scholarly journals Mig-2 attenuates cisplatin-induced apoptosis of human glioma cells in vitro through AKT/JNK and AKT/p38 signaling pathways

2014 ◽  
Vol 35 (9) ◽  
pp. 1199-1206 ◽  
Author(s):  
Yun-wei Ou ◽  
Zi-tong Zhao ◽  
Chuan-yue Wu ◽  
Bai-nan Xu ◽  
Yong-mei Song ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Glioma Cells ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Induced Apoptosis

scholarly journals Migfilin sensitizes cisplatin-induced apoptosis in human glioma cells in vitro

2012 ◽  
Vol 33 (10) ◽  
pp. 1301-1310 ◽  
Author(s):  
Jing Fan ◽  
Yun-wei Ou ◽  
Chuan-yue Wu ◽  
Chun-jiang Yu ◽  
Yong-mei Song ◽  
...  
Keyword(s):  
Glioma Cells ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Induced Apoptosis

Metastasis tumor-associated protein-2 knockdown suppresses the proliferation and invasion of human glioma cells in vitro and in vivo

2014 ◽  
Vol 120 (2) ◽  
pp. 273-281 ◽  
Author(s):  
Chun-Yuan Cheng ◽  
Ying-Erh Chou ◽  
Chung-Po Ko ◽  
Shun-Fa Yang ◽  
Shu-Ching Hsieh ◽  
...  
Keyword(s):  
Glioma Cells ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Proliferation And Invasion

scholarly journals Data analyses of honokiol-induced autophagy of human glioma cells in vitro and in vivo

Data in Brief ◽  
2016 ◽  
Vol 9 ◽  
pp. 667-672 ◽  
Author(s):  
Gong-Jhe Wu ◽  
Chien-Ju Lin ◽  
Yung-Wei Lin ◽  
Ruei-Ming Chen
Keyword(s):  
Glioma Cells ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Data Analyses

PAX3 Promotes Proliferation of Human Glioma Cells by WNT/β-Catenin Signaling Pathways

2019 ◽  
Vol 68 (1) ◽  
pp. 66-77 ◽  
Author(s):  
Xia Liang ◽  
Zhao Dong ◽  
Wu Bin ◽  
Nie Dekang ◽  
Zhu Xuhang ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Glioma Cells ◽  
Human Glioma ◽  
Human Glioma Cells

Licochalcone A inhibits the invasive potential of human glioma cells by targeting the MEK/ERK and ADAM9 signaling pathways

2018 ◽  
Vol 9 (12) ◽  
pp. 6196-6204 ◽  
Author(s):  
Chien-Feng Huang ◽  
Shun-Fa Yang ◽  
Hui-Ling Chiou ◽  
Wen-Hung Hsu ◽  
Jen-Chieh Hsu ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Glioma Cells ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Invasive Potential ◽  
Licochalcone A ◽  
Antitumor Properties

Licochalcone A (LicA) has been reported to possess antitumor properties.

Altered in vitro spreading and cytoskeletal organization in human glioma cells by downregulation of urokinase receptor

1997 ◽  
Vol 20 (4) ◽  
pp. 355-365 ◽  
Author(s):  
Shravan K. Chintala ◽  
Sanjeeva Mohanam ◽  
Yoshinori Go ◽  
Boyapati Venkaiah ◽  
Raymond Sawaya ◽  
...  
Keyword(s):  
Glioma Cells ◽  
Urokinase Receptor ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Cytoskeletal Organization

scholarly journals Inhibition of cell proliferation by 2-fluorobenzaldehyde retinoic acid conjugate through suppression of STAT3 activation in human glioma cells

2015 ◽  
Vol 10 (4) ◽  
pp. 966
Author(s):  
Ji-Heng Hao ◽  
Dian-Feng Hu ◽  
Li-Mei Mao ◽  
Shi-Gang Zhang ◽  
Ji-Yue Wang ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Glioma Cells ◽  
Inhibitory Effect ◽  
Human Glioma ◽  
Human Glioma Cells ◽  
Expression Of Genes ◽  
Acid Conjugate ◽  
G0 Phase ◽  
Induced Apoptosis ◽  
Endothelial Growth Factor

<p class="Abstract">The present study was performed to investigate the effect of 2-fluorobenzaldehyde retinoic acid conjugate on activation of STAT3 pathway in human glioma cells. The results revealed that the compound exhibited inhibitory effect on the activation of STAT3 induced constitutively and by interleukin-6. The inhibitory effect on STAT3 activation was found to be concentration- and time-dependent. In U373 glioma cells, 2-fluorobenzaldehyde retinoic acid conjugate treatment caused a significant enhancement in the expression of proapoptotic proteins like Bax and Bak. Its treatment inhibited the expression of genes including, cyclin D1, Bcl-2, Bcl-xL, survivin, Mcl-1, and vascular endothelial growth factor (VEGF) in U373 glioma cells. Furthermore, the conjugate inhibited proliferation, induced apoptosis and caused accumulation of cells in G1-G0 phase of cell cycle. Thus, 2-fluorobenzaldehyde retinoic acid conjugate acts as a potent inhibitor of STAT3 activation that can be promising importance for the prevention and treatment of gliomas.</p><p> </p>

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