AGE-RELATED DECLINE OF ANDROGENS IN A CROSS- SECTIONAL STUDY

ObjectiveTo explore the association between age-related macular degeneration (AMD) and arthritis in a representative sample of the US population.DesignPopulation-based, cross-sectional study.SettingThe National Health and Nutrition Examination Survey (NHANES) 2005–2008.ParticipantsA total of 4813 participants aged 40 years and older with available information on AMD and arthritis in the 2005–2008 NHANES.MethodsThe status and types of arthritis were obtained from questionnaires. Non-mydriatic fundus photographs were collected. The types of AMD were assessed using the modified Wisconsin Age-Related Maculopathy Grading Classification Scheme. The association between arthritis and AMD was evaluated using logistic regression models.ResultsAfter adjusting for covariates, participants with any or early AMD had significantly lower odds of having any type of arthritis (any AMD: OR=0.56, 95% CI: 0.36–0.86; early AMD: OR=0.55, 95% CI: 0.34–0.88) or osteoarthritis (OA) (any AMD: OR=0.43, 95% CI: 0.26–0.71; early AMD: OR=0.44, 95% CI: 0.25–0.76) compared with those without AMD. When considering AMD as the outcome, significant negative associations were also found between any arthritis or OA and any (any arthritis: OR=0.64, 95% CI: 0.43–0.94; OA: OR=0.52, 95% CI: 0.33–0.82) or early AMD (any arthritis: OR=0.61, 95% CI: 0.40–0.93; OA: OR=0.51, 95% CI: 0.31–0.86) in the multivariable logistic models. There was no significant association between different types of arthritis and late AMD.ConclusionsPeople with arthritis, especially those with OA, were less likely to have AMD compared with those without arthritis and vice versa. Further studies are needed to confirm this potential protective effect of arthritis and/or arthritis treatment on AMD and to explore the underlying mechanisms.

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Factors associated with physical, psychological and social frailty among community-dwelling older persons in Europe: a cross-sectional study of Urban Health Centres Europe (UHCE)

BMC Geriatrics ◽

10.1186/s12877-021-02364-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Lizhen Ye ◽

Liset E. M. Elstgeest ◽

Xuxi Zhang ◽

Tamara Alhambra-Borrás ◽

Siok Swan Tan ◽

...

Keyword(s):

Risk Factors ◽

Urban Health ◽

Cross Sectional Study ◽

Community Dwelling ◽

Household Composition ◽

European Countries ◽

Sectional Study ◽

Related Condition ◽

Cross Sectional ◽

Age Related

Abstract Background Frailty is an age-related condition resulting in a state of increased vulnerability regarding functioning across multiple systems. It is a multidimensional concept referring to physical, psychological and social domains. The purpose of this study is to identify factors (demographic characteristics, lifestyle factors and health indicators) associated with overall frailty and physical, psychological and social frailty in community-dwelling older people from five European countries. Methods This cross-sectional study used baseline data from 2289 participants of the Urban Health Center European project in five European countries. Multivariable logistic regression models were used to assess associations of the factors with overall frailty and the three frailty domains. Results The mean age was 79.7 (SD = 5.7). Participants who were older, were female, had secondary or equivalent education, lived alone, not at risk of alcohol use, were less physically active, had multi-morbidity, were malnourished or with a higher level of medication risk, had higher odds of overall frailty (all P < 0.05). Age was not associated with psychological and social frailty; sex was not associated with social frailty; smoking and migration background was not associated with overall frailty or any of its domains. There existed an interaction effect between sex and household composition regarding social frailty (P < 0.0003). Conclusions The present study contributed new insights into the risk factors for frailty and its three domains (physical, psychological and social frailty). Nurses, physicians, public health professionals and policymakers should be aware of the risk factors of each type of frailty. Furthermore, examine these risk factors more comprehensively and consider overall frailty as well as its three domains in order to further contribute to decision-making more precisely on the prevention and management of frailty. Trial registration The intervention of the UHCE project was registered in the ISRCTN registry as ISRCTN52788952. The date of registration is 13/03/2017.

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The determinants of performance in master swimmers: a cross-sectional study on the age-related changes in propelling efficiency, hydrodynamic position and energy cost of front crawl

European Journal of Applied Physiology ◽

10.1007/s00421-012-2376-y ◽

2012 ◽

Vol 112 (12) ◽

pp. 3949-3957 ◽

Cited By ~ 12

Author(s):

P. Zamparo ◽

A. Dall’Ora ◽

A. Toneatto ◽

M. Cortesi ◽

G. Gatta

Keyword(s):

Energy Cost ◽

Cross Sectional Study ◽

Sectional Study ◽

Front Crawl ◽

Cross Sectional ◽

Age Related ◽

Propelling Efficiency ◽

Age Related Changes

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Factors responsible for age-related elevation in fasting plasma glucose: a cross-sectional study in Japanese men

Metabolism ◽

10.1016/j.metabol.2007.10.002 ◽

2008 ◽

Vol 57 (2) ◽

pp. 299-303 ◽

Cited By ~ 7

Author(s):

Kentaro Toyoda ◽

Mitsuo Fukushima ◽

Rie Mitsui ◽

Norio Harada ◽

Hidehiko Suzuki ◽

...

