Obesity considerations during the COVID-19 outbreak

2021 ◽  
pp. 1-13
Author(s):  
François Dohet ◽  
Suva Loap ◽  
Alain Menzel ◽  
Mohammed Iddir ◽  
Frédéric Dadoun ◽  
...  
Keyword(s):  
Productivity Loss ◽  
Obesity Paradox ◽  
Double Burden ◽  
Angiotensin Converting Enzyme 2 ◽  
Worldwide Population ◽  
Related Risk ◽  
The Relationship ◽  
Weight Management Programs ◽  
Activation Component ◽  
Lifestyle Patterns

Abstract. The worldwide population is facing a double burden of epidemic, the COVID-19 and obesity. This is even more alarming as obesity increases the COVID-19 severity. However, the relationship between obesity and COVID-19 severity is more complex than a simple association with BMI. In particular, obesity has been associated with low death rates in patients with acute respiratory distress syndrome, a fatal comorbidity to COVID-19, possibly due to the obesity paradox. Also, visceral adiposity could be a major risk factor for COVID-19 severity, due to its immune activation component, release of angiotensin-converting enzyme 2 and involvement in the cytokine storm, hypercoagulability and embolism. A poor antioxidant nutritional status also weakens the immune system, increasing inflammation and infection risk. Moreover, the COVID-19 lockdown might impact lifestyle patterns, mental health and weight bias, worsening the obesity then COIVD-19 situation. On the other hand, health care expenses and productivity loss are expected to increase during the concomitant epidemics. The co-occurrence of obesity and COVID-19 is a major challenge at both public health and economic levels that should urgently be taken into consideration. The identification of COVID-19 weight related risk factors and the development of appropriate weight management programs are needed to tackle the concomitant epidemics.

Associação entre obesidade e resultados graves do tratamento em pacientes com COVID-19

2021 ◽  
Vol 12 (47) ◽  
pp. 138-142
Author(s):  
Giordana Gregório Fritsch ◽  
Michael Wesley Schmidt ◽  
Antônio Carlos Gargioni Filho ◽  
Hussein Nasser Fares
Keyword(s):  
Metabolic Disorders ◽  
Distress Syndrome ◽  
Obesity Paradox ◽  
Low Grade ◽  
Double Burden ◽  
Death Rates ◽  
Worldwide Population ◽  
Low Grade Inflammation ◽  
The Relationship ◽  
Activation Component

The worldwide population is facing a double burden of epidemic, the COVID-19and obesity. This is even more alarming as obesity increases the COVID-19 severity. However, the relationship between obesity and COVID-19 severity is more complex than a simple association with BMI. In particular, obesity has been associated with low death rates in patients with acute respiratory distress syndrome, a fatal comorbidity to COVID-19, possibly due to the obesity paradox. Also, visceral adiposity could be a major risk factor for COVID- -19severity, due to its immune activation component, release of ACE2 and involvement in the cytokine storm, It is also known to correlate with metabolic disorders, low-grade inflammation and higher mortality rates.

scholarly journals ACE2 Is an Adjacent Element of Atherosclerosis and COVID-19 Pathogenesis

2021 ◽  
Vol 22 (9) ◽  
pp. 4691
Author(s):  
Anastasia V. Poznyak ◽  
Evgeny E. Bezsonov ◽  
Ali H. Eid ◽  
Tatyana V. Popkova ◽  
Ludmila V. Nedosugova ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Renin Angiotensin System ◽  
Myocardial Damage ◽  
Angiotensin Converting Enzyme 2 ◽  
Adjacent Element ◽  
Chinese Province ◽  
Coronavirus Infection ◽  
First Time ◽  
The Relationship ◽  
Interspecies Barrier

COVID-19 is a highly contagious new infection caused by the single-stranded RNA Sars-CoV-2 virus. For the first time, this infection was recorded in December 2019 in the Chinese province of Wuhan. The virus presumably crossed the interspecies barrier and passed to humans from a bat. Initially, the disease was considered exclusively in the context of damage to the respiratory system, but it quickly became clear that the disease also entails serious consequences from various systems, including the cardiovascular system. Among these consequences are myocarditis, myocardial damage, subsequent heart failure, myocardial infarction, and Takotsubo syndrome. On the other hand, clinical data indicate that the presence of chronic diseases in a patient aggravates the course and outcome of coronavirus infection. In this context, the relationship between COVID-19 and atherosclerosis, a condition preceding cardiovascular disease and other disorders of the heart and blood vessels, is particularly interesting. The renin-angiotensin system is essential for the pathogenesis of both coronavirus disease and atherosclerosis. In particular, it has been shown that ACE2, an angiotensin-converting enzyme 2, plays a key role in Sars-CoV-2 infection due to its receptor activity. It is noteworthy that this enzyme is important for the normal functioning of the cardiovascular system. Disruptions in its production and functioning can lead to various disorders, including atherosclerosis.

