Catalyst-Free Cyclization- and Curtius Rearrangement-Induced Functional Group Transformation: An Improved Synthetic Strategy of First-in-Class ATX Inhibitor Ziritaxestat (GLPG-1690)

2020 ◽  
Vol 24 (6) ◽  
pp. 997-1005
Author(s):  
Hongrui Lei ◽  
Yu Yang ◽  
Changtao Li ◽  
Fang Jia ◽  
Nan Jiang ◽  
...  
Keyword(s):  
Functional Group ◽  
Curtius Rearrangement ◽  
Group Transformation ◽  
Catalyst Free ◽  
Synthetic Strategy ◽  
Functional Group Transformation

Selective electrocatalytic hydroboration of aryl alkenes

2021 ◽  
Author(s):  
Yahui Zhang ◽  
Xiangyu Zhao ◽  
Ce Bi ◽  
Wenqi Lu ◽  
Mengyuan Song ◽  
...  
Keyword(s):  
Potential Application ◽  
Functional Group ◽  
Group Transformation ◽  
Functional Group Transformation ◽  
Great Potential Application

A CH3CN-involved electrochemical mono- or di-functional borylation reaction with alkenes and HBpin as substrates was reported. Functional group transformation and gram-scale synthesis demonstrated the utility of this method and showed great potential application.

Functional group transformation of perfluoroadamantane derivatives

2006 ◽  
Vol 127 (8) ◽  
pp. 1125-1129 ◽  
Author(s):  
Koichi Murata ◽  
Shu-Zhong Wang ◽  
Yoshitomi Morizawa ◽  
Kazuya Oharu
Keyword(s):  
Functional Group ◽  
Group Transformation ◽  
Functional Group Transformation

FUNCTIONAL GROUP TRANSFORMATION. CONVERSION OF ALDEHYDES INTO AMIDESVIAα-CYANOENAMINES

1978 ◽  
Vol 10 (3) ◽  
pp. 149-156 ◽  
Author(s):  
Nobert De Kimpe ◽  
Roland Verhé ◽  
Laurent De Buyck ◽  
Jan Chys ◽  
Niceas Schamp
Keyword(s):  
Functional Group ◽  
Group Transformation ◽  
Functional Group Transformation
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