Tyrosine-Derived Novel Benzoxazine Active in a Rat Syngenic Mammary Tumor Model of Breast Cancer

2021 ◽  
Author(s):  
Amit Kumar Jana ◽  
Jyotsana Singh ◽  
Asha Ganesher ◽  
Amit Kumar ◽  
Arpita Banerjee ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mammary Tumor ◽  
Tumor Model ◽  
Mammary Tumor Model

scholarly journals Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Begüm Utz ◽  
Rita Turpin ◽  
Johanna Lampe ◽  
Jeroen Pouwels ◽  
Juha Klefström
Keyword(s):  
Breast Cancer ◽  
Mammary Tumor ◽  
Tumor Model ◽  
Primary Tumors ◽  
T Cell Infiltration ◽  
Cancer Models ◽  
Mouse Mammary Tumor ◽  
Mammary Tumor Model ◽  
Metastatic Process ◽  
Mouse Mammary Tumor Model

Abstract Breast cancer is the most common form of cancer in women. Despite significant therapeutic advances in recent years, breast cancer also still causes the greatest number of cancer-related deaths in women, the vast majority of which (> 90%) are caused by metastases. However, very few mouse mammary cancer models exist that faithfully recapitulate the multistep metastatic process in human patients. Here we assessed the suitability of a syngrafting protocol for a Myc-driven mammary tumor model (WAP-Myc) to study autochthonous metastasis. A moderate but robust spontaneous lung metastasis rate of around 25% was attained. In addition, increased T cell infiltration was observed in metastatic tumors compared to donor and syngrafted primary tumors. Thus, the WAP-Myc syngrafting protocol is a suitable tool to study the mechanisms of metastasis in MYC-driven breast cancer.

scholarly journals T-cadherin Supports Angiogenesis and Adiponectin Association with the Vasculature in a Mouse Mammary Tumor Model

2008 ◽  
Vol 68 (5) ◽  
pp. 1407-1416 ◽  
Author(s):  
Lionel W. Hebbard ◽  
Michèle Garlatti ◽  
Lawrence J.T. Young ◽  
Robert D. Cardiff ◽  
Robert G. Oshima ◽  
...  
Keyword(s):  
Mammary Tumor ◽  
Tumor Model ◽  
Mouse Mammary Tumor ◽  
Mammary Tumor Model ◽  
Mouse Mammary Tumor Model

Ultrasound Molecular Imaging With BR55, a Predictive Tool of Antiangiogenic Treatment Efficacy in a Chemo-Induced Mammary Tumor Model

2020 ◽  
Vol 55 (10) ◽  
pp. 657-665 ◽  
Author(s):  
Alexandre Helbert ◽  
Mathew Von Wronski ◽  
Delphine Colevret ◽  
Catherine Botteron ◽  
Frederic Padilla ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Mammary Tumor ◽  
Treatment Efficacy ◽  
Tumor Model ◽  
Predictive Tool ◽  
Antiangiogenic Treatment ◽  
Mammary Tumor Model ◽  
Ultrasound Molecular Imaging

scholarly journals Investigation into the cancer protective effect of flaxseed in Tg.NK (MMTV/c-neu) mice, a murine mammary tumor model

2011 ◽  
Vol 6 (4) ◽  
pp. 403-411 ◽  
Author(s):  
Franziska Kramer Birkved ◽  
Alicja Mortensen ◽  
José L. Peñalvo ◽  
Rikke H. Lindecrona ◽  
Ilona Kryspin Sørensen
Keyword(s):  
Protective Effect ◽  
Mammary Tumor ◽  
Tumor Model ◽  
Murine Mammary Tumor ◽  
Mammary Tumor Model
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