scholarly journals Deep convolutional neural network-based classification of cancer cells on cytological pleural effusion images

2022 ◽  
Author(s):  
Xiaofeng Xie ◽  
Chi-Cheng Fu ◽  
Lei Lv ◽  
Qiuyi Ye ◽  
Yue Yu ◽  
...  
Keyword(s):  
Neural Network ◽  
Lung Cancer ◽  
Deep Learning ◽  
Pleural Effusion ◽  
Convolutional Neural Network ◽  
Cancer Cells ◽  
Deep Convolutional Neural Network ◽  
Learning Method ◽  
Weakly Supervised

AbstractLung cancer is one of the leading causes of cancer-related death worldwide. Cytology plays an important role in the initial evaluation and diagnosis of patients with lung cancer. However, due to the subjectivity of cytopathologists and the region-dependent diagnostic levels, the low consistency of liquid-based cytological diagnosis results in certain proportions of misdiagnoses and missed diagnoses. In this study, we performed a weakly supervised deep learning method for the classification of benign and malignant cells in lung cytological images through a deep convolutional neural network (DCNN). A total of 404 cases of lung cancer cells in effusion cytology specimens from Shanghai Pulmonary Hospital were investigated, in which 266, 78, and 60 cases were used as the training, validation and test sets, respectively. The proposed method was evaluated on 60 whole-slide images (WSIs) of lung cancer pleural effusion specimens. This study showed that the method had an accuracy, sensitivity, and specificity respectively of 91.67%, 87.50% and 94.44% in classifying malignant and benign lesions (or normal). The area under the receiver operating characteristic (ROC) curve (AUC) was 0.9526 (95% confidence interval (CI): 0.9019–9.9909). In contrast, the average accuracies of senior and junior cytopathologists were 98.34% and 83.34%, respectively. The proposed deep learning method will be useful and may assist pathologists with different levels of experience in the diagnosis of cancer cells on cytological pleural effusion images in the future.

Detection and Classification of Brain Tumors from MRI Images Using a Deep Convolutional Neural Network Approach

2022 ◽  
Vol 10 (1) ◽  
pp. 0-0
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Brain Tumor ◽  
Convolutional Neural Network ◽  
Binary Classification ◽  
Deep Convolutional Neural Network ◽  
Neural Network Models ◽  
Neural Network Approach ◽  
Cancer Disease

Brain tumor is a severe cancer disease caused by uncontrollable and abnormal partitioning of cells. Timely disease detection and treatment plans lead to the increased life expectancy of patients. Automated detection and classification of brain tumor are a more challenging process which is based on the clinician’s knowledge and experience. For this fact, one of the most practical and important techniques is to use deep learning. Recent progress in the fields of deep learning has helped the clinician’s in medical imaging for medical diagnosis of brain tumor. In this paper, we present a comparison of Deep Convolutional Neural Network models for automatically binary classification query MRI images dataset with the goal of taking precision tools to health professionals based on fined recent versions of DenseNet, Xception, NASNet-A, and VGGNet. The experiments were conducted using an MRI open dataset of 3,762 images. Other performance measures used in the study are the area under precision, recall, and specificity.

scholarly journals Classification of malignancy of lung nodules in CT images using Convolutional Neural Network

2020 ◽  
Author(s):  
Giovanni Da Silva ◽  
Aristófanes Silva ◽  
Anselmo De Paiva ◽  
Marcelo Gattass
Keyword(s):  
Neural Network ◽  
Lung Cancer ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Survival Rates ◽  
Texture Features ◽  
Image Database ◽  
Lung Nodules ◽  
Learning Technique

Lung cancer presents the highest mortality rate, besides being one of the smallest survival rates after diagnosis. Thereby, early detection is extremely important for the diagnosis and treatment. This paper proposes three different architectures of Convolutional Neural Network (CNN), which is a deep learning technique, for classification of malignancy of lung nodules without computing the morphology and texture features. The methodology was tested onto the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI), with the best accuracy of 82.3%, sensitivity of 79.4% and specificity 83.8%.

scholarly journals Batik Classification using Deep Learning

2019 ◽  
Vol 8 (4) ◽  
pp. 11416-11421
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Data Analysis ◽  
Convolutional Neural Network ◽  
Image Data ◽  
High Accuracy ◽  
Learning Method ◽  
Philosophy Of Life ◽  
Proposed Model

Batik is one of the Indonesian cultural heritages that has been recognized by the global community. Indonesian batik has a vast diversity in motifs that illustrate the philosophy of life, the ancestral heritage and also reflects the origin of batik itself. Because of the manybatik motifs, problems arise in determining the type of batik itself. Therefore, we need a classification method that can classify various batik motifs automatically based on the batik images. The technique of image classification that is used widely now is deep learning method. This technique has been proven of its capacity in identifying images in high accuracy. Architecture that is widely used for the image data analysis is Convolutional Neural Network (CNN) because this architecture is able to detect and recognize objects in an image. This workproposes to use the method of CNN and VGG architecture that have been modified to overcome the problems of classification of the batik motifs. Experiments of using 2.448 batik images from 5 classes of batik motifs showed that the proposed model has successfully achieved an accuracy of 96.30%.

scholarly journals Exploration of deep-learning based classification with human SNP image graphs

2021 ◽  
Author(s):  
Chao-Hsin Chen ◽  
Kuo-Fong Tung ◽  
Wen-Chang Lin
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Deep Convolutional Neural Network ◽  
Validation Dataset ◽  
Phenotypic Traits ◽  
Human Race ◽  
Large Numbers ◽  
Image Graphs

AbstractBackgroundWith the advancement of NGS platform, large numbers of human variations and SNPs are discovered in human genomes. It is essential to utilize these massive nucleotide variations for the discovery of disease genes and human phenotypic traits. There are new challenges in utilizing such large numbers of nucleotide variants for polygenic disease studies. In recent years, deep-learning based machine learning approaches have achieved great successes in many areas, especially image classifications. In this preliminary study, we are exploring the deep convolutional neural network algorithm in genome-wide SNP images for the classification of human populations.ResultsWe have processed the SNP information from more than 2,500 samples of 1000 genome project. Five major human races were used for classification categories. We first generated SNP image graphs of chromosome 22, which contained about one million SNPs. By using the residual network (ResNet 50) pipeline in CNN algorithm, we have successfully obtained classification models to classify the validation dataset. F1 scores of the trained CNN models are 95 to 99%, and validation with additional separate 150 samples indicates a 95.8% accuracy of the CNN model. Misclassification was often observed between the American and European categories, which could attribute to the ancestral origins. We further attempted to use SNP image graphs in reduced color representations or images generated by spiral shapes, which also provided good prediction accuracy. We then tried to use the SNP image graphs from chromosome 20, almost all CNN models failed to classify the human race category successfully, except the African samples.ConclusionsWe have developed a human race prediction model with deep convolutional neural network. It is feasible to use the SNP image graph for the classification of individual genomes.

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