Study on enhanced extraction and seasonal variation of secondary metabolites in Eucommia ulmoides leaves using deep eutectic solvents

2022 ◽  
Vol 209 ◽  
pp. 114514
Author(s):  
Shengbo Luo ◽  
Xiaomei Ren ◽  
Xiqing Shi ◽  
Kan Zhong ◽  
Zijia Zhang ◽  
...  
2019 ◽  
Vol 9 (19) ◽  
pp. 4169 ◽  
Author(s):  
Dimitris Skarpalezos ◽  
Anastasia Detsi

The present review article attempts to summarize the use of deep eutectic solvents in the extraction of flavonoids, one of the most important classes of plant secondary metabolites. All of the applications reviewed have reported success in isolation and extraction of the target compounds; competitive, if not superior, extraction rates compared with conventional solvents; and satisfactory behavior of the extract in the latter applications (such as direct analysis, synthesis, or catalysis), wherever attempted.


PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0187235 ◽  
Author(s):  
Ernesto Ramírez-Briones ◽  
Ramón Rodríguez-Macías ◽  
Eduardo Salcedo-Pérez ◽  
Norma Martínez-Gallardo ◽  
Axel Tiessen ◽  
...  

Química Nova ◽  
2012 ◽  
Vol 35 (11) ◽  
pp. 2139-2145 ◽  
Author(s):  
Dayana Rubio Gouvea ◽  
Leonardo Gobbo-Neto ◽  
Humberto T. Sakamoto ◽  
Norberto Peporine Lopes ◽  
João Luís Callegari Lopes ◽  
...  

2019 ◽  
Vol 41 (1) ◽  
pp. 169-169
Author(s):  
Wen Yan Liu Wen Yan Liu ◽  
Zi Ling Zi Ling ◽  
Dong Dong ◽  
Ke Huan Li Ke Huan Li ◽  
Jian Hua Shao Jian Hua Shao ◽  
...  

Eucommia ulmoides Oliv., exhibiting diverse bioactivities including antimicrobial, antioxidant, neuroprotective, anti-tumor and anti-inflammatory properties, has long been known as an active ingredient commonly used in antihypertensive herbal prescriptions in China. The 95% ethanol extract of the barks of E. ulmoides showed antimicrobial and antioxidant activities and then was isolated by bioactivity-guided fractionation to obtain a new cinnamyl glucoside, 1-O-trans-cinnamoyl-β-D-apiofuranosyl-(1→6)-β-D-glucopyranose (1), together with twenty known secondary metabolites (2–21). And their structures were identified by extensive spectroscopic analyses, including 1D and 2D NMR, UV, IR and HRESIMS, and chemical methods. All secondary metabolites were evaluated for their antimicrobial and antioxidant activities in vitro. Compounds 7, 8, 11, and 21 exhibited moderately antimicrobial activity. In the antioxidant activity assay, compounds 3, 7, 11, and 14 showed intense activity in ferric reducing antioxidant power (FRAP) with the values of 9.82 mmol/g, 19.25 mmol/g, 14.52 mmol/g, and 12.58 mmol/g in comparison to Trolox (9.02 mmol/g). And compounds 2, 11, and 14–16 showed more potent activity with IC50 values ranging from 18.34 to 24.36 M than Trolox (26.35 M) in ABTS+• scavenging assay.


2017 ◽  
Vol 16 (5) ◽  
pp. 935-951 ◽  
Author(s):  
Sanae Mouden ◽  
Peter G. L. Klinkhamer ◽  
Young Hae Choi ◽  
Kirsten A. Leiss

2016 ◽  
Vol 66 (1) ◽  
pp. 1-16
Author(s):  
Fatma Ahmed ◽  
Mahmoud Elhaak ◽  
Khalil Saad-Allah ◽  
Mohamed Kashlana

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