O481 Gestational age-specific reference intervals for 32 chemical, 13 hematological, 10 coagulation and 3 thyroid laboratory tests during 391 uncomplicated pregnancy, vaginal delivery and early postpartum period

2009 ◽  
Vol 107 ◽  
pp. S230-S230
Author(s):  
A. Klajnbard ◽  
N. Palmgren Colov ◽  
P. Szecsi ◽  
M. Jørgensen ◽  
M. Rohr Andersen ◽  
...  
Keyword(s):  
Vaginal Delivery ◽  
Gestational Age ◽  
Postpartum Period ◽  
Laboratory Tests ◽  
Reference Intervals ◽  
Specific Reference ◽  
Early Postpartum Period ◽  
Uncomplicated Pregnancy ◽  
Early Postpartum

The value of vaginal lactobacilli in the restoration of vaginal microbiocenosis in women in the early postpartum period, depending on the method of delivery

2021 ◽  
Vol 70 (4) ◽  
pp. 15-23
Author(s):  
Dzhamilya G. Dadayeva ◽  
Olga V. Budilovskaya ◽  
Anna A. Krysanova ◽  
Tatyana A. Khusnutdinova ◽  
Alevtina M. Savicheva ◽  
...  
Keyword(s):  
Vaginal Delivery ◽  
Postpartum Period ◽  
Vaginal Discharge ◽  
Vaginal Microbiota ◽  
Clinical Material ◽  
Birth Canal ◽  
Early Postpartum Period ◽  
Vaginal Microflora ◽  
Early Postpartum ◽  
Before And After

BACKGROUND: Despite numerous studies of the vaginal microbiota, there is still a lack of knowledge regarding its restoring dynamics in the early postpartum period. The condition of the vaginal microflora during pregnancy plays a key role in maintaining the physiological microbiocenosis of the birth canal and creating conditions for the normal course of pregnancy, the establishment of an infants intestinal microbiota, and the further development of the child. AIM: The aim of this study was to estimate the role of certain types of lactobacilli in restoring the vaginal microbiota in women in the early postpartum period, depending on the method of delivery. MATERIALS AND METHODS: We examined 150 women at 38-41 weeks of gestation. The clinical material for the study was vaginal discharge before and after delivery. To determine the species of lactobacilli and other microorganisms in the clinical material, we used quantitative real-time PCR. RESULTS: Before delivery, lactobacilli were found in vaginal discharge in 144 out of 150 women (96.0%), their number in the majority being more than 106 GE. In the postpartum period, lactobacilli were found in 66/128 (51.5%) cases, while prevailing in women after vaginal delivery in 50/65 (76.9%) cases (4.61.6, p = 0.000000). Among the dominant species of lactobacilli was L. crispatus, found in vaginal discharge before delivery, which most often affects the recovery of the vaginal microbiota in the postpartum period (29 out of 61 women, 47.5%). L. iners detected in the lochia predisposes to the violation of uterine involution in the early postpartum period (p = 0.03). CONCLUSIONS: Normal vaginal microbiota in the postpartum period is restored more quickly in women after vaginal delivery. Our study confirms that L. crispatus and L. iners play a major role in restoring the vaginal microbiota in the postpartum period.

Reference ranges of rotational thromboelastometry parameters in pregnant women and puerperas: a single-center randomized trial

2020 ◽  
Author(s):  
Ю.С. Распопин ◽  
В.В. Потылицина ◽  
А.И. Грицан ◽  
А.В. Ковалев ◽  
И.А. Ольховский
Keyword(s):  
Pregnant Women ◽  
Postpartum Period ◽  
Reference Intervals ◽  
Reference Ranges ◽  
Rotational Thromboelastometry ◽  
Early Postpartum Period ◽  
Krasnoyarsk Region ◽  
Early Postpartum ◽  
Coagulation Tests ◽  
Obstetric Surgery

