Machine learning for mathematical models of HCV kinetics during antiviral therapy

2021 ◽  
pp. 108756
Author(s):  
Alexander Churkin ◽  
Stephanie Kriss ◽  
Asher Uziel ◽  
Ashish Goyal ◽  
Rami Zakh ◽  
...  
2020 ◽  
Vol 89 ◽  
pp. 20-29
Author(s):  
Sh. K. Kadiev ◽  
◽  
R. Sh. Khabibulin ◽  
P. P. Godlevskiy ◽  
V. L. Semikov ◽  
...  

Introduction. An overview of research in the field of classification as a method of machine learning is given. Articles containing mathematical models and algorithms for classification were selected. The use of classification in intelligent management decision support systems in various subject areas is also relevant. Goal and objectives. The purpose of the study is to analyze papers on the classification as a machine learning method. To achieve the objective, it is necessary to solve the following tasks: 1) to identify the most used classification methods in machine learning; 2) to highlight the advantages and disadvantages of each of the selected methods; 3) to analyze the possibility of using classification methods in intelligent systems to support management decisions to solve issues of forecasting, prevention and elimination of emergencies. Methods. To obtain the results, general scientific and special methods of scientific knowledge were used - analysis, synthesis, generalization, as well as the classification method. Results and discussion thereof. According to the results of the analysis, studies with a mathematical formulation and the availability of software developments were identified. The issues of classification in the implementation of machine learning in the development of intelligent decision support systems are considered. Conclusion. The analysis revealed that enough algorithms were used to perform the classification while sorting the acquired knowledge within the subject area. The implementation of an accurate classification is one of the fundamental problems in the development of management decision support systems, including for fire and emergency prevention and response. Timely and effective decision by officials of operational shifts for the disaster management is also relevant. Key words: decision support, analysis, classification, machine learning, algorithm, mathematical models.


Author(s):  
Soundariya R.S. ◽  
◽  
Tharsanee R.M. ◽  
Vishnupriya B ◽  
Ashwathi R ◽  
...  

Corona virus disease (Covid - 19) has started to promptly spread worldwide from April 2020 till date, leading to massive death and loss of lives of people across various countries. In accordance to the advices of WHO, presently the diagnosis is implemented by Reverse Transcription Polymerase Chain Reaction (RT- PCR) testing, that incurs four to eight hours’ time to process test samples and adds 48 hours to categorize whether the samples are positive or negative. It is obvious that laboratory tests are time consuming and hence a speedy and prompt diagnosis of the disease is extremely needed. This can be attained through several Artificial Intelligence methodologies for prior diagnosis and tracing of corona diagnosis. Those methodologies are summarized into three categories: (i) Predicting the pandemic spread using mathematical models (ii) Empirical analysis using machine learning models to forecast the global corona transition by considering susceptible, infected and recovered rate. (iii) Utilizing deep learning architectures for corona diagnosis using the input data in the form of X-ray images and CT scan images. When X-ray and CT scan images are taken into account, supplementary data like medical signs, patient history and laboratory test results can also be considered while training the learning model and to advance the testing efficacy. Thus the proposed investigation summaries the several mathematical models, machine learning algorithms and deep learning frameworks that can be executed on the datasets to forecast the traces of COVID-19 and detect the risk factors of coronavirus.


Author(s):  
Óscar Fontenla-Romero ◽  
Bertha Guijarro-Berdiñas ◽  
David Martinez-Rego ◽  
Beatriz Pérez-Sánchez ◽  
Diego Peteiro-Barral

Machine Learning (ML) addresses the problem of adjusting those mathematical models which can accurately predict a characteristic of interest from a given phenomenon. They achieve this by extracting information from regularities contained in a data set. From its beginnings two visions have always coexisted in ML: batch and online learning. The former assumes full access to all data samples in order to adjust the model whilst the latter overcomes this limiting assumption thus expanding the applicability of ML. In this chapter, we review the general framework and methods of online learning since its inception are reviewed and its applicability in current application areas is explored.


SIAM Review ◽  
1993 ◽  
Vol 35 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Sunetra Gupta ◽  
Roy M. Anderson ◽  
Robert M. May

Author(s):  
Pavel Kikin ◽  
Alexey Kolesnikov ◽  
Alexey Portnov ◽  
Denis Grischenko

The state of ecological systems, along with their general characteristics, is almost always described by indicators that vary in space and time, which leads to a significant complication of constructing mathematical models for predicting the state of such systems. One of the ways to simplify and automate the construction of mathematical models for predicting the state of such systems is the use of machine learning methods. The article provides a comparison of traditional and based on neural networks, algorithms and machine learning methods for predicting spatio-temporal series representing ecosystem data. Analysis and comparison were carried out among the following algorithms and methods: logistic regression, random forest, gradient boosting on decision trees, SARIMAX, neural networks of long-term short-term memory (LSTM) and controlled recurrent blocks (GRU). To conduct the study, data sets were selected that have both spatial and temporal components: the values of the number of mosquitoes, the number of dengue infections, the physical condition of tropical grove trees, and the water level in the river. The article discusses the necessary steps for preliminary data processing, depending on the algorithm used. Also, Kolmogorov complexity was calculated as one of the parameters that can help formalize the choice of the most optimal algorithm when constructing mathematical models of spatio-temporal data for the sets used. Based on the results of the analysis, recommendations are given on the application of certain methods and specific technical solutions, depending on the characteristics of the data set that describes a particular ecosystem


2021 ◽  
Vol 143 (11) ◽  
Author(s):  
Zeeshan Tariq ◽  
Mohamed Mahmoud ◽  
Abdulazeez Abdulraheem

Abstract Pressure–volume–temperature (PVT) properties of crude oil are considered the most important properties in petroleum engineering applications as they are virtually used in every reservoir and production engineering calculation. Determination of these properties in the laboratory is the most accurate way to obtain a representative value, at the same time, it is very expensive. However, in the absence of such facilities, other approaches such as analytical solutions and empirical correlations are used to estimate the PVT properties. This study demonstrates the combined use of two machine learning (ML) technique, viz., functional network (FN) coupled with particle swarm optimization (PSO) in predicting the black oil PVT properties such as bubble point pressure (Pb), oil formation volume factor at Pb, and oil viscosity at Pb. This study also proposes new mathematical models derived from the coupled FN-PSO model to estimate these properties. The use of proposed mathematical models does not need any ML engine for the execution. A total of 760 data points collected from the different sources were preprocessed and utilized to build and train the machine learning models. The data utilized covered a wide range of values that are quite reasonable in petroleum engineering applications. The performances of the developed models were tested against the most used empirical correlations. The results showed that the proposed PVT models outperformed previous models by demonstrating an error of up to 2%. The proposed FN-PSO models were also compared with other ML techniques such as an artificial neural network, support vector regression, and adaptive neuro-fuzzy inference system, and the results showed that proposed FN-PSO models outperformed other ML techniques.


Author(s):  
Max A. Little

Statistical machine learning and signal processing are topics in applied mathematics, which are based upon many abstract mathematical concepts. Defining these concepts clearly is the most important first step in this book. The purpose of this chapter is to introduce these foundational mathematical concepts. It also justifies the statement that much of the art of statistical machine learning as applied to signal processing, lies in the choice of convenient mathematical models that happen to be useful in practice. Convenient in this context means that the algebraic consequences of the choice of mathematical modeling assumptions are in some sense manageable. The seeds of this manageability are the elementary mathematical concepts upon which the subject is built.


Sign in / Sign up

Export Citation Format

Share Document