scholarly journals Dengue control measures via cytoplasmic incompatibility and modern programming tools

2021 ◽  
Vol 21 ◽  
pp. 103819
Author(s):  
Ayesha Sohail ◽  
Mehwish Iftikhar ◽  
Robia Arif ◽  
Hijaz Ahmad ◽  
Khaled A. Gepreel ◽  
...  
Keyword(s):  
Cytoplasmic Incompatibility ◽  
Control Measures ◽  
Programming Tools ◽  
Dengue Control

scholarly journals Recent advances in understanding dengue

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 78 ◽  
Author(s):  
Sophie Yacoub ◽  
Juthathip Mongkolsapaya ◽  
Gavin Screaton
Keyword(s):  
Severe Disease ◽  
Current Treatment ◽  
Control Measures ◽  
Future Research ◽  
Recent Advances ◽  
Immune Mediated ◽  
Wide Range ◽  
Viral Structure ◽  
Dengue Control ◽  
Epitope Binding

Dengue is an emerging threat to billions of people worldwide. In the last 20 years, the incidence has increased four-fold and this trend appears to be continuing. Caused by one of four viral serotypes, dengue can present as a wide range of clinical phenotypes with the severe end of the spectrum being defined by a syndrome of capillary leak, coagulopathy, and organ impairment. The pathogenesis of severe disease is thought to be in part immune mediated, but the exact mechanisms remain to be defined. The current treatment of dengue relies on supportive measures with no licensed therapeutics available to date. There have been recent advances in our understanding of a number of areas of dengue research, of which the following will be discussed in this review: the drivers behind the global dengue pandemic, viral structure and epitope binding, risk factors for severe disease and its pathogenesis, as well as the findings of recent clinical trials including therapeutics and vaccines. We conclude with current and future dengue control measures and key areas for future research.

scholarly journals Dengue control in Ribeirão Preto, São Paulo, Brazil

1998 ◽  
Vol 14 (suppl 2) ◽  
pp. S123-S128 ◽  
Author(s):  
Afonso Dinis Costa Passos ◽  
Eugênia Maria Silveira Rodrigues ◽  
Amaury Lelis Dal-Fabbro
Keyword(s):  
Sao Paulo ◽  
Control Measures ◽  
Type I ◽  
São Paulo ◽  
Public Agencies ◽  
Popular Participation ◽  
Breeding Sites ◽  
Preventive Work ◽  
Dengue Control ◽  
The City

Following an epidemic of type I dengue in late 1990, the municipality of Ribeirão Preto (State of São Paulo, Brazil) assumed direct responsibility for the control of Aedes aegypti larvae. Control activities are presented in this report and are based on popular participation and environmental management. Massive use of the communications media, participation by schoolchildren, constant contact with the population, and integration of various public agencies are the program's priorities. Although the drop in the number of susceptibles may have played a role in the reduction of cases after the initial epidemic, the intense preventive campaign certainly helped quell the disease in the city, since changes were observed in the behavior of the population towards potential breeding sites. The occurrence of new cases in recent years appears to be related to greater circulation of the virus in both the State of São Paulo and Brazil as a whole, indicating the need for control measures at the national and continental level, without which it will be difficult to maintain low transmission rates, even in areas submitted to intense preventive work.

scholarly journals Dengue Control Measures in Tagbilaran City, Bohol, Philippines

2020 ◽  
Author(s):  
Edgar E. Acosta ◽  
Mauro Allan Padua Amparado
Keyword(s):  
Family Income ◽  
Action Plan ◽  
Control Program ◽  
Signs And Symptoms ◽  
Control Measures ◽  
Protection Measures ◽  
Early Signs ◽  
Dengue Control ◽  
Self Protection ◽  
Search And Destroy