Lifestyle in urology: Benign diseases

2021 ◽  
pp. 039156032199438
Author(s):  
Riccardo Bientinesi ◽  
Carlo Gandi ◽  
Luigi Vaccarella ◽  
Emilio Sacco
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Social Impact ◽  
Clinical Evidence ◽  
Prostatic Hyperplasia ◽  
Benign Diseases ◽  
Related Risk ◽  
The Social ◽  
The Relationship ◽  
Urological Diseases

Modifiable lifestyle-related risk factors are the object of increasing attention, with a view to primary and tertiary prevention, to limit the onset and development of diseases. Also in the urological field there is accumulating evidence of the relationship between urological diseases and lifestyle-related risk factors that can influence their incidence and prognosis. Risk factors such as nutrition, physical activity, sexual habits, tobacco smoking, or alcohol consumption can be modified to limit morbidity and reduce the social impact and the burdensome costs associated with diagnosis and treatment. This review synthesizes the current clinical evidence available on this topic, trying to satisfy the need for a summary on the relationships between the most important lifestyle factors and the main benign urological diseases, focusing on benign prostatic hyperplasia (BPH), infections urinary tract (UTI), urinary incontinence (UI), stones, erectile dysfunction, and male infertility.

scholarly journals 29.E. Workshop: Data analysis, advocacy activities, and actions to counteract the double burden of malnutrition

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
◽  
Keyword(s):  
Risk Factors ◽  
Global Health ◽  
Chronic Diseases ◽  
World Health ◽  
Special Focus ◽  
Global Level ◽  
Double Burden ◽  
Related Risk ◽  
Double Burden Of Malnutrition ◽  
The Impact

Abstract The burden of non-communicable chronic diseases (NCDs) represents a public health issue of gigantic proportion at global level. Among others, diet has been demonstrated to be a key element to maintain health and prevent NCDs. Today's world is facing the so-called “double burden of malnutrition”, characterized by the coexistence of undernutrition along with overweight, obesity or diet-related NCDs due to a substantial shift toward unhealthy diet high in sugars and ultra-processed foods and concomitant inadequate accessibility of nutritious foods. While interventions to improve diet quality and nutrition knowledge are of paramount importance in order to decrease the burden of NCDs over the next decades, the international policy framework should aim to develop evidence-based policy approaches to reduce such burden globally. In this context, the EUPHA Food and nutrition section, the EUPHA Chronic diseases section, the EUPHA Health promotion section, in collaboration with the World Health Organization (WHO), aim to propose a joint workshop to provide the latest updates from leading scientists and experts involved in global health research, with a special focus on NCDs, obesity and nutrition-related risk factors as well as ongoing interventions aimed to reduce the double burden of malnutrition. The objectives of the present workshop are the following: To quantify the global burden and temporal trends of NCDs risk factors; To assess the impact of nutrition-related risk factors on NCDs; To provide examples of advocacy activities and actions at global level to improve nutrition education and dietary behaviors; To promote translatable information at global level and drive implementation of knowledge into policy and practice. Organizing the present workshop would provide an important occasion for gathering experts in the field and sharing opinions with the audience in light of the presented results. Given the many actors involved, the workshop will provide a unique occasion to discuss about potential policy approaches in the context of the conference. Key messages There is science-based evidence demonstrating that healthy nutrition is a key factor to maintain global health and prevent chronic non-communicable diseases. Governmental and non-governmental efforts are currently working to counteract malnutrition worldwide.

Healthcare Management During a Pandemic: The Other Side of the Coin for the Treatment of Covid-19 Infection

2021 ◽  
Vol 21 ◽  
Author(s):  
Danila De Vito ◽  
Antonio Fusco ◽  
Caterina Benincasa ◽  
Luca Laghi ◽  
Francesco M. Ceruso
Keyword(s):  
Healthcare Systems ◽  
Healthcare Management ◽  
World Health ◽  
Industrialized Countries ◽  
Negative Effects ◽  
Positive Effects ◽  
Worldwide Population ◽  
Related Risk ◽  
The Social ◽  
Health Organization

Background: World Health Organization (WHO) has increasingly improved the guidelines to tackle the spread of Coronavirus Disease 2019 (COVID-19) among the worldwide population. In this context, each country has introduced specific social, healthcare, political and macroeconomic measures to face COVID pandemic locally. Objective: The general aim of this comparative overview is to highlight the most significant effects of COVID-19 pandemic on the main healthcare systems. Also, we critically analyzed the macroeconomic variables and the most promising solutions to improve both healthcare system and its related risk management, taking into specific consideration the most industrialized countries. Method: The main strategy has been built on a renewed concept of the hospital, rebuilding the old concepts of “triage” and “intensive care”. Recently, COVID-19 hospitals have allowed to cater the patients affected by COVID-19. Moreover, the reshaping of several healthcare policies and requirements has led to several positive effects, such as the recruitment of a huge number of human resources in the healthcare systems. Nevertheless, several negative effects have also impacted the communities mostly subjected to infections. Conclusion: Undoubtedly, the national healthcare systems have somehow addressed the people’s needs, trying not to neglect the social, healthcare, economic and political aspects. In our overview, we have reported how the different actions taken in the last months, have resulted in different outcomes.

