Just the Facts: Management of cyclopeptide mushroom ingestion

CJEM ◽  
2020 ◽  
Vol 22 (5) ◽  
pp. 644-647
Author(s):  
Nicholas J. Connors ◽  
Robert S. Hoffman ◽  
Sophie Gosselin

A 54-year-old woman prepares dinner around 8:00 pm that includes mushrooms that she picked from her yard. The next morning, around 8:00 am, the woman (patient), her daughter, and son-in-law all develop abdominal cramps, violent vomiting, and diarrhea. They present to the emergency department and are admitted for dehydration and intractable vomiting with a presumed diagnosis of food poisoning. Twenty-four hours later, they appear well with stable vital signs and improved symptoms. Four hours later, 36 hours post-ingestion, the patient becomes lethargic. A venous blood gas reveals pH, 7.1; PCO2, 16 mmHg; and her AST was 3140 units/L with an ALT of 4260 units/L and an INR of 3.7.

2011 ◽  
Vol 18 (10) ◽  
pp. 1105-1108 ◽  
Author(s):  
Michael Menchine ◽  
Marc A. Probst ◽  
Chad Agy ◽  
Dianne Bach ◽  
Sanjay Arora

2017 ◽  
Vol 12 (5) ◽  
pp. 1849-1857 ◽  
Author(s):  
Lisa Domaradzki ◽  
Sahithi Gosala ◽  
Khaled Iskandarani ◽  
Andry Van de Louw

2013 ◽  
Vol 3 (2) ◽  
pp. 29-33
Author(s):  
Ertan Bakoğlu ◽  
Ali Sedat Kebapçıoğlu ◽  
Ahmet Ak ◽  
Abdullah Sadık Girişgin ◽  
İsmail Zararsız

2021 ◽  
Vol 20 (3) ◽  
pp. 178-182
Author(s):  
Ram Kirubakar Thangaraj ◽  
Hari Hara Sudhan Chidambaram ◽  
Melvin Dominic ◽  
V.P. Chandrasekaran ◽  
Karthik Narayan Padmanabhan ◽  
...  

CJEM ◽  
2019 ◽  
Vol 22 (1) ◽  
pp. 19-22
Author(s):  
Justin W. Yan ◽  
Tamara Spaic ◽  
Selina Liu

A 21-year-old male with known type 1 diabetes mellitus presented to the emergency department (ED) with two days of vomiting, polyuria, and polydipsia after several days of viral upper respiratory tract infection symptoms. Since his symptom onset, his home capillary blood glucose readings have been higher than usual. On the day of presentation, his glucometer read “high,” and he could not tolerate oral fluids. On examination, his pulse was 110 beats/minute, and his respiratory rate was 24 breaths/minute. He was afebrile, and the remaining vital signs were normal. Other than dry mucous membranes, his cardiopulmonary, abdominal, and neurologic exams were unremarkable. Venous blood gas demonstrated a pH of 7.25 mm Hg, pCO2 of 31 mm Hg, HCO3 of 13 mm Hg, anion gap of 18 mmol/L, and laboratory blood glucose of 40 mmol/L, as well as serum ketones measuring “large.”


Author(s):  
Kathryn Boyle ◽  
Ben McNaughten ◽  
Andrew Thompson ◽  
Stephen Mullen

Case summaryA 10-year-old boy presented with severe progressive generalised weakness on a background of 3 days of diarrhoea and vomiting. Vital signs were normal. Peripheral neurological examination revealed grade 1–2 power in all limbs, hypotonia and hyporeflexia. Sensation was fully intact. Cranial nerve examination and speech were normal. The ECG (figure 1) and initial venous blood gas (figure 2) are shown.Figure 1ECG.Figure 2Venous blood gas.Question 1What abnormalities are present on the ECG?Peaked T waves, prolonged PR segment and loss of P waves?Shortening of the QT interval and Osborn waves (J waves)?T wave flattening/inversion, prominent U waves and long QU interval?Prolonged QT interval with multiple atrial and ventricular ectopics?Question 2How would you manage this patient’s hypokalaemia?Question 3What is the likely diagnosis?Conversion disorder.Myasthenia gravis.Periodic paralysis.Guillain-Barré syndrome.Botulism.Question 4What interventions can be considered for long-term treatment of this condition?Answers can be found on page 2.


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