Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer

Plants are generally measured as origin of natural drugs and are extensively used in herbal formulations. Muntingia calabura (Muntingeaceae) is indigenous to Central America and Southern Mexico It is abundantly disseminated throughout Asian countries especially in India. The present research was done on the isolation, pharmacological study of the isolated compounds derived from root heart wood and bark of the root of Muntingia calabura. For this study, six compounds were taken into account and later it was divided into two categories as flavonoids and chalcones. The isolated compounds were further screened for their attributed pharmacological traits. All the compounds screened noticed to possess significant medicinal properties.

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Salvianolic Acids: Potential Source of Natural Drugs for the Treatment of Fibrosis Disease and Cancer

Frontiers in Pharmacology ◽

10.3389/fphar.2019.00097 ◽

2019 ◽

Vol 10 ◽

Cited By ~ 20

Author(s):

Lunkun Ma ◽

Liling Tang ◽

Qian Yi

Keyword(s):

Potential Source ◽

Salvianolic Acids ◽

Natural Drugs

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Betelvine (Piper betle L.): A potential source for oral care

Current Botany ◽

10.25081/cb.2020.v11.6130 ◽

2020 ◽

pp. 87-92

Author(s):

U. Chowdhury ◽

P.K. Baruah

Keyword(s):

Oral Cavity ◽

Chlorogenic Acid ◽

Natural Product ◽

Past History ◽

Oral Care ◽

Piper Betle ◽

Traditional Uses ◽

Potential Source ◽

History Of

Piper betle L. (betelvine) is a valuable crop that is widely used as masticatory and with a long past history of varied traditional uses. Betelvine possesses numerous phytochemicals with important pharmacological attributes. Active molecules such as Fluoride, Eugenol, Hydroxylchavicol, Chlorogenic acid etc. present in betelvine with potent antibacterial, antifungal as well as anti-carcinogenic properties signify tremendous prospective of the plant for the formulation of natural product based drugs for maintaining hygiene and cure of diseases in the oral cavity.

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How SIMS microscopy can be used in medicine

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100132649 ◽

1992 ◽

Vol 50 (2) ◽

pp. 1602-1603

Author(s):

Philippe Fragu

Keyword(s):

Mass Spectrometry ◽

Biomedical Applications ◽

Secondary Ion Mass Spectrometry ◽

Chemical Elements ◽

Biological Applications ◽

The Past ◽

Potential Source ◽

Secondary Ion ◽

Chemical Integrity ◽

Scientific Endeavour

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.

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Tobacco Mosaic Virus-Infected Tissue

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100119375 ◽

1985 ◽

Vol 43 ◽

pp. 510-511

Author(s):

Egbert W. Henry

Keyword(s):

Nicotiana Tabacum ◽

Tobacco Mosaic Virus ◽

Chlorogenic Acid ◽

Mosaic Virus ◽

Host Resistance ◽

Oxidative Metabolism ◽

Leaf Tissue ◽

Vein Clearing ◽

Basal Septum ◽

Concentration Levels

Tobacco mosaic virus (TMV) infection has been studied in several investigations of Nicotiana tabacum leaf tissue. Earlier studies have suggested that TMV infection does not have precise infective selectivity vs. specific types of tissues. Also, such tissue conditions as vein banding, vein clearing, liquification and suberization may result from causes other than direct TMV infection. At the present time, it is thought that the plasmodesmata, ectodesmata and perhaps the plasmodesmata of the basal septum may represent the actual or more precise sites of TMV infection.TMV infection has been implicated in elevated levels of oxidative metabolism; also, TMV infection may have a major role in host resistance vs. concentration levels of phenolic-type enzymes. Therefore, enzymes such as polyphenol oxidase, peroxidase and phenylalamine ammonia-lyase may show an increase in activity in response to TMV infection. It has been reported that TMV infection may cause a decrease in o-dihydric phenols (chlorogenic acid) in some tissues.

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