Sa1232 Validation of a Novel Clinical Prediction Scale for Hospital-Onset Clostridium difficile Infection Confirmed Using Polymerase Chain Reaction Assay

2013 ◽  
Vol 144 (5) ◽  
pp. S-237
Author(s):  
Subhash Chandra ◽  
Erez A. Minka ◽  
Rameet Thapa ◽  
Margarita Noel ◽  
Surendra Marur ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Polymerase Chain Reaction Assay ◽  
Clinical Prediction ◽  
Chain Reaction ◽  
Polymerase Chain

An Evaluation of Repeat Stool Testing for Clostridium difficile Infection by Polymerase Chain Reaction

2012 ◽  
Vol 46 (10) ◽  
pp. 846-849 ◽  
Author(s):  
Sahil Khanna ◽  
Darrell S. Pardi ◽  
Jon E. Rosenblatt ◽  
Robin Patel ◽  
Patricia P. Kammer ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Chain Reaction ◽  
Polymerase Chain

Detection of Clostridium difficile Infection

2010 ◽  
Vol 31 (S1) ◽  
pp. S35-S37 ◽  
Author(s):  
John G. Bartlett
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Diagnostic Tests ◽  
Clinical Laboratory ◽  
Rapid Diagnostic Tests ◽  
Testing Methods ◽  
Chain Reaction ◽  
Immune Mechanisms ◽  
Polymerase Chain

There has been a recent surge of interest in Clostridium difficile infection, which reflects an impressive increase in the number and severity of these infections. This review addresses some of the newer methods for detection of C. difficile infection at the bedside and in the laboratory. Particularly important are the new rapid diagnostic tests that detect toxigenic C. difficile using polymerase chain reaction and the combination tests that, either simultaneously or sequentially, screen for C. difficile and test for toxins A and B. It is expected that these new testing methods will largely supplant the enzyme immunoassays for toxins, which are used by most laboratories, departments, and divisions. The present goal is to combine clinical, laboratory, and animal research related to C. difficile that reflects issues that are considered to be major contemporary challenges. Among this work is the pursuit of studies of immune mechanisms to better control this disease.

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