Comparison of Plethysmographic and Helium Dilution Lung Volumes: Which Is Best for COPD?

2011 ◽  
Vol 2011 ◽  
pp. 42-43
Author(s):  
J.R. Maurer
Keyword(s):  
Lung Volumes ◽  
Helium Dilution

A pilot comparison of helium dilution and plethysmographic lung volumes to assess the impact of a long-acting bronchodilator on lung hyperinflation in COPD

2009 ◽  
Vol 22 (6) ◽  
pp. 522-525 ◽  
Author(s):  
Mario Cazzola ◽  
Paola Rogliani ◽  
Giacomo Curradi ◽  
Andrea Segreti ◽  
Chiara Ciaprini ◽  
...  
Keyword(s):  
Lung Volumes ◽  
Lung Hyperinflation ◽  
Helium Dilution ◽  
Long Acting ◽  
The Impact

scholarly journals Comparison of Plethysmographic and Helium Dilution Lung Volumes

CHEST Journal ◽  
2010 ◽  
Vol 137 (5) ◽  
pp. 1108-1115 ◽  
Author(s):  
Carl R. O'Donnell ◽  
Alexander A. Bankier ◽  
Leopold Stiebellehner ◽  
John J. Reilly ◽  
Robert Brown ◽  
...  
Keyword(s):  
Lung Volumes ◽  
Helium Dilution

scholarly journals Multiple breath helium dilution measurement of lung volumes in adults

1998 ◽  
Vol 11 (1) ◽  
pp. 246-255 ◽  
Author(s):  
R. Brown ◽  
D.E. Leith ◽  
P.L. Enright
Keyword(s):  
Lung Volumes ◽  
Helium Dilution

Measurement of lung volumes from supine portable chest radiographs

1979 ◽  
Vol 47 (6) ◽  
pp. 1332-1335 ◽  
Author(s):  
A. L. Ries ◽  
J. L. Clausen ◽  
P. J. Friedman
Keyword(s):  
Lung Volume ◽  
Chest Radiographs ◽  
Lung Field ◽  
Regression Equations ◽  
Lung Volumes ◽  
Magnification Factors ◽  
Portable Chest ◽  
Radiographic Magnification ◽  
Helium Dilution ◽  
Gas Dilution

Lung volumes in supine nonambulatory patients are physiological parameters often difficult to measure with current techniques (plethysmograph, gas dilution). Existing radiographic methods for measuring lung volumes require standard upright chest radiographs. Accordingly, in 31 normal supine adults, we determined helium-dilution functional residual and total lung capacities and measured planimetric lung field areas (LFA) from corresponding portable anteroposterior and lateral radiographs. Low radiation dose methods, which delivered less than 10% of that from standard portable X-ray technique, were utilized. Correlation between lung volume and radiographic LFA was highly significant (r = 0.96, SEE = 10.6%). Multiple-step regressions using height and chest diameter correction factors reduced variance, but weight and radiographic magnification factors did not. In 17 additional subjects studied for validation, the regression equations accurately predicted radiographic lung volume. Thus, this technique can provide accurate and rapid measurement of lung volume in studies involving supine patients.

Transpulmonary pressures and lung mechanics with glossopharyngeal insufflation and exsufflation beyond normal lung volumes in competitive breath-hold divers

2007 ◽  
Vol 102 (3) ◽  
pp. 841-846 ◽  
Author(s):  
Stephen H. Loring ◽  
Carl R. O'Donnell ◽  
James P. Butler ◽  
Peter Lindholm ◽  
Francine Jacobson ◽  
...  
Keyword(s):  
Lung Mechanics ◽  
Normal Lung ◽  
Breath Hold ◽  
Lung Volumes ◽  
Pressure Equalization ◽  
Lung Capacity ◽  
Middle Ear Pressure ◽  
Helium Dilution ◽  
Predicted Values ◽  
Gas Volume

Throughout life, most mammals breathe between maximal and minimal lung volumes determined by respiratory mechanics and muscle strength. In contrast, competitive breath-hold divers exceed these limits when they employ glossopharyngeal insufflation (GI) before a dive to increase lung gas volume (providing additional oxygen and intrapulmonary gas to prevent dangerous chest compression at depths recently greater than 100 m) and glossopharyngeal exsufflation (GE) during descent to draw air from compressed lungs into the pharynx for middle ear pressure equalization. To explore the mechanical effects of these maneuvers on the respiratory system, we measured lung volumes by helium dilution with spirometry and computed tomography and estimated transpulmonary pressures using an esophageal balloon after GI and GE in four competitive breath-hold divers. Maximal lung volume was increased after GI by 0.13–2.84 liters, resulting in volumes 1.5–7.9 SD above predicted values. The amount of gas in the lungs after GI increased by 0.59–4.16 liters, largely due to elevated intrapulmonary pressures of 52–109 cmH2O. The transpulmonary pressures increased after GI to values ranging from 43 to 80 cmH2O, 1.6–2.9 times the expected values at total lung capacity. After GE, lung volumes were reduced by 0.09–0.44 liters, and the corresponding transpulmonary pressures decreased to −15 to −31 cmH2O, suggesting closure of intrapulmonary airways. We conclude that the lungs of some healthy individuals are able to withstand repeated inflation to transpulmonary pressures far greater than those to which they would normally be exposed.

Effect of Peritoneal Dialysis Fluid on Ventilatory Function

1981 ◽  
Vol 2 (3) ◽  
pp. 120-122 ◽  
Author(s):  
Stanley W Epstein ◽  
Tetsuo Inouye ◽  
Michael Robson ◽  
Dimitrios G Oreopoulos
Keyword(s):  
Peritoneal Dialysis ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Abdominal Cavity ◽  
Dry Weight ◽  
The Body ◽  
Lung Volumes ◽  
Significant Difference ◽  
Peritoneal Dialysis Fluid ◽  
Residual Capacity ◽  
Helium Dilution

Lung function was measured in eight patients undergoing continuous ambulatory peritoneal dialysis using two litres of dialysate fluid and in one patient using three litres of fluid. With the patient sitting, lung volumes were measured by body plethysmographic and helium dilution techniques and a forced vital capacity, before and after removal of dialysate fluid from the abdominal cavity. The patients selected were free of lung disease and were at stable dry weight. No significant difference was found in maximum expiratory flow rates or lung volumes measured by the body plethysmography after removal of the fluid. However, the helium dilution technique showed changes in lung volumes; here the functional residual capacity was increased by 590 ml (SE 209 ml, p < 0.05) in the eight patients using two litres of fluid. Others have reported similar findings in patients on continuous ambulatory peritoneal dialysis. The findings suggest that the introduction of fluid into the peritoneal cavity has no detrimental effect on diaphragmatic configuration and function.

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