Amino acid PET for brain tumours — ready for the clinic?

2016 ◽  
Vol 12 (7) ◽  
pp. 375-376 ◽  
Author(s):  
Karl-Josef Langen ◽  
Colin Watts
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Amino Acid Pet

scholarly journals Amino acid PET and MR perfusion imaging in brain tumours

2017 ◽  
Vol 5 (3) ◽  
pp. 209-223 ◽  
Author(s):  
Christian P. Filss ◽  
Francesco Cicone ◽  
Nadim Jon Shah ◽  
Norbert Galldiks ◽  
Karl-Josef Langen
Keyword(s):  
Amino Acid ◽  
Perfusion Imaging ◽  
Brain Tumours ◽  
Mr Perfusion ◽  
Mr Perfusion Imaging ◽  
Amino Acid Pet

scholarly journals Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI

2018 ◽  
Vol 45 (6) ◽  
pp. 1031-1040 ◽  
Author(s):  
N. A. da Silva ◽  
P. Lohmann ◽  
J. Fairney ◽  
A. W. Magill ◽  
A.-M. Oros Peusquens ◽  
...  
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Amino Acid Pet

scholarly journals Update on amino acid PET of brain tumours

2018 ◽  
Vol 31 (4) ◽  
pp. 354-361 ◽  
Author(s):  
Karl-Josef Langen ◽  
Norbert Galldiks
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Amino Acid Pet

Non-invasive grading of brain tumours using dynamic amino acid PET imaging : does it work for 11C-Methionine?

2007 ◽  
Vol 34 (12) ◽  
pp. 2082-2087 ◽  
Author(s):  
Gérard Moulin-Romsée ◽  
Eduard D’Hondt ◽  
Tjibbe de Groot ◽  
Jan Goffin ◽  
Raf Sciot ◽  
...  
Keyword(s):  
Amino Acid ◽  
Pet Imaging ◽  
Brain Tumours ◽  
Non Invasive ◽  
Amino Acid Pet

scholarly journals Erratum to: Amino acid PET and MR perfusion imaging in brain tumours

2017 ◽  
Vol 5 (4) ◽  
pp. 401-401
Author(s):  
Christian P. Filss ◽  
Francesco Cicone ◽  
Nadim Jon Shah ◽  
Norbert Galldiks ◽  
Karl-Josef Langen
Keyword(s):  
Amino Acid ◽  
Perfusion Imaging ◽  
Brain Tumours ◽  
Mr Perfusion ◽  
Mr Perfusion Imaging ◽  
Amino Acid Pet

Clinical value of amino acid imaging in paediatric brain tumours

2005 ◽  
Vol 44 (04) ◽  
pp. 131-136 ◽  
Author(s):  
K. Lang ◽  
S. Kloska ◽  
R. Straeter ◽  
C. H. Rickert ◽  
G. Goder ◽  
...  
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Photon Emission ◽  
Diagnostic Tools ◽  
Emission Computed Tomography ◽  
Gadolinium Enhancement ◽  
Tumour Grading ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Paediatric Brain Tumours

Summary Purpose: To evaluate single photon emission computed tomography (SPECT) using the amino acid l-3-[123I]-α-methyl tyrosine (IMT) and contrast enhanced magnetic resonance imaging (MRI) as diagnostic tools in primary paediatric brain tumours in respect of non-invasive tumour grading. Patients, materials, methods: 45 children with primary brain tumours were retrospectively evaluated. IMT uptake was quantified as tumour/nontumour- ratio, a 4-value-scale was used to measure gadolinium enhancement on contrast enhanced MRI. Statistical analyses were performed to evaluate IMT uptake and gadolinium enhancement in low (WHO I/II) and high (WHO III/ IV) grade tumours and to disclose a potential relationship of IMT uptake to disruption of blood brain barrier as measured in corresponding MRI scans. Results: IMT uptake above background level was observed in 35 of 45 patients. IMT uptake was slightly higher in high grade tumours but the difference failed to attain statistical significance. Grading of individual tumours was neither possible by IMT SPECT nor by gadolinium enhanced MRI. Conclusion: IMT is accumulated in most brain tumours in children. Tumour grading was not possible using IMT or contrast enhancement as determined by MRI. Neither morphological nor functional imaging can replace histology in paediatric brain tumours.

scholarly journals NI-29 * DIAGNOSIS OF PSEUDOPROGRESSION IN PATIENTS WITH GLIOBLASTOMA USING AMINO ACID PET

2014 ◽  
Vol 16 (suppl 5) ◽  
pp. v144-v144
Author(s):  
N. Galldiks ◽  
V. Dunkl ◽  
G. Stoffels ◽  
M. Hutterer ◽  
M. Rapp ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Pet

scholarly journals P16.10 * DIAGNOSIS OF PSEUDOPROGRESSION IN PATIENTS WITH GLIOBLASTOMA USING AMINO ACID PET

2014 ◽  
Vol 16 (suppl 2) ◽  
pp. ii80-ii80
Author(s):  
N. Galldiks ◽  
V. Dunkl ◽  
G. Stoffels ◽  
M. Hutterer ◽  
M. Rapp ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Pet
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