Serum pyridoxine, folate, cobalamin, and homocysteine levels in children presenting with vasovagal syncope

2021 ◽  
pp. 1-7
Author(s):  
Tetiana Kovalchuk ◽  
Oksana Boyarchuk
Keyword(s):  
Blood Pressure Monitoring ◽  
Vasovagal Syncope ◽  
Holter Monitoring ◽  
Qtc Interval ◽  
Healthy Children ◽  
New Approach ◽  
Immunoassay Technique ◽  
History Of ◽  
Sandwich Enzyme Immunoassay

Abstract Background: Recent studies confirm the role of B vitamins deficiency and hyperhomocysteinaemia in the development of dysautonomia that has been considered to be the main factor in vasovagal syncope development. The aim of the study was to investigate serum pyridoxine, folate, cobalamin, and homocysteine levels in children presenting with vasovagal syncope and to analyse the correlation between them and main clinical parameters of syncope. Methods: We studied 40 children, ages 8–17 years with a history of vasovagal syncope and 24 healthy volunteers. The serum pyridoxine, folate, cobalamin, and homocysteine levels were measured by a quantitative sandwich enzyme immunoassay technique using a commercial kit (Monobind, USA). Twenty-four-hour Holter monitoring and 24-hour ambulatory blood pressure monitoring were conducted for all participated patients. Results: Serum pyridoxine (9.42 ± 4.87, 16.11 ± 5.53 µg/L) and cobalamin (307.48 ± 95.50, 447.28 ± 108.85 ng/L) levels were reasonably low (p < 0.05) in patients with vasovagal syncope. Although there was no significant change in folate levels between syncope and healthy children (4.00 ± 1.34, 4.71 ± 1.73 µg/L; p = 0.20), we detected low folate-level association with longer duration of syncope (r = −0.42) and post syncope (r = −0.43) symptoms (p < 0.05). Finally, there was increased serum homocysteine level (13.55 ± 5.03, 7.81 ± 1.71 µmol/L; p < 0.05) in patients with vasovagal syncope. It was positively correlated with the average PQ interval (r = 0.35, p < 0.05) and average QTc interval (r = 0.49, p < 0.05). Conclusions: The results suggested that pyridoxine, folate, cobalamin, and homocysteine may be involved in the pathogenesis of vasovagal syncope. This might provide a new approach for effective treatment of paediatric vasovagal syncope, requiring further study.

scholarly journals The Adventures of Feldkurat Karl Drexel in Siberia (According to Archival Sources). Part 2

2020 ◽  
Vol 34 ◽  
pp. 6-12
Author(s):  
А. V. Anufriev ◽  
◽  
D. V. Kozlov ◽  
Keyword(s):  
Prisoners Of War ◽  
Red Cross ◽  
Joint Operation ◽  
General Staff ◽  
Historical Sources ◽  
New Approach ◽  
Internal Logic ◽  
History Of ◽  
The Coordinator

We can analyze the fate of one of these priests – the ober- feldkurat of the Austro – Hungarian army Karl Drexel. To describe his activities, the article uses a variety of new archival sources, as well as the diary of a priest. During the Russian offensive operation, the priest was taken prisoner in the battle of RabbaRusskaya. In 1915 K. Drexel came under the operational supervision of the Intelligence Department of the Amur military district. He was suspected of creating a secret organization of officers of the Austro-Hungarian army to escape and espionage. At the same time, the gendarmerie also monitored him. K. Drexel falls under the operational supervision of two serious departments at once: the Intelligence Department of the headquarters of the Irkutsk military district and the Irkutsk provincial gendarmerie Department. During the joint operation, the role of K. Drexel as the organizer of the escapes of prisoners of war and the coordinator of illegal assistance to prisoners, both through the Red Cross and the diplomatic mission in China, was revealed. According to the results of the investigation, appropriate decisions were made. Drexel was arrested and his diary was seized. It contains a synopsis of memories. According to the decision of the Main Directorate of the General staff of 1916, September 21 K. Drexel was sent to the Amur military district and was escorted to Khabarovsk on September 26. It should be emphasized that the historical sources analyzed in the article, help to develop a new approach to the analysis of such an interesting topic as the transformation of the manifestations of loyalty and patriotism of PoW. In this case, it is possible to analyze such manifestations both in relation to the homeland and in relation to the country of captivity. The article is divided into two parts based on the internal logic of the presentation of the material. The second part of the article examines Drexel's stay in the PoW camps in Eastern Siberia, the history of his arrest and investigation of his “espionage” activities, and his subsequent fate.

scholarly journals David Lewis-Williams’s Cognitive Archeology: New Approach to Shamanism

2019 ◽  
pp. 92-97
Author(s):  
Aleksandra D. Belova ◽  
Keyword(s):  
Social Organization ◽  
David Lewis ◽  
Large Role ◽  
New Approach ◽  
History Of Religions ◽  
History Of ◽  
Rock Paintings ◽  
Definition Of ◽  
Main Ideas