Keyword(s):

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Japanese Men ◽

Fasting Plasma ◽

Age Related

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Age-related variation in mobility independence among wheelchair users with spinal cord injury: A cross-sectional study

Journal of Spinal Cord Medicine ◽

10.1179/2045772315y.0000000008 ◽

2016 ◽

Vol 39 (2) ◽

pp. 180-189 ◽

Cited By ~ 4

Author(s):

Timo Hinrichs ◽

Veronika Lay ◽

Ursina Arnet ◽

Inge Eriks-Hoogland ◽

Hans Georg Koch ◽

...

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Wheelchair Users ◽

Related Variation ◽

Age Related ◽

Cord Injury

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Age threshold for recommending higher protein intake to prevent age-related muscle weakness: A cross-sectional study in Japan

PLoS ONE ◽

10.1371/journal.pone.0208169 ◽

2018 ◽

Vol 13 (12) ◽

pp. e0208169 ◽

Cited By ~ 1

Author(s):

Hitomi Suga ◽

Hideki Hashimoto

Keyword(s):

Muscle Weakness ◽

Protein Intake ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Age Related

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Associations of n-3 Fatty Acids and Fish Consumption with the Metabolic Syndrome in College Students (P18-022-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz039.p18-022-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Nicole Karazurna ◽

Caitlin Porter ◽

Jesse Stabile Morrell ◽

Sherman Bigornia

Keyword(s):

Risk Factors ◽

College Students ◽

Metabolic Syndrome ◽

Young Adults ◽

Fish Consumption ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

The Metabolic Syndrome ◽

Age Related

Abstract Objectives Evidence suggests that omega-3 fatty acid (n-3 FA) and fish consumption may reduce the risk of the metabolic syndrome (MetS) in older adults. We previously reported that MetS components are prevalent among college students. Identifying modifiable risk factors of developing MetS and its components in young adults will inform potential targets to reduce the risk of age-related health conditions. Our objectives were to measure the cross-sectional impacts of n-3 FA and fish consumption on ≥2 or ≥3 MetS criteria and individual criteria among college students. Methods The College Health and Nutrition Assessment Survey is an on-going cross-sectional study at a public New England college. We examined data from Jan 2008 – May 2017. After excluding those with missing data our final sample size was n = 4271 for n-3 FA & n = 2072 for fish intake analyses. Diet was assessed by a 3 day food record; MetS criteria were collected in fasted state. We expressed n-3 FAs as g/1000 kcals/d. Servings of fish/week was obtained via an online survey. Individuals were categorized as consuming ≥ 2 servings/week or not. MetS was defined as meeting ≥ 3 criteria: elevated glucose, triglycerides, blood pressure, waist circumference, and low HDL. Analyses were conducted by logistic regression. Results The average n-3 FA intake was 0.4 g/1000 kcal/d ± 0.25 & 40% consumed ≥ 2 servings of fish/week. Prevalence estimates for meeting ≥ 2 criteria was 18.8% and 4.8% for MetS. In sex- and energy- adjusted models, n-3 FA consumption was inversely associated with MetS (OR = 0.38; 95%CI: 0.20, 0.71) and ≥2 MetS criteria (OR = 0.67; 95%CI: 0.49, 0.91). Associations were no longer significant after considering additional confounders. Fish consumption was not significantly associated with MetS or ≥2 criteria in any model. Further n-3 FAs and fish consumption was not associated with any individual MetS criteria. Conclusions In this cross-sectional study among college students, n-3 FA and fish consumption were not significantly associated with MetS outcomes. Further research is needed in this population using longitudinal study designs to understand long-term impact of n-3 consumption on the development of MetS and associated cardio metabolic risk factors in young adults. Funding Sources New Hampshire Agriculture Experiment Station and USDA National Institute of Food and Agriculture Hatch Project 1010738.

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Variability of the Aging Process in Dementia-Free Adults With Down Syndrome

American Journal on Intellectual and Developmental Disabilities ◽

10.1352/1944-7558-120.1.3 ◽

2015 ◽

Vol 120 (1) ◽

pp. 3-15 ◽

Cited By ~ 10

Author(s):

Raphaele Tsao ◽

Cecile Kindelberger ◽

Benedicte Fréminville ◽

Renaud Touraine ◽

Gerald Bussy

Keyword(s):

Down Syndrome ◽

Cognitive Functioning ◽

Aging Process ◽

Interindividual Variability ◽

Cross Sectional Study ◽

Social Adaptation ◽

Sectional Study ◽

Cross Sectional ◽

Age Related ◽

Psychopathological Disorders

Abstract The aim of this cross-sectional study was to analyze the typical aging process in adults with Down syndrome, focusing on its variability. The sample comprised 120 adults with Down syndrome who were free of dementia. Ages ranged from 20 to 69 years. Each participant was assessed on cognitive functioning and social adaptation, and was checked for the presence of psychopathological disorders. Results revealed an age-related deterioration in both cognitive and social adaptation skills, the extent of this decline depending on the dimension under scrutiny, and interindividual variability in aging profiles.

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