scholarly journals An overlooked route of inhalation exposure to tap water constituents for children and adults: Aerosolized aqueous minerals from ultrasonic humidifiers

2020 ◽  
Vol 9 ◽  
pp. 100060 ◽  
Author(s):  
Wenchuo Yao ◽  
Daniel L. Gallagher ◽  
Andrea M. Dietrich
Keyword(s):  
Tap Water ◽  
Inhalation Exposure ◽  
Water Constituents

scholarly journals Multipathway risk assessment of trihalomethane exposure in drinking water of Lebanon

2007 ◽  
Vol 5 (4) ◽  
pp. 511-522 ◽  
Author(s):  
Lucy Semerjian ◽  
John Dennis
Keyword(s):  
Cancer Risk ◽  
Tap Water ◽  
Inhalation Exposure ◽  
Dermal Absorption ◽  
Cancer Risks ◽  
Oral Ingestion ◽  
Lifetime Cancer Risk ◽  
Exposed Population ◽  
Total Cancer ◽  
Risk Of Cancer

The toxicological risks and lifetime cancer risks of trihalomethanes through oral ingestion, dermal absorption, and inhalation exposure from tap water in selected regions in Lebanon are estimated. Existing trihalomethane concentrations do not pose any non-carcinogenic and developmental risks in the exposed population via oral ingestion. Among the three pathways, residents have a higher risk of cancer through oral ingestion than through the other two pathways. The lifetime cancer risk through oral ingestion for dibromochloromethane makes the highest contribution to total risks, followed by bromodichloromethane, bromoform, and chloroform. The total multipathway cancer risk analysis suggests that no cancer risks exist during the summer and winter seasons; however, in the spring the total cancer risks exceeds the USEPA acceptable level of 10−6 by a factor of 10.7.

Toxic effects of inhaled DMMP on the kidneys of Fischer-344 rats

1987 ◽  
Vol 45 ◽  
pp. 880-881
Author(s):  
D.R. Mattie ◽  
C.J. Hixson
Keyword(s):  
Left Kidney ◽  
Inhalation Exposure ◽  
Electron Microscopic Examination ◽  
Exposure Period ◽  
Male Rats ◽  
Continuous Exposure ◽  
Fischer 344 Rats ◽  
Electron Microscopic ◽  
Thin Sections ◽  
Fischer 344

Dimethylmethylphosphonate (DMMP) is a simple organophosphate used industrially as a flame retardant and to lower viscosity in polyester and epoxy resins. The military considered the use of DMMP as a nerve gas simulant. Since military use of DMMP involved exposure by inhalation, there was a need for a subchronic inhalation exposure to DMMP to fully investigate its toxic potential.Male Fischer-344 rats were exposed to 25 ppm or 250 ppm DMMP vapor on a continuous basis for 90 days. An equal number of control rats were sham-exposed. Following the 90-day continuous exposure period, 15 male rats were sacrificed from each group. Two rats from each group had the left kidney perfused for electron microscopic examination. The kidneys were perfused from a height of 150 cm water with 1% glutaraldehyde in Sorensen's 0.1M phosphate buffer pH 7.2. An additional kidney was taken from a rat in each group and fixed by immersion in 2.5% glutaraldehyde and 2% paraformaldehyde in 0.1M cacodylate buffer pH 7.4. A portion of the 9 kidneys collected for electron microscopy were processed into Epon 812. Thin sections, stained with uranyl acetate and lead citrate, were examined with a JEOL 100B Transmission Electron Microscope. Microvilli height was measured on photographs of the cells of proximal tubules. This data, along with morphologic features of the cells, allows the proximal convoluted tubules (PCT) to be identified as being S1, S2, or S3 segment PCT.

Evaluation of hippocampus in rhesus monkeys after chronic (1-year) inhalation exposure to marijuana: I. Electron microscopy

1990 ◽  
Vol 48 (3) ◽  
pp. 398-399
Author(s):  
A.M. Andrews ◽  
S.W. Wilson ◽  
A.C. Scallet ◽  
S.F. Ali ◽  
J. Bailey ◽  
...  
Keyword(s):  
Synaptic Vesicles ◽  
Rhesus Monkeys ◽  
Low Dose ◽  
Inhalation Exposure ◽  
Synaptic Cleft ◽  
High Dose ◽  
Withdrawal Time ◽  
Treatment Groups ◽  
Ultrastructural Evidence ◽  
Male Rhesus

Exposure of rhesus monkeys (Macaca mulatta) to marijuana via inhalation or to intravenous delta-9-tetrahydrocannabinol (THC), reportedly caused ultrastructural evidence of increased synaptic width. Chronic marijuana smoke in a single rhesus monkey examined after a six month withdrawal time caused ultrastructure changes in the septal, hippocampal and amygdala regions; the synaptic cleft was widened, electron opaque material was found in the cleft and in the pre- and postsynaptic regions, with some clumping of the synaptic vesicles. The objective of our study was to assess neuropathological alterations produced by chronic inhalation of marijuana smoke.Nineteen male rhesus monkeys, 3-5 years of age and weighing 3-8 kg, were divided into four treatment groups: a) sham control, b) placebo smoke (7 days/ week) c) low dose marijuana (2 times/week with 5 days/week sham) and d) high dose marijuana (7 times/week). A smoke exposure consisted of smoke from one cigarette (2.6% THC) burned down to 10 mm butt length. Smoke was administered via smoke generator (ADL II, Arthur D. Little, Inc. Cambridge, MA) and nose-mouth only masks (local production) equipped with one-way valves.

