Neural network computation with DNA strand displacement cascades

Nature ◽  
2011 ◽  
Vol 475 (7356) ◽  
pp. 368-372 ◽  
Author(s):  
Lulu Qian ◽  
Erik Winfree ◽  
Jehoshua Bruck
IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 100428-100441
Author(s):  
Nelson E. Ordonez-Guillen ◽  
Israel M. Martinez-Perez

ACS Nano ◽  
2014 ◽  
Vol 8 (8) ◽  
pp. 8487-8496 ◽  
Author(s):  
Mario Teichmann ◽  
Enzo Kopperger ◽  
Friedrich C. Simmel

NANO ◽  
2020 ◽  
pp. 2150001
Author(s):  
Siyan Zhu ◽  
Qiang Zhang

The ability of neural networks to process information intelligently has allowed them to be successfully applied in the fields of information processing, controls, engineering, medicine, and economics. The brain-like working mode of a neural network gives it incomparable advantages in solving complex nonlinear problems compared with other methods. In this paper, we propose a feedforward DNA neural network framework based on an enzyme-free, entropy-driven DNA reaction network that uses a modular design. A multiplication gate, an addition gate, a subtraction gate, and a threshold gate module based on the DNA strand displacement principle are cascaded into a single DNA neuron, and the neuron cascade is used to form a feedforward transfer neural network. We use this feedforward neural network to realize XOR logic operation and full adder logic operation, which proves that the molecular neural network system based on DNA strand displacement can carry out complex nonlinear operation and reflects the powerful potential of building these molecular neural networks.


2017 ◽  
Vol 121 (12) ◽  
pp. 2594-2602 ◽  
Author(s):  
Xiaoping Olson ◽  
Shohei Kotani ◽  
Bernard Yurke ◽  
Elton Graugnard ◽  
William L. Hughes

ChemPhysChem ◽  
2021 ◽  
Author(s):  
Hui Lv ◽  
Qian Li ◽  
Jiye Shi ◽  
Fei Wang ◽  
Chunhai Fan

Nano Letters ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 1368-1374
Author(s):  
Jinbo Zhu ◽  
Filip Bošković ◽  
Bao-Nguyen T. Nguyen ◽  
Jonathan R. Nitschke ◽  
Ulrich F. Keyser

Talanta ◽  
2019 ◽  
Vol 200 ◽  
pp. 487-493 ◽  
Author(s):  
Raja Chinnappan ◽  
Rawa Mohammed ◽  
Ahmed Yaqinuddin ◽  
Khalid Abu-Salah ◽  
Mohammed Zourob

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