Translational Science Kidney traits on repeat – the role of MUC1 VNTR

2022 ◽  
Author(s):  
Eric Olinger ◽  
Ian Wilson ◽  
Olivier Devuyst ◽  
John A. Sayer
Keyword(s):  
Translational Science

scholarly journals Inflammation and Atherosclerosis

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1197
Author(s):  
Klaus Ley
Keyword(s):  
Clinical Trials ◽  
Animal Models ◽  
Basic Science ◽  
Translational Science ◽  
Special Issue

This 11-chapter Special Issue of Cells spans the gamut from basic science in mechanistic animal models to translational science to outcomes of clinical trials, all focused on the role of inflammation in atherosclerosis [...]

scholarly journals Exploring the potential role of community engagement in evaluating clinical and translational science grant proposals

2018 ◽  
Vol 2 (3) ◽  
pp. 139-146 ◽  
Author(s):  
Jeffrey W. Treem ◽  
Margaret Schneider ◽  
Robynn L. Zender ◽  
Dara H. Sorkin
Keyword(s):  
Community Engagement ◽  
Potential Role ◽  
Review Process ◽  
Translational Science ◽  
Community Members ◽  
Grant Proposals ◽  
Stage Process ◽  
Stage 1 ◽  
The University

IntroductionThis study explored the effects of integrating community members into the evaluation of clinical and translational science grants.MethodsThe University of California, Irvine Institute for Clinical and Translational Sciences (ICTS) engaged 21 community reviewers alongside scientific reviewers in a 2-stage process of evaluating research proposals. In Stage 1 reviewers scored proposals, and during Stage 2 two study sections convened: one a mix of community reviewers and scientific reviewers, and one only engaging scientific reviewers. In total, 4 studies were discussed by both study sections.ResultsComparisons of reviews revealed little difference between ratings of community reviewers and those of scientific reviewers, and that community reviewers largely refrained from critiquing scientific or technical aspects of proposals.ConclusionsThe findings suggest that involving community reviewers early in the grant cycle, and exposing them to the entirety of the review process, can bolster community engagement without compromising the rigor of grant evaluations.

scholarly journals Opportunities for strengthening CTSA evaluation

2019 ◽  
Vol 3 (2-3) ◽  
pp. 59-64 ◽  
Author(s):  
Tanha Patel ◽  
Julie Rainwater ◽  
William M. Trochim ◽  
Julie T. Elworth ◽  
Linda Scholl ◽  
...  
Keyword(s):  
National Level ◽  
Translational Science ◽  
Multiple Stakeholders ◽  
Significant Interest ◽  
Program Funding ◽  
The Common ◽  
Collaborative Evaluation ◽  
Funding Opportunity ◽  
Existing Data

AbstractThe purpose of the article is to describe the progress of the Clinical and Translational Science Award (CTSA) Program to address the evaluation-related recommendations made by the 2013 Institute of Medicine’s review of the CTSA Program and guidelines published in CTS Journal the same year (Trochim et al., Clinical and Translational Science 2013; 6(4): 303–309). We utilize data from a 2018 national survey of evaluators administered to all 64 CTSA hubs and a content analysis of the role of evaluation in the CTSA Program Funding Opportunity Announcements to document progress. We present four new opportunities for further strengthening CTSA evaluation efforts: (1) continue to build the collaborative evaluation infrastructure at local and national levels; (2) make better use of existing data; (3) strengthen and augment the common metrics initiative; and (4) pursue internal and external opportunities to evaluate the CTSA program at the national level. This article will be of significant interest to the funders of the CTSA Program and the multiple stakeholders in the larger consortium and will promote dialog from the broad range of CTSA stakeholders about further strengthening the CTSA Program’s evaluation.

scholarly journals Translational nutrition research at UC Davis-the key role of the Clinical and Translational Science Center

2010 ◽  
Vol 1190 (1) ◽  
pp. 179-183 ◽  
Author(s):  
Sidika Kasim-Karakas ◽  
Dianne Hyson ◽  
Charles Halsted ◽  
Marta Van Loan ◽  
Erica Chedin ◽  
...  
Keyword(s):  
Translational Science ◽  
Science Center ◽  
Nutrition Research

The Role of the Epidemiologist in Clinical and Translational Science

2006 ◽  
Vol 16 (5) ◽  
pp. 409-410 ◽  
Author(s):  
AMERICANCOLLEGEOFEPIDEMIOLOGY
Keyword(s):  
Translational Science

scholarly journals Dissemination and implementation science activities across the Clinical Translational Science Award (CTSA) Consortium: Report from a survey of CTSA leaders

2019 ◽  
Vol 4 (3) ◽  
pp. 188-194 ◽  
Author(s):  
Rowena J. Dolor ◽  
Enola Proctor ◽  
Kathleen R. Stevens ◽  
Leslie R. Boone ◽  
Paul Meissner ◽  
...  
Keyword(s):  
Knowledge Translation ◽  
Implementation Science ◽  
Working Group ◽  
Dissemination And Implementation ◽  
Translational Science ◽  
Formal Element ◽  
Dissemination And Implementation Science ◽  
Qualitative Analyses ◽  
Science Activities

AbstractIntroduction:Dissemination and implementation (D&I) science is not a formal element of the Clinical Translational Science Award (CTSA) Program, and D&I science activities across the CTSA Consortium are largely unknown.Methods:The CTSA Dissemination, Implementation, and Knowledge Translation Working Group surveyed CTSA leaders to explore D&I science-related activities, barriers, and needed supports, then conducted univariate and qualitative analyses of the data.Results:Out of 67 CTSA leaders, 55.2% responded. CTSAs reported directly funding D&I programs (54.1%), training (51.4%), and projects (59.5%). Indirect support (e.g., promoted by CTSA without direct funding) for D&I activities was higher – programs (70.3%), training (64.9%), and projects (54.1%). Top barriers included funding (39.4%), limited D&I science faculty (30.3%), and lack of D&I science understanding (27.3%). Respondents (63.4%) noted the importance of D&I training and recommended coordination of D&I activities across CTSAs hubs (33.3%).Conclusion:These findings should guide CTSA leadership in efforts to raise awareness and advance the role of D&I science in improving population health.

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