The article outlines the main ideas of the archaeologist David Lewis-Williams and his contribution to the study of shamanism and the analysis of rock paintings. Author examines the depicted scenes, the process of the painting, as well as artifacts and ethnographic evidences of the alleged rituals. The reconstruction of rituals is accompanied by the Lewis-Williams’s conception of the spectrum of consciousness and its various states. Universal mental images arising during ASCs played a large role in the genesis of shamanism, and their fixation in rock art allows one to reconstruct the inner state of the creators of images and the role of trance experiences. The author finds confirmation of his concept in the history of religions. The article also contains critical remarks on the Lewis-Williams’ theory, mainly related to the definition of symbolic activity and the insufficient attention of the author to social organization. The author of the article partially agrees with the criticism, and also brings auxiliary theories that remove some of the criticism. The article outlines the prospects for using the Lewis-Williams’ method in analyzing not only rock paintings, but also folklore sources.

A New Approach to Islamic Intellectual Tradition

2020 ◽  
Author(s):  
Ali Unsal
Keyword(s):  
Sixteenth Century ◽  
The State ◽  
Muslim World ◽  
Intellectual Tradition ◽  
New Approach ◽  
History Of ◽  
Muslim Intellectuals ◽  
Islamic Civilization ◽  
Muslim Scholars

This article attempts to explain the state of contemporary Islamic Intellectualism. Additionally, it proposes a set of abilities, attributes, and responsibilities that Muslim scholars should possess to develop Islamic Intellectualism. To achieve this, this article first provides an analysis of the history of Islamic civilization, and the role of traditional Islamic Intellectualism in pushing the civilization towards new heights in the realms of societal organization, politics, culture, economics, and theology. Islam, as such, had experienced its first renaissance from the eighth to the sixteenth century. Today, the Muslim world is in need of a second renaissance. This is the context in which this article situates the ‘standards’ to which contemporary Muslim intellectuals must strive towards.

Euro-Gott im starken Plural? Einige Fragestellungen für eine europäische Religionsgeschichte des 20. Jahrhunderts

2005 ◽  
Vol 3 (2) ◽  
pp. 231-257 ◽  
Author(s):  
Friedrich Wilhelm Graf
Keyword(s):  
20Th Century ◽  
Modern World ◽  
Religious Institutions ◽  
Great Flexibility ◽  
New Approach ◽  
History Of Religion ◽  
German Speaking ◽  
History Of ◽  
European Development

Euro-God as a Beneficent Plurality? Some approaches for a history of European religion in the 20th century Since the 1980s, general historians in the German-speaking parts of Europe have begun intensively to research the history of religion in the contemporary era. Earlier concepts such as «dechristianisation» and «secularisation» have been replaced by a new receptiveness for the formative influence of the manifold interpretations of the world and the search for life's meaning in this modern world. Astonishingly enough, this new approach to the history of religion has not led to debates about methodology. Approaches have been developed leading to a better understanding of the transformation in religion as it is affected by the specific modernity of 20th century Europe. How can historians describe the great flexibility of the symbolic languages of religion and the interplay of adaptability and formative power of religious institutions? Is there a specific pan-European development of deinstitutionalisation of religion? What role do the history of theological ideas and the theological disciplines in the history of 20th century religion play? How may the role of the Churches as the traditionally most important religious megainstitutions in European society be described? Which analytical means promise especially enlightening insights?

scholarly journals Determing the Role of Debt in the Economy and a New Approach for Solving Sovereign Debt Crises

2013 ◽  
Author(s):  
Munawar Iqbal
Keyword(s):  
Sovereign Debt ◽  
Global Financial Crisis ◽  
Debt Crisis ◽  
Policy Makers ◽  
New Approach ◽  
The Past ◽  
History Of ◽  
Debt Crises

This paper aims to begin a dialogue on how to seek a longer term solution to the sovereign debt problems in general and those of EU in particular. Although the history of debt crises is quite old, none of the several solutions proposed and tried in the past have been successful to curb recurring debt crisis. This issue has assumed critical importance as the Eurozone debt crisis, which followed after the 2007-09 global financial crisis. Several governments have been outvoted in Europe due to this crisis and the cohesion of Eurozone is at stake. A rethinking on debt creation and its macroeconomic effects are being seriously studied. It seems that traditional options available to policy makers have lost much of their luster. It is high time that unconventional measures may have to be offered for consideration to provide longer term solution. This paper is a brief on the Islamic approach to the role of debt, and has potential to limit debt creation in the long term. We present some basic tenets of that approach referring in particular to the current developed nation sovereign debt crisis.  

