Comment on: Vulvar and vaginal melanomas: A retrospective study spanning 19 years from a tertiary center

Author(s):  
Tomoyuki Kawada
Author(s):  
Swati Rathore ◽  
Ravi Shankar ◽  
Annie P. Vijjeswarapu ◽  
Anuja Abraham ◽  
Bijesh Yadav

Background: Pregnancy is a hypercoaguable state with physiological haemodynamic changes occurring during pregnancy. There is a progressive increase in intravascular volume in second trimester of pregnancy and increase in cardiac output. Pregnancy makes a significant impact on cardiovascular system. It is important to evaluate and study the effect of pregnancy on women with surgically corrected heart conditions so as to preempt potential complications.Methods: This is a retrospective study of patients with prior history of cardiac surgery and their pregnancy outcomes in a tertiary center of Southern India over a period of five years from January 2011 to December 2016.Results: In this study, descriptive statistical analysis was done in 87 women with pregnancy following cardiac surgery. 58.6% were nulliparous. Around 52% had associated obstetric risk factors. The most common cardiac surgery in this population was Mitral valve replacement (40.2%) and Atrial septal defect closure (37.9%). Women belonged to NYHA class I in 90.8% of cases. 58.6% had vaginal delivery and 36.8% had caesarean section. 6 women had postpartum haemorrhage which was medically managed, and 6 women needed ICU care.74.7% women had term deliveries. 18.4 % of the babies were less than 2.5 kg weight at birth. 13 babies required Neonatal ICU care.Conclusions: Maternal and neonatal outcome mainly depends on the functional cardiac status of women before conception. In this study we emphasize on the importance of multidisciplinary team approach involving cardiologist, obstetrician and neonatologist in the management of women with prior cardiac surgery.


2019 ◽  
Vol 65 (07/2019) ◽  
Author(s):  
Melinda Baizat ◽  
Gabriela Zaharie ◽  
Mihaela Iancu ◽  
Daniel Muresan ◽  
Monica Hășmășanu ◽  
...  

2017 ◽  
Vol 58 (9) ◽  
pp. 2110-2117 ◽  
Author(s):  
Xinyu Nan ◽  
Qian Qin ◽  
Cesar Gentille ◽  
Joe Ensor ◽  
Christopher Leveque ◽  
...  

Cureus ◽  
2021 ◽  
Author(s):  
Fatma Alzahrani ◽  
Anas M Fallatah ◽  
Fatimah M Al-Haddad ◽  
Shahad T Khayyat ◽  
Wasayf M AlMehmadi ◽  
...  

2019 ◽  
Vol 6 (7) ◽  
pp. 2458 ◽  
Author(s):  
Deepak Hongaiah ◽  
Abhilash . ◽  
Dharmendra Kumar ◽  
Vijay Kumar S.

Background: Early morning mixer grinder fingertip injuries is encountered predominantly in females. Most of these injuries happened due to improper use of the grinder like keeping hands into the mixer when still the blades on run immediately after switching off the machine and sometimes during washing the jar. It can lead to injury of either single or multiple finger and either at single or multiple levels. Early wound debridement and reconstruction is essential for good functional outcome, prevention of the deformity and to achieve good cosmesis. The objective of the study was to classify the mixer grinder fingertip injuries and to asses treatment outcome of different type of mixer grinder fingertip injuries.Methods: This is a retrospective study involving 12 patients over a period of 2 years. Data was collected from the previous records and was analysed using SPSS 22 version software. Categorical data was represented in the form of Frequencies and proportions.Results: In the present study most common age group involved is between 26 and 30 years (66.7%) with female predominance and most common hand involved was right hand. D3 involved most frequently and at multiple levels. Most of them were treated under wrist block followed by digital block with very good short term and long term outcome.Conclusions: The treatment of the fingertip injuries should be aimed at preserving the length of the digit by giving adequate wound debridement and primary suturing/flap reconstruction when possible to provide soft-tissue coverage with protective sensation at a minimum.


2020 ◽  
Author(s):  
Yong-xue Wang ◽  
Shan Deng

Abstract Background: Adnexal torsion during pregnancy is a gynecological emergency. Delayed diagnosis and treatment can cause ovarian necrosis and fetal loss. This study assessed the clinical characteristics, treatment and outcomes of adnexal torsion in pregnant women.Methods: A retrospective study was conducted at a tertiary center between January 2008 and January 2018. Eighty-two pregnant women with surgically confirmed adnexal torsion were included. The clinical characteristics, ultrasound data, surgical interventions and pregnancy outcomes were analyzed.Results: The median age of the patients was 28 (range, 18-38) years. The median gestational age was 11 (range, 6-31) weeks: 53 (64.6%) were in the first trimester, 21 (25.6%) were in the second trimester, and 8 (9.8%) were in the third trimester. The most common symptoms and signs were sudden pelvic pain (100%) and adnexal or pelvic masses (97.6%), followed by nausea and vomiting (61%). The Doppler blood flow signal disappeared in 62.5% of the patients. Sixty-three (76.8%) patients underwent laparoscopy, and 29 (24.2%) underwent laparotomy. The median gestational age in patients undergoing laparotomy was higher than that in those undergoing laparoscopy (26 weeks vs 10 weeks, p<0.001). Fifty-three (64.6%) patients underwent conservative surgery, with 48 detorsions and cystectomies, 2 detorsions and cyst fenestrations, 1 detorsion only and 2 salpingectomies only. Twenty-nine (25.4%) patients underwent unilateral salpingo-oophorectomy. There were no cases of postoperative thrombosis, spontaneous abortion or recurrence during the same pregnancy. Seven patients underwent simultaneous artificial abortion. One patient experienced intrauterine fetal death, and 74 patients had live births.Conclusion: Surgical intervention was required as soon as possible. Laparoscopic conservative surgery is safe and may be appropriate to preserve ovarian function.


2021 ◽  
Author(s):  
Martina Peinkhofer ◽  
Benedetta Bossini ◽  
Arturo Penco ◽  
Manuela Giangreco ◽  
Maria Chiara Pellegrin ◽  
...  

Abstract Objective: The study aimed to evaluate differences in pediatric endocrine stimulation tests after the advent of COVID-19 pandemics.Methods: Retrospective study with data collection for pediatric endocrine stimulation tests performed in 2019 e 2020 in a tertiary center.Results: Overall, 251 tests were performed on 190 patients in 2020, compared to 278 tests on 206 patients in 2019 (-10% tests; -8% children evaluated). A significant reduction was found in tests to diagnose growth hormone deficiency (GHD) (-35%), while LHRH tests increased (+22%). A reduction of 30% in GHD diagnosis was observed. Diagnosis of central precocious puberty (CPP) increased by 38% compared to 2019, mainly in females. Conclusion: This study found a significant reduction of tests investigating GHD during COVID-19 pandemics. It also showed a clinically meaningful increase in cases of CPP in girls. These results suggest the need for families and pediatricians to monitor children's growth during isolation and enlighten new perspectives towards conditions associated with lockdown restrictions as increased screen time, social isolation, and children's anxiety as possible triggers of CPP.


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