Evaluating Performance Effects of Low-Level Inhalation Exposure to Nerve Agents in Rats

2004 ◽  
Author(s):  
Raymond F. Genovese ◽  
◽  
Sara J. Shippee ◽  
Jessica Bonnell ◽  
Bernard J. Benton ◽  
...  
Keyword(s):  
Inhalation Exposure ◽  
Nerve Agents ◽  
Low Level ◽  
Performance Effects

217. Design and Operation of a Popcorn Butter Flavoring Inhalation Exposure System

2002 ◽  
Author(s):  
T. Goldsmith ◽  
D. Frazer ◽  
W. McKinney ◽  
W. Jones
Keyword(s):  
Inhalation Exposure ◽  
Exposure System

STUDIES IN THE SUPPOSED GOITROGENOUS EFFECT OF TAP WATER IN HELSINKI

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 630-636
Author(s):  
F.-E. Krusius ◽  
P. Peltola
Keyword(s):  
Tap Water ◽  
Physiological Saline ◽  
Normal Weight ◽  
The Body ◽  
Iodine Uptake ◽  
Redistilled Water ◽  
Detectable Difference ◽  
Term Administration ◽  
Long Term Experiment

ABSTRACT The study reported here was performed in order to examine the tap water of Helsinki for its alleged goitrogenous effect. In a short-term, 24-hour experiment with rats, kept on an iodine-poor diet, we noticed no inhibition of the 4-hour 131I uptake, as compared with that of animals receiving physiological saline instead of tap water. Two similar groups of rats receiving 1 and 2 mg of mercazole in redistilled water showed a distinct blockage of the 4-hour uptake, which proved the effect of this substance. In a long-term experiment of 5 weeks' duration there was no detectable difference in the body weight, thyroid weight and the 4-hour 131I uptake when the rats receiving tap water or distilled water to which 0.45 per cent of sodium chloride was added were compared with each other. Replacement of tap water by a 10 mg per cent solution of mercazole in redistilled water enlarged the thyroid to double its normal weight and increased the 131I uptake to approximately five times that of the controls. Thus our experiments failed to demonstrate any goitrogenous effect in the tap water of Helsinki. Changes similar to those produced by a long-term administration of mercazole, i. e. an enlargement of the thyroid and an increased thyroidal iodine uptake, have been shown to be due to milk collected from goitrous areas. The observations here reported confirm the importance of milk in the genesis of the goitre endemia of Helsinki. Attention is further called to the fact that a thyroidal enlargement combined with an increased thyroidal iodine uptake cannot always be taken as a sign of iodine deficiency because similar changes may be produced by the administration of goitrogens.

Tap Water As Irrigation Fluid in Percutaneous Nephrolithotomy

2012 ◽  
Vol 3 (4) ◽  
pp. 1-2
Author(s):  
* Dr. Prashant Hansraj Salvi ◽  
◽  
Dr.Ketan Vartak ◽  
Dr. Sudhir Shinde
Keyword(s):  
Percutaneous Nephrolithotomy ◽  
Tap Water ◽  
Irrigation Fluid

Relationship between availability of basic amenities and proportion of Slum population in Maharashtra

2020 ◽  
Vol 6 (11) ◽  
pp. 1343-1354
Author(s):  
Dr. Sakreen Hasan
Keyword(s):  
Drinking Water ◽  
Tap Water ◽  
Policy Implications ◽  
Class I ◽  
Urban Centers ◽  
The Sustainable Development ◽  
Closed Drainage ◽  
The People ◽  
Basic Infrastructure ◽  
Slum Population

The urban centers offering diverse employment opportunities and means of livelihood are the main centers of attraction for migration. But the availability of infrastructure is low to accommodate the invariably growing population. The access to basic amenities like electricity, drinking water, toilet facility, wastewater outlet and clean fuel are critical determinants of quality of urbanization. And if it lacks, then it would facilitates the growth of slum.  In this paper it being tried to capture the interdependent relationship between basic amenities and slum population residing in the class I towns in Maharashtra; largest slum populated state of India. As the slum is all about the situation or condition in which the people of medium and lower strata are living. A detailed analysis of proportion of slum population and availability of amenities which includes good housing condition, treated tap water as the source of drinking water, electricity as the source of lightning, households having latrine and bathing facility within the premises, waste water outlet connected to closed drainage, and households availing the banking facilities. This may be a limitation of the study that only these indicators have been taken to assess the availability of amenities and to calculate the amenity index of class I towns of the state of Maharashtra. To achieve the sustainable development goal (Sustainable cities and communities), we have to control the growth of slum population and to combat the formation of slum; we have to analyze the situation of basic infrastructure provided in urban centers. Amenities and slum population has policy implications as to reduce the slum population, provide basic amenities to the households which will improve their standard of living and ultimately lead to reduction in growth of slum and check the future slum formation.

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