Improved early post-stress TC99m-sestamibi myocardial perfusion SPECT using an energy-based scatter correction method

2005 ◽  
Vol 12 (4) ◽  
pp. S124-S124 ◽  
Author(s):  
B HSU ◽  
J CASE ◽  
T BATEMAN ◽  
S CULLOM
2007 ◽  
Vol 26 (2) ◽  
pp. 77-89
Author(s):  
S. Ruiz Solís ◽  
S. Rodado Marina ◽  
Á. Soriano Castrejón ◽  
M. Cortés Romera ◽  
V.M. Poblete García ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Tuija Kangasmaa ◽  
Jyrki Kuikka ◽  
Antti Sohlberg

Simultaneous Tl-201/Tc-99m dual isotope myocardial perfusion SPECT is seriously hampered by down-scatter from Tc-99m into the Tl-201 energy window. This paper presents and optimises the ordered-subsets-expectation-maximisation-(OS-EM-) based reconstruction algorithm, which corrects the down-scatter using an efficient Monte Carlo (MC) simulator. The algorithm starts by first reconstructing the Tc-99m image with attenuation, collimator response, and MC-based scatter correction. The reconstructed Tc-99m image is then used as an input for an efficient MC-based down-scatter simulation of Tc-99m photons into the Tl-201 window. This down-scatter estimate is finally used in the Tl-201 reconstruction to correct the crosstalk between the two isotopes. The mathematical 4D NCAT phantom and physical cardiac phantoms were used to optimise the number of OS-EM iterations where the scatter estimate is updated and the number of MC simulated photons. The results showed that two scatter update iterations and 105 simulated photons are enough for the Tc-99m and Tl-201 reconstructions, whereas 106 simulated photons are needed to generate good quality down-scatter estimates. With these parameters, the entire Tl-201/Tc-99m dual isotope reconstruction can be accomplished in less than 3 minutes.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Koichi Okuda ◽  
Kenichi Nakajima ◽  
Hiroto Yoneyama ◽  
Takayuki Shibutani ◽  
Masahisa Onoguchi ◽  
...  

AbstractThe corrections of photon attenuation, scatter, and depth-dependent blurring improve image quality in myocardial perfusion single-photon emission computed tomography (SPECT) imaging; however, the combined corrections induce artifacts. Here, we present the single correction method of depth-dependent blurring and its impact for myocardial perfusion distribution in phantom and clinical studies. The phantom and clinical patient images were acquired with two conditions: circular and noncircular orbits of gamma cameras yielded constant and variable depth-dependent blurring, respectively. An iterative reconstruction with the correction method of depth-dependent was used to reconstruct the phantom and clinical patient images. We found that the single correction method improved the robustness of phantom images whether the images contained constant or variable depth-dependent blurring. The myocardial perfusion databases generated from 72 normal patients exhibited uniform perfusion distribution of whole myocardium. In summary, the single correction method of depth-dependent blurring with iterative reconstruction is helpful for myocardial perfusion SPECT.


2011 ◽  
Vol 32 (11) ◽  
pp. 1040-1045 ◽  
Author(s):  
Tuija S. Kangasmaa ◽  
Jyrki T. Kuikka ◽  
Esko J. Vanninen ◽  
Hanna M. Mussalo ◽  
Tomi P. Laitinen ◽  
...  

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