Solid-Phase Synthesis of Mesoporous ZnO Using Lignin-Amine Template and Its Photocatalytic Properties

2014 ◽  
Vol 53 (16) ◽  
pp. 6585-6592 ◽  
Author(s):  
Xiaohong Wang ◽  
Yike Zhang ◽  
Chen Hao ◽  
Feng Feng ◽  
Henbo Yin ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Photocatalytic Properties ◽  
Phase Synthesis ◽  
Mesoporous Zno ◽  
Lignin Amine

Solid Phase Synthesis of Xanthene Derivatives Assisted By Imidazolium Salts

2018 ◽  
Vol 5 (1) ◽  
pp. 19-25
Author(s):  
Ganapathi Pandurangan ◽  
Ganesan Kilivelu
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Imidazolium Salts ◽  
Phase Synthesis ◽  
Xanthene Derivatives

Synthesis and Screening of A DNA-Encoded Library of Non-Peptidic Macrocycles

2020 ◽  
Author(s):  
Eric Koesema ◽  
Animesh Roy ◽  
Nicholas G. Paciaroni ◽  
Thomas Kodadek
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Cell Permeability ◽  
Phase Synthesis ◽  
Protein Ligands ◽  
High Affinity ◽  
Scaffold Diversity

There is considerable interest in the development of libraries of non-peptidic macrocycles as a source of ligands for difficult targets. We report here the solid-phase synthesis of a DNA-encoded library of several hundred thousand thioether-linked macrocycles. The library was designed to be highly diverse with respect to backbone scaffold diversity and to minimize the number of amide N-H bonds, which compromise cell permeability. The utility of the library as a source of protein ligands is demonstrated through the isolation of compounds that bind streptavidin, a model target, with high affinity.

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