Long QT Syndrome: A Case Report, Genomics, and Clinical Implications

2010 ◽  
Vol 3 (1) ◽  
pp. 31-35
Author(s):  
Jiaming Yao ◽  
Kathleen Hickey
Keyword(s):  
Long Qt Syndrome ◽  
Clinical Manifestations ◽  
Clinical History ◽  
Clinical Implications ◽  
Qtc Interval ◽  
Long Qt ◽  
Genetic Syndrome ◽  
History Of ◽  
Qt Syndrome

Long QT syndrome (LQTS) is a hereditary disorder in which the majority of affected individuals present with QT prolongation on electrocardiograms (ECGs), arising from delayed ventricular repolarization. This commonly arrhythmia-associated genetic syndrome can lead to sudden cardiac death (SCD) and increased propensity for arrythmogenic syncope. The authors describe the case of a young patient who presented with episodes of syncope, prolonged QTc interval on ECG, and family history of SCD. He subsequently received an ICD for protection against SCD based on his prior clinical history. The article discusses the clinical manifestations, electrocardiographic (ECG) findings, management of LQTS, and role of the clinician in testing, teaching, and counseling the affected patients and families.

scholarly journals Socialist Republican Discourse and the 1916 Easter Rising: The Occupation of Jacob's Biscuit Factory and the South Dublin Union Explained

2014 ◽  
Vol 53 (4) ◽  
pp. 992-1010 ◽  
Author(s):  
Lauren Arrington
Keyword(s):  
The South ◽  
Urban Context ◽  
Popular Discourse ◽  
New Approach ◽  
Easter Rising ◽  
Political Sovereignty ◽  
History Of ◽  
Political Value ◽  
The Way

AbstractThe events of the Easter Rising have been subjected to extensive analysis by historians who have focused on military strategy as a means of explaining the occupation of specific sites. However, Jacob's Biscuit Factory and the South Dublin Union have proven resistant to this paradigm. The political value of both places can be understood by giving close attention to the long history of antagonism between these two institutions and the Irish Transport and General Workers' Union, out of which the Irish Citizen Army that fought in the rising was formed. In his articles for the Irish Worker and Workers' Republic, James Connolly adapted traditional republican discourse of economic emancipation through political sovereignty to address a contemporary urban context. An understanding of the way that this discourse functioned facilitates an understanding of the role of Jacob's Biscuit Factory and the South Dublin Union in the Easter Rising: as sites of actual and symbolic liberation. This analysis of popular discourse in the contemporary press offers a new approach to the study of events that have been termed the Irish Revolution, and it presents a model for understanding the way that republican discourse accommodated the very different political objectives of Irish separatists.

Elaborating the role of reflection and individual differences in the study of folk-economic beliefs

2018 ◽  
Vol 41 ◽  
Author(s):  
Kevin Arceneaux
Keyword(s):  
Decision Making ◽  
Individual Differences ◽  
Cognitive Processes ◽  
Evolutionary History ◽  
Behavioral Responses ◽  
History Of ◽  
Economic Beliefs

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.

The role of a family history of adenocarcinomas in patients with Barrett oesophagus

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
P TSIBOURIS ◽  
M HENDRICKSE ◽  
P ISAACS
Keyword(s):  
Family History ◽  
History Of ◽  
Barrett Oesophagus

Protective Factors and Suicidality in Members of Arab Kindred

Crisis ◽  
2012 ◽  
Vol 33 (2) ◽  
pp. 80-86 ◽  
Author(s):  
Sami Hamdan ◽  
Nadine Melhem ◽  
Israel Orbach ◽  
Ilana Farbstein ◽  
Mohammad El-Haib ◽  
...  
Keyword(s):  
Risk Factors ◽  
Protective Factors ◽  
Suicidal Behavior ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Suicidal Risk ◽  
Arab Population ◽  
Psychiatric Interview ◽  
History Of

Background: Relatively little is known about the role of protective factors in an Arab population in the presence of suicidal risk factors. Aims: To examine the role of protective factors in a subsample of in large Arab Kindred participants in the presence of suicidal risk factors. Methods: We assessed protective and risk factors in a sample of 64 participants (16 suicidal and 48 nonsuicidal) between 15 and 55 years of age, using a comprehensive structured psychiatric interview, the Composite International Diagnostic Interview (CIDI), self-reported depression, anxiety, hopelessness, impulsivity, hostility, and suicidal behavior in first-degree and second-relatives. We also used the Religiosity Questionnaire and suicide attitude (SUIATT) and multidimensional perceived support scale. Results: Suicidal as opposed to nonsuicidal participants were more likely to have a lifetime history of major depressive disorder (MDD) (68.8% vs. 22.9% χ2 = 11.17, p = .001), an anxiety disorder (87.5% vs. 22.9, χ2 = 21.02, p < .001), or posttraumatic stress disorder (PTSD) (25% vs. 0.0%, Fisher’s, p = .003). Individuals who are otherwise at high risk for suicidality have a much lower risk when they experience higher perceived social support (3.31 ± 1.36 vs. 4.96 ± 1.40, t = 4.10, df = 62, p < .001), and they have the view that suicide is somehow unacceptable (1.83 ± .10 vs. 1.89 ± .07, t = 2.76, df = 60, p = .008). Conclusions: Taken together with other studies, these data suggest that the augmentation of protective factors could play a very important role in the prevention of incidental and recurrent suicidal behavior in Arab populations, where suicidal behavior in increasing rapidly.

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