Введение: В последнее время стали востребованы интегральные тесты оценки системы гемостаза у женщин во время беременности, а также во время акушерских операций, связанных с кровотечением. В нашей стране отсутствуют работы по определению популяционных норм ротационной тромбоэластометрии (РОТЕМ) у беременных, рожениц и родильниц. Цель исследования: определить пределы референсных интервалов показателей РОТЕМ во время физиологически протекающей беременности и в раннем послеродовом периоде и провести корреляционный анализ со стандартными показателями коагулограммы. Материалы и методы: Обследовано 229 женщин Красноярского края, которые были поделены на 5 групп: небеременные (контроль), беременные II и III триместров, женщины раннего послеродового периода после операции кесарева сечения и естественных родов. Все женщины были сопоставимы по возрасту, индексу массы тела, сопутствующей патологии. Референсные интервалы рассчитывали либо через среднее и стандартное отклонение (для нормального распределения), либо через медиану и 2,5 и 97,5% перцентили (для ненормального распределения). Результаты: В процессе исследования подтвердилось, что во время беременности и в раннем послеродовом периоде происходят изменения в системе гемостаза в сторону гиперкоагуляции. Показатели ROTЕM у женщин в III триместре беременности и раннем послеродовом периоде существенно отличаются от показателей небеременных в популяции. У женщин после родов вне зависимости от способа родоразрешения различий между параметрами ROTЕM не установлено. Корреляция между параметрами ROTЕM и традиционными лабораторными тестами коагуляции выявила взаимосвязь между амплитудой плотности сгустка в тесте FIBTEM и уровнем фибриногена по Клаусу. Заключение: Представлены референсные интервалы параметров РОТЕМ у женщин Красноярского края. Найдена корреляция между параметрами РОТЭМ и уровнем фибриногена. Background: Recently, integral tests for hemostasis assessment in pregnant women as well as during obstetric surgery associated with bleeding have become popular. In our country, there are no studies of population norms for rotational thromboelastometry (ROTEM) in pregnant women, parturients and puerperants. Objectives: to identify reference intervals limits for ROTEM parameters during physiological pregnancy and in early postpartum period and to carry out correlation analysis with standard coagulogram parameters. Patients/Methods: We examined 229 women in Krasnoyarsk region; they were divided into 5 groups: nonpregnant (control), pregnant women in II and III trimesters, women in early postpartum period after cesarean section and after vaginal delivery. All women were comparable in age, body mass index, and concomitant pathology. Reference intervals were calculated either as the mean and standard deviation (for normal distribution), or as the median and 2.5 and 97.5% percentiles (for abnormal distribution). Results: The study confirmed hemostasis hypercoagulation changes during pregnancy and in early postpartum period. ROTEM parameters in women in III trimester of pregnancy and in early postpartum period differ significantly from those in non-pregnant women. Differences between ROTEM parameters in puerperants, regardless of the delivery method, not found. The correlation between ROTEM parameters and traditional laboratory coagulation tests revealed a relationship between clot density amplitude in FIBTEM test and Klaus fi brinogen level. Conclusions: Reference intervals of ROTEM parameters in women of Krasnoyarsk region are presented. A correlation was found between ROTEM parameters and fibrinogen level

scholarly journals Laboratory reference intervals during pregnancy, delivery and the early postpartum period

2010 ◽  
Vol 48 (2) ◽  
Author(s):  
Anna Klajnbard ◽  
Pal B. Szecsi ◽  
Nina P. Colov ◽  
Malene R. Andersen ◽  
Maja Jørgensen ◽  
...  
Keyword(s):  
Postpartum Period ◽  
Reference Intervals ◽  
Early Postpartum Period ◽  
Early Postpartum ◽  
Laboratory Reference

scholarly journals The lactation process in primiparas in early postpartum period depending on the mode of delivery. The mode of delivery and the lactation process

2017 ◽  
Vol 16 (3) ◽  
pp. 34-41
Author(s):  
Magdalena Humaj-Grysztar ◽  
Monika Bobek ◽  
Dorota Matuszyk ◽  
Marzena Put
Keyword(s):  
Cesarean Section ◽  
Cesarean Delivery ◽  
Vaginal Delivery ◽  
Postpartum Period ◽  
Mode Of Delivery ◽  
Research Tool ◽  
Early Postpartum Period ◽  
Early Postpartum ◽  
Almost All ◽  
The Relationship

Abstract Aim. The aim of the study was to determine the relationship between the mode of delivery and the course of lactation in primiparas in early postpartum period. Material and methods. The research was conducted amongst 200 primiparas including 100 after vaginal delivery and 100 after cesarean section. The study was conducted with the method of diagnostic survey with the author’s original questionnaire as a research tool. Results. The women after vaginal delivery initiate breastfeeding earlier and more often find it successful (p < 0.001). Almost all the primiparas after cesarean delivery formula-fed their newborns (p < 0.001) and they started supplementary formula feeding earlier in comparison to women who had vaginal delivery (p < 0.001). Problem-free breastfeeding was declared by 15% of the respondents after vaginal delivery and 4% of those who had a cesarean section. Conclusions. The mode of delivery influences the lactation process. The primiparas after cesarean delivery had problems with breastfeeding more often than those after vaginal birth.

scholarly journals Exclusive Breastfeeding Is Not Associated with Maternal–Infant Bonding in Early Postpartum, Considering Depression, Anxiety, and Parity

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1184
Author(s):  
Naoki Fukui ◽  
Takaharu Motegi ◽  
Yuichiro Watanabe ◽  
Koyo Hashijiri ◽  
Ryusuke Tsuboya ◽  
...  
Keyword(s):  
Mental Health ◽  
Path Analysis ◽  
Exclusive Breastfeeding ◽  
Postpartum Period ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Women’S Mental Health ◽  
Women's Mental Health ◽  
Early Postpartum Period ◽  
Early Postpartum

It is important to clarify how the breastfeeding method affects women’s mental health, and how women’s mental health affects the breastfeeding method in the early postpartum period when major depression and other psychiatric problems are most likely to occur. This study aimed to examine this bidirectional relationship in the early postpartum period. Participants were 2020 postpartum women who completed the Hospital Anxiety and Depression Scale (HADS) and Mother-to-Infant Bonding Scale (MIBS). We obtained data for participants’ breastfeeding method for four weeks after childbirth. We performed a path analysis with factors including breastfeeding method (exclusive breastfeeding or non-exclusive breastfeeding), parity (primipara or multipara), the two HADS subscales (anxiety and depression), and the two MIBS subscales (lack of affection and anger and rejection). The path analysis showed that breastfeeding method did not significantly affect depression, anxiety, and maternal–infant bonding in the early postpartum period. Women with higher anxiety tended to use both formula-feeding and breastfeeding. Our study suggests that exclusive breastfeeding is not associated with maternal-fetal bonding in early postpartum, considering depression, anxiety, and parity.

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