Imperatorin attenuates cardiac remodelling and dysfunction in high-fat/high-fructose diet-fed rats by modulating oxidative stress, inflammation, and Nrf-2 expression

2022 ◽  
pp. 101728
Author(s):  
Patoomporn Prasartthong ◽  
Poungrat Pakdeechote ◽  
Putcharawipa Maneesai ◽  
Sariya Meephat ◽  
Siwayu Rattanakanokchai ◽  
...  
2021 ◽  
Author(s):  
Rodrigo Cardoso ◽  
Luiza Dias Moreira ◽  
Mirian Costa ◽  
Renata Celi Lopes Toledo ◽  
Mariana Grancieri ◽  
...  

The aim of this study was to evaluate the effect of green and black tea kombuchas consumption on adiposity, lipid metabolism, liver steatosis, oxidative stress, and inflammation in Wistar rats...


Author(s):  
PRIYA CHANDRASEKARAN SATHIYA ◽  
RAMACHANDRAN VIDHYA ◽  
KALIVARATHAN JAGAN ◽  
CARANI VENKATRAMAN ANURADHA

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Kanokwan Jarukamjorn ◽  
Nattharat Jearapong ◽  
Charinya Pimson ◽  
Waranya Chatuphonprasert

Excessive fat liver is an important manifestation of nonalcoholic fatty liver disease (NAFLD), associated with obesity, insulin resistance, and oxidative stress. In the present study, the effects of a high-fat, high-fructose diet (HFFD) on mRNA levels and activities of the antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were determined in mouse livers and brains. The histomorphology of the livers was examined and the state of nonenzymatic reducing system was evaluated by measuring the glutathione system and the lipid peroxidation. Histopathology of the liver showed that fat accumulation and inflammation depended on the period of the HFFD-consumption. The levels of mRNA and enzymatic activities of SOD, CAT, and GPx were raised, followed by the increases in malondialdehyde levels in livers and brains of the HFFD mice. The oxidized GSSG content was increased while the total GSH and the reduced GSH were decreased, resulting in the increase in the GSH/GSSG ratio in both livers and brains of the HFFD mice. These observations suggested that liver damage and oxidative stress in the significant organs were generated by continuous HFFD-consumption. Imbalance of antioxidant condition induced by long-term HFFD-consumption might increase the risk and progression of NAFLD.


2021 ◽  
Vol 99 ◽  
pp. 103207
Author(s):  
Jaqueline Maciel Vieira Theodoro ◽  
Oscar David Medina Martinez ◽  
Mariana Grancieri ◽  
Renata Celi Lopes Toledo ◽  
Amanda M. Dias Martins ◽  
...  

Lipids ◽  
2019 ◽  
Vol 54 (1) ◽  
pp. 81-97 ◽  
Author(s):  
Christine Feillet-Coudray ◽  
Gilles Fouret ◽  
Claire Vigor ◽  
Béatrice Bonafos ◽  
Bernard Jover ◽  
...  

2019 ◽  
Vol 55 ◽  
pp. 117-125 ◽  
Author(s):  
Kanokwan Jarukamjorn ◽  
Waranya Chatuphonprasert ◽  
Nattharat Jearapong ◽  
Charatda Punvittayagul ◽  
Rawiwan Wongpoomchai

2021 ◽  
Author(s):  
Oscar David Medina Martinez ◽  
Jaqueline Maciel Vieira Theodoro ◽  
Mariana Grancieri ◽  
Renata Celi Lopes Toledo ◽  
Frederico Barros ◽  
...  

This study aimed to evaluate the effect of dry heated sorghum BRS 305 hybrid flour, as a rich source of resistant starch and tannin, on inflammation and oxidative stress in...


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