Pharmacokinetics, Safety, and Tolerability of Single Oral Doses of a Novel Oxytocin Receptor Antagonist—Cligosiban—in Development for Premature Ejaculation: Three Randomized Clinical Trials in Healthy Subjects

2018 ◽  
Vol 15 (11) ◽  
pp. 1547-1557 ◽  
Author(s):  
Ian H. Osterloh ◽  
Gary J. Muirhead ◽  
Stefan Sultana ◽  
Steven Whaley ◽  
Frans van den Berg ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Receptor Antagonist ◽  
Healthy Subjects ◽  
Premature Ejaculation ◽  
Randomized Clinical Trials ◽  
Oxytocin Receptor ◽  
Oral Doses

Effects of cereal fibers on short-chain fatty acids in healthy subjects and patients: a meta-analysis of randomized clinical trials

2021 ◽  
Author(s):  
Junying Bai ◽  
Yan Li ◽  
Wenhui Zhang ◽  
Mingcong Fan ◽  
Haifeng Qian ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Clinical Trials ◽  
Clinical Studies ◽  
Healthy Subjects ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Cereal Fiber ◽  
Obese Subjects

Cereal fiber supplementation significantly affected fecal SCFA concentrations in randomized clinical studies. A more significant impact appeared in overweight and obese subjects with BMI >29 kg m−2 than in individuals with BMI ≤29 kg m−2.

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