The study determined the implementation of the Department of Health’s Dengue control measures in Tagbilaran City, Bohol, Philippines. It specifically sought to answer the following questions: profile of the respondents in terms of age, highest educational attainment, family income, and number of children 12 years old and below; level of implementation of Dengue Control Program in terms of search and destroy, and self-protection measures; and perceptions on Dengue control measures in terms of seeking early consultation and fogging. This study utilized the descriptive-correlational design. There were 398 respondents who were involved in this study. They were mothers, 18 years old and above and from the 15 barangays of Tagbilaran City, Bohol. A modified researcher-made questionnaire was used to collect data. This study is a replication of the study of Rufo & Amparado on Dengue control measures conducted in the City of Naga, Cebu, Philippines (2017). The results revealed that majority of the respondents belonged to the age range of 26 to 45 years old, college students, has an income range of 5,000 to 10,000 Philippine pesos per month and have two children below 12 years old. In terms of search and destroy, and self-protection measures, mothers have strong implementation on covering water containers with tight lid as well as storing properly and discarding non-essential containers like bottles, cans, jars and tires. Moderate implementation was on changing flowers from water vases, and cleaning the vicinity from drains and garbage. Mothers have poor implementation measures on the use of mosquito repellants, mosquito nets at daytime, and the use of household insecticide aerosol, insecticide vaporizers, or mosquito coils. Most of them recognized the early signs and symptoms of dengue such as severe headache and fever. Nearly all mothers brought their child to the nearest health facility as part of their initial management every time their child experiences fever. Most of them do not agree on the use of fogging measures to be done against dengue control. There were significant relationships between the profile and: search and destroy measures; self-protection measures; and knowledge on the early signs and symptoms of dengue. In conclusion, dengue prevention and control in the community have not been fully implemented because of the lack of community-based, integrated health control program which are sustainable and health-enhancing. Recommendations include replicating the study and the implementation of the proposed action plan. Recommended citation: Acosta, E. E. & Amparado, M. A. P. (2017). Dengue Control Measures in Tagbilaran City, Bohol, Philippines. Journal of Research in Nursing, 3(1), 20-29.Reference: Rufo, F. J. M. & Amparado, M. A. P. (2017). Implementation of Dengue Control Measures in City of Naga, Cebu, Philippines. IAMURE International Journal of Social Sciences, 19(1), 58-76.

scholarly journals Analytical report of the 2016 dengue outbreak in Córdoba city, Argentina

2017 ◽  
Author(s):  
Camilo Rotela ◽  
Laura Lopez ◽  
María Frías Céspedes ◽  
Gabriela Barbas ◽  
Andrés Lighezzolo ◽  
...  
Keyword(s):  
Temporal Analysis ◽  
Control Measures ◽  
Remotely Sensed Data ◽  
Dengue Outbreak ◽  
High Incidence ◽  
Dengue Outbreaks ◽  
Spatio Temporal ◽  
The 1960S ◽  
Dengue Control ◽  
The City

After elimination of the Aedes aegypti vector in South America in the 1960s, dengue outbreaks started to reoccur during the 1990s; strongly in Argentina since 1998. In 2016, Córdoba City had the largest dengue outbreak in its history. In this article we report this outbreak including spatio-temporal analysis of cases and vectors in the city. A total of 653 dengue cases were recorded by the laboratory-based dengue surveillance system and georeferenced by their residential addresses. Case maps were generated from the epidemiological week 1 (beginning of January) to week 19 (mid-May). Dengue outbreak temporal evolution was analysed globally and three specific, high-incidence zones were detected using Knox analysis to characterising its spatio-temporal attributes. Field and remotely sensed data were collected and analysed in real time and a vector presence map based on the MaxEnt approach was generated to define hotspots, towards which the pesticide- based strategy was then targeted. The recorded pattern of cases evolution within the community suggests that dengue control measures should be improved.

scholarly journals A review of dengue diagnostics and implications for surveillance and control

2019 ◽  
Vol 113 (11) ◽  
pp. 653-660 ◽  
Author(s):  
Nader Raafat ◽  
Stuart D Blacksell ◽  
Richard J Maude
Keyword(s):  
Disease Surveillance ◽  
Dengue Infection ◽  
Signs And Symptoms ◽  
Diagnostic Methods ◽  
Control Measures ◽  
Polymerase Chain ◽  
Dengue Diagnostics ◽  
Dengue Control ◽  
Age Range ◽  
And Control

