ‘Australian Lyme’, or Debilitating Symptom Complexes Attributed to Ticks. Methods: Single-centre retrospective case analysis of patients referred to the Infectious Diseases Unit at Austin Health – a tertiary health service in Heidelberg, Australia – between 2014 and 2020 for investigation and treatment of suspected Debilitating Symptom Complexes Attributed to Ticks. Patients were included if they had debilitating symptoms suggested by either themselves or the referring clinician as being attributed to ticks. Results: Twenty-nine Debilitating Symptom Complexes Attributed to Ticks cases were included in the analysis. Other than Lyme disease (83%), the most common prior medical diagnoses were Epstein–Barr virus (38%), chronic fatigue syndrome (28%) and fibromyalgia (24%). Prior histories of anxiety (48%) and depression (41%) were common. The most frequently reported symptoms included fatigue (83%), headache (72%) and arthralgia (69%). National Association of Testing Authorities/Royal College of Pathologists of Australasia–accredited serology was not diagnostic of acute infective causes, including Lyme disease, in any patient. Of 25 cases with available data, 23 (92%) had previously been prescribed antimicrobials, with 53% reporting benefit from them. The most common diagnoses made by our hospital were chronic fatigue syndrome (31%), migraines (28%) and fibromyalgia (21%). Only one patient’s symptoms were not accounted for by other diagnoses. Conclusion: This is the first case series of patients with Debilitating Symptom Complexes Attributed to Ticks. They had high rates of other medically unexplained syndromes, and no evidence of acute Lyme disease, or any common organic disease process. Debilitating Symptom Complexes Attributed to Ticks remains medically unexplained, and may therefore be due to an as yet unidentified cause, or may be considered a medically unexplained syndrome similar to conditions such as chronic fatigue syndrome.


Author(s):  
Marte van Keulen ◽  
Jonathan Pace ◽  
Christopher J. Burant ◽  
David L. Penn ◽  
Betsy Wilson ◽  
...  

Abstract Introduction The incidence of vestibular schwannoma is reported as 12 to 54 new cases per million per year, increasing over time. These patients usually present with unilateral sensorineural hearing loss, tinnitus, or vertigo. Rarely, these patients present with symptoms of hydrocephalus or vision changes. Objective The study aimed to evaluate the surgical management of vestibular schwannoma at a single institution and to identify factors that may contribute to hydrocephalus, papilledema, and the need for pre-resection diversion of cerebrospinal fluid. Patients and Methods A retrospective review examining the data of 203 patients with vestibular schwannoma managed with surgical resection from May 2008 to May 2020. We stratified patients into five different groups to analyze: tumors with a diameter of ≥40 mm, clinical evidence of hydrocephalus, and of papilledema, and patients who underwent pre-resection cerebrospinal fluid (CSF) diversion. Results From May 2008 to May 2020, 203 patients were treated with surgical resection. Patients with tumors ≥40 mm were more likely to present with visual symptoms (p < 0.001). Presentation with hydrocephalus was associated with larger tumor size (p < 0.001) as well as concomitant visual symptoms and papilledema (p < 0.001). Patients with visual symptoms presented at a younger age (p = 0.002) and with larger tumors (p < 0.001). Conclusion This case series highlights the rare presentation of vision changes and hydrocephalus in patients with vestibular schwannoma. We recommend urgent CSF diversion for patients with visual symptoms and hydrocephalus, followed by definitive resection. Further, vision may still deteriorate even after CSF diversion and tumor resection.


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