Novel Nonsteroidal Antiinflammatory Drugs Possessing a Nitric Oxide Donor Diazen-1-ium-1,2-diolate Moiety:  Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Faculty Opinions recommendation of Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011708.323215 ◽

2005 ◽

Author(s):

Larry K Keefer

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nonsteroidal Antiinflammatory Drugs ◽

Nitric Oxide Donor ◽

Antiinflammatory Drugs ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies

Second-Generation Aspirin and Indomethacin Prodrugs Possessing anO2-(Acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate Nitric Oxide Donor Moiety: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Journal of Medicinal Chemistry ◽

10.1021/jm701450q ◽

2008 ◽

Vol 51 (6) ◽

pp. 1954-1961 ◽

Cited By ~ 45

Author(s):

Carlos A. Velázquez ◽

Qiao-Hong Chen ◽

Michael L. Citro ◽

Larry K. Keefer ◽

Edward E. Knaus

Keyword(s):

Nitric Oxide ◽

Second Generation ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies ◽

Design, synthesis, biological evaluation, and nitric-oxide release studies of a novel series of celecoxib prodrugs possessing a nitric-oxide donor moiety

Brazilian Journal of Pharmaceutical Sciences ◽

10.1590/s2175-97902018000417281 ◽

2018 ◽

Vol 54 (4) ◽

Author(s):

Wael Mohamed Soliman ◽

Khaled Rashad Ahmed Abdellatif ◽

Edward Elmer Knaus

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies ◽

Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies

10.1016/j.bmcl.2016.04.068 ◽

2016 ◽

Vol 26 (12) ◽

pp. 2795-2800 ◽

Cited By ~ 20

Author(s):

Shengtao Xu ◽

Guangyu Wang ◽

Yan Lin ◽

Yanju Zhang ◽

Lingling Pei ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies ◽

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2008.10.001 ◽

2008 ◽

Vol 16 (22) ◽

pp. 9694-9698 ◽

Cited By ~ 25

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Carlos Velázquez ◽

Dipankar Das ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Analog Synthesis ◽

Release Studies ◽

Ester Prodrugs

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.05.046 ◽

2009 ◽

Vol 17 (14) ◽

pp. 5182-5188 ◽

Cited By ~ 21

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Dipankar Das ◽

Gang Yu ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Analog Synthesis ◽

Release Studies ◽

Ester Prodrugs

Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: Synthesis, biological evaluation and nitric oxide release studies

10.1016/j.bmcl.2009.04.059 ◽

2009 ◽

Vol 19 (11) ◽

pp. 3014-3018 ◽

Cited By ~ 30

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Dipankar Das ◽

Gang Yu ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Release Studies ◽

Ester Prodrugs

Novel Nitric Oxide-Releasing Derivatives of Brusatol as Anti-Inflammatory Agents: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Journal of Medicinal Chemistry ◽

10.1021/jm5007534 ◽

2014 ◽

Vol 57 (18) ◽

pp. 7600-7612 ◽

Cited By ~ 39

Author(s):

Weibin Tang ◽

Jianlin Xie ◽

Song Xu ◽

Haining Lv ◽

Mingbao Lin ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies ◽

Anti Inflammatory ◽

Nitric Oxide Releasing ◽

Derivatives Of

Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Synthesis, biological evaluation and nitric oxide release studies

10.1016/j.bmcl.2010.06.022 ◽

2010 ◽

Vol 20 (15) ◽

pp. 4544-4549 ◽

Cited By ~ 25

Author(s):

Khaled R.A. Abdellatif ◽

Morshed A. Chowdhury ◽

Carlos A. Velázquez ◽

Zhangjian Huang ◽

Ying Dong ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Release Studies ◽

Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: Synthesis, biological evaluation and nitric oxide release studies

10.1016/j.bmcl.2010.01.014 ◽

2010 ◽

Vol 20 (4) ◽

pp. 1324-1329 ◽

Cited By ~ 45

Author(s):

Morshed A. Chowdhury ◽

Khaled R.A. Abdellatif ◽

Ying Dong ◽

Gang Yu ◽

Zhangjian Huang ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Release Studies ◽