Feature selection of infrared spectra analysis with convolutional neural network

Author(s):  
Jingjing Xia ◽  
Jixiong Zhang ◽  
Yanmei Xiong ◽  
Shungeng Min
2021 ◽  
Vol 11 (11) ◽  
pp. 5235
Author(s):  
Nikita Andriyanov

The article is devoted to the study of convolutional neural network inference in the task of image processing under the influence of visual attacks. Attacks of four different types were considered: simple, involving the addition of white Gaussian noise, impulse action on one pixel of an image, and attacks that change brightness values within a rectangular area. MNIST and Kaggle dogs vs. cats datasets were chosen. Recognition characteristics were obtained for the accuracy, depending on the number of images subjected to attacks and the types of attacks used in the training. The study was based on well-known convolutional neural network architectures used in pattern recognition tasks, such as VGG-16 and Inception_v3. The dependencies of the recognition accuracy on the parameters of visual attacks were obtained. Original methods were proposed to prevent visual attacks. Such methods are based on the selection of “incomprehensible” classes for the recognizer, and their subsequent correction based on neural network inference with reduced image sizes. As a result of applying these methods, gains in the accuracy metric by a factor of 1.3 were obtained after iteration by discarding incomprehensible images, and reducing the amount of uncertainty by 4–5% after iteration by applying the integration of the results of image analyses in reduced dimensions.


2019 ◽  
Author(s):  
Nguyen P. Nguyen ◽  
Jacob Gotberg ◽  
Ilker Ersoy ◽  
Filiz Bunyak ◽  
Tommi White

AbstractSelection of individual protein particles in cryo-electron micrographs is an important step in single particle analysis. In this study, we developed a deep learning-based method to automatically detect particle centers from cryoEM micrographs. This is a challenging task because of the low signal-to-noise ratio of cryoEM micrographs and the size, shape, and grayscale-level variations in particles. We propose a double convolutional neural network (CNN) cascade for automated detection of particles in cryo-electron micrographs. Particles are detected by the first network, a fully convolutional regression network (FCRN), which maps the particle image to a continuous distance map that acts like a probability density function of particle centers. Particles identified by FCRN are further refined (or classified) to reduce false particle detections by the second CNN. This approach, entitled Deep Regression Picker Network or “DRPnet”, is simple but very effective in recognizing different grayscale patterns corresponding to 2D views of 3D particles. Our experiments showed that DRPnet’s first CNN pretrained with one dataset can be used to detect particles from a different datasets without retraining. The performance of this network can be further improved by re-training the network using specific particle datasets. The second network, a classification convolutional neural network, is used to refine detection results by identifying false detections. The proposed fully automated “deep regression” system, DRPnet, pretrained with TRPV1 (EMPIAR-10005) [1], and tested on β-galactosidase (EMPIAR-10017) [2] and β-galactosidase (EMPIAR-10061) [3], was then compared to RELION’s interactive particle picking. Preliminary experiments resulted in comparable or better particle picking performance with drastically reduced user interactions and improved processing time.


2021 ◽  
Vol 9 (24) ◽  
pp. 1752-1752
Author(s):  
Xin Zhou ◽  
Xuying Wang ◽  
Xianhong Li ◽  
Yao Zhang ◽  
Ying Liu ◽  
...  

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