The Comparison of Susceptibility to SARS-CoV-2 Infection between Pediatric and Adults

2021 ◽  
Author(s):  
Milad Zandi ◽  
Saber Soltani ◽  
Mona Fani ◽  
Haniye Shafipour ◽  
Samaneh Abbasi
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Mortality Rate ◽  
Age Groups ◽  
Severe Illness ◽  
Converting Enzyme ◽  
Angiotensin Converting Enzyme 2 ◽  
The World ◽  
Smoking Susceptibility ◽  
The Relationship

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.

scholarly journals Evaluation of Neospora caninum-Associated Abortion in a Seroepidemiological Study of Cattles Using IFAT Method

2020 ◽  
Vol 1 (1) ◽  
pp. 7-10
Author(s):  
Seyed Razi Bahavarnia ◽  
Pedram Ahli ◽  
Arash Rasouli
Keyword(s):  
Neospora Caninum ◽  
Farming System ◽  
Chi Square ◽  
Related Risk ◽  
Coccidian Parasites ◽  
Chi Square Test ◽  
Relationship Of ◽  
Cattle Farms ◽  
The Relationship

Background: Neospora caninum is a cyst forming coccidian parasites and one of the important factors in abortion of cows and neurologic disease in dogs around the world. This study was conducted to investigate the seroprevalence of N. caninum in dairy cows of Tabriz city using immunofluorescence method and related risk factors. Methods: In this study conducted in 2018, 100 samples from industrial cattle farms and 100 samples from traditional cattle farms of Tabriz were randomly collected. By fixing tachyzoites cultured in a culture medium, the kit was prepared in this study and the slides were examined by fluorescence microscopy (Zeiss). The results obtained in relation to the study variables (type of farming system, age, contact with dogs, and abortion history) were analyzed using SPSS software and chi-square test. Results: Neospora caninum antibodies were detected in 33 samples (16.5%). The relationship of positive serums with abortion and contact with dogs was significant statistically (P<0.05). Conclusions: Due to the significant relationship of infection rate in cows with abortion history and contact with dogs, further studies are needed to determine the exact role of Neospora in abortion of cows.

How Serious Is Debt Among Probation Clients? A Study Into the Prevalence and Scope of Debt in a Dutch Probation Sample

2020 ◽  
pp. 0306624X2098103
Author(s):  
Gercoline van Beek ◽  
Vivienne de Vogel ◽  
Dike van de Mheen
Keyword(s):  
Risk Factors ◽  
Risk Assessment ◽  
Reciprocal Relationship ◽  
Assessment Data ◽  
Living Situation ◽  
Related Risk ◽  
Probation Service ◽  
The Relationship ◽  
Mental And Physical Health ◽  
Underlying Risk

Although studies point to a relationship between debt and crime, there is a limited understanding of their reciprocal relationship and possible mediating risk factors. Moreover, knowledge about the prevalence and scope of debt among offenders is lacking. Therefore, the present study analyzed 250 client files including risk assessment data from the Dutch probation service on the prevalence of debt and possibly related risk factors. The results show that debt is highly prevalent and complex, which underlines the importance of acquiring more knowledge about debt as a potential risk factor for relapse during supervision. It was found that problems with regard to childhood and living situation, education and work/daytime activities, and mental and physical health may be possible underlying risk factors in the relationship between debt and crime. These insights can help professionals adequately support clients with regard to debt in order to prevent recidivism.

Quantifying effects of accidents by fuzzy-logic- and simulation-based analysis

2006 ◽  
Vol 33 (3) ◽  
pp. 219-226 ◽  
Author(s):  
Sangyoub Lee ◽  
Daniel W Halpin ◽  
Hoon Chang
Keyword(s):  
Fuzzy Logic ◽  
Simulation Analysis ◽  
Productivity Loss ◽  
Indirect Costs ◽  
Safety Factors ◽  
Logic Simulation ◽  
Training And Supervision ◽  
Simulation Based ◽  
The Relationship ◽  
Productive Time

This study quantifies the effects of accidents by defining one of the indirect costs, the productive time lost owing to accidents in utility trenching operations. The probability of accidents, estimated by fuzzy-logic-based analysis of the performance of the factors (training, supervision, and preplanning) affecting safety in utility trenching operations, was used to quantify, based on simulation analysis, the productivity loss due to process delays resulting from accidents during excavation and pipe installation. It was determined that the productivity loss resulting from accidents during excavation is greater than that resulting from accidents during pipe installation. During excavation, the "very poor" condition of preplanning is most critical to productivity loss due to accidents, whereas during pipe installation, the condition of training and supervision affects the productivity loss more than that of preplanning. This paper provides insights into the relationship between the condition of the safety factors and the possible productivity loss by concomitant probability of accidents to quantify the effects of the accidents.Key words: effect of accidents, probability of accidents, productivity, fuzzy logic, simulation.

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