Circulating androgen receptor gene amplification and resistance to 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer: results of a Phase 2 trial

Phase 2 Trial ◽

Castration Resistant

MP29-05 ANDROGEN RECEPTOR GENE ABERRATIONS IN CIRCULATING CELL FREE DNA FROM JAPANESE CASTRATION RESISTANT PROSTATE CANCER PATIENTS

The Journal of Urology ◽

10.1016/j.juro.2018.02.925 ◽

2018 ◽

Vol 199 (4S) ◽

Author(s):

Takayuki Sumiyoshi ◽

Shusuke Akamatsu ◽

Toshinari Yamasaki ◽

Kei Mizuno ◽

Takayuki Goto ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Patients ◽

Receptor Gene ◽

Androgen Receptor Gene ◽

Cell Free Dna ◽

Castration Resistant ◽

Free Dna ◽

Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-14-2666 ◽

2015 ◽

Vol 21 (10) ◽

pp. 2315-2324 ◽

Cited By ~ 262

Author(s):

Arun A. Azad ◽

Stanislav V. Volik ◽

Alexander W. Wyatt ◽

Anne Haegert ◽

Stephane Le Bihan ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Gene ◽

Androgen Receptor Gene ◽

Therapeutic Resistance ◽

Cell Free Dna ◽

Castration Resistant ◽

Free Dna ◽

Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study

Annals of Oncology ◽

10.1093/annonc/mdx155 ◽

2017 ◽

Vol 28 (7) ◽

pp. 1508-1516 ◽

Cited By ~ 112

Author(s):

V. Conteduca ◽

D. Wetterskog ◽

M.T.A. Sharabiani ◽

E. Grande ◽

M