Abstract Dengue is the world’s most common arboviral infection, with almost 4 billion people estimated to be living at risk of dengue infection. A recently introduced vaccine is currently recommended only for seropositive individuals in a restricted age range determined by transmission intensity. With no effective dengue vaccine for the general population or any antiviral therapy, dengue control continues to rely heavily on vector control measures. Early and accurate diagnosis is important for guiding appropriate management and for disease surveillance to guide prompt dengue control interventions. However, major uncertainties exist in dengue diagnosis and this has important implications for all three. Dengue can be diagnosed clinically against predefined lists of signs and symptoms and by detection of dengue-specific antibodies, non-structural 1 antigen or viral RNA by reverse transcriptase–polymerase chain reaction. All of these methods have their limitations. This review aims to describe and quantify the advantages, uncertainties and variability of the various diagnostic methods used for dengue and discuss their implications and applications for dengue surveillance and control.

scholarly journals ‘Dengue: Australia’s other pandemic’

2009 ◽  
Vol 30 (4) ◽  
pp. 114 ◽  
Author(s):  
Scott A Rithchie
Keyword(s):  
Urban Areas ◽  
Management Plan ◽  
Control Measures ◽  
Source Reduction ◽  
Management Framework ◽  
Queensland Health ◽  
Dengue Transmission ◽  
Rapid Transmission ◽  
Dengue Control ◽  
Fever Management

Pandemic dengue arrived in Australia in 2008-09. A large epidemic of Dengue Virus 3 (DENV-3) affected much of north Queensland, with over 900 cases and one death, in Cairns. This was accompanied by 18 imported viremic dengue cases into north Queensland from January to May 2009 and outbreaks of DENV-1, -2 and -4 in Townsville, Cairns and Innisfail, respectively. The virus was unique, with apparently shorter incubation periods, resulting in rapid transmission that exceeded the capacity of Queensland Health?s five-man dengue control team. Furthermore, potential pesticide resistance reduced the efficacy of some control measures. This unprecedented level of dengue activity has highlighted problems with the Dengue Fever Management Plan (DFMP), forcing the implementation of new interventions to control the epidemic. These included adoption of the Emergency Management Framework that allowed access to resources beyond those budgeted. New emergency teams conducted interior residual spraying and treating of containers in yards with methoprene and this was supplemented by SES volunteers, who delivered cans of surface spray to residents. This wide-ranging approach rapidly reduced transmission. Nonetheless, the presence of high populations of Ae. aegypti, that sustained epidemic transmission in much of north Queensland, highlights the need for the expansion of the DFMP to fund a comprehensive source reduction campaign. The incursion and establishment of the vectors Ae. aegypti and Ae. albopictus into eastern urban areas could dramatically increase the range of dengue transmission in Australia. Novel vector control measures, such as the use of life-shortening Wolbachia, offer the potential to eliminate dengue transmission in the future.

scholarly journals Awareness of dengue and practice of dengue control measures among urban population in Tamil Nadu, India

2018 ◽  
Vol 5 (2) ◽  
pp. 795
Author(s):  
Varun Kumar T. ◽  
Vijay Pandian M. ◽  
Swaminathan P. ◽  
Ravi Kumar T.
Keyword(s):  
Urban Population ◽  
Tamil Nadu ◽  
Mosquito Control ◽  
Dengue Infection ◽  
Control Measures ◽  
Health Campaigns ◽  
Cross Sectional ◽  
Aedes Mosquitoes ◽  
Dengue Control ◽  
Study Participants

Background: The dengue infection has become endemic in India as a result of changing environmental conditions and lack of awareness among the public. So, the present study was conducted with the objectives of studying the awareness of dengue and dengue control practices among urban population in Coimbatore, Tamil Nadu.Methods: The study was of cross sectional design conducted in the fever clinic of Government Medical College and ESI Hospital, Coimbatore, Tamil Nadu. Systemic random sampling was done to select the study participants. A pre-tested, pre-validated semi-structured questionnaire was used to obtain data was obtained from 270 individuals during August to November 2017.Results: Among the study participants, 254 (94.1%) had heard of dengue. Among them, 145 (53.7%) correctly identified the symptoms of dengue, 221 (81.6%) correctly responded that the dengue is transmitted by Aedes mosquitoes and 82 (30.4%) had correct knowledge about Aedes mosquito breeding places. Younger age group individuals and those with higher education had significantly better awareness about mosquito control measures (p<0.005).Conclusions: Majority of the study population was aware about dengue, only half of them knew about the symptoms of dengue and only one-third correctly knew about breeding habitats of Aedes mosquitoes. Therefore, already functioning health campaigns should ensure that the knowledge acquired is put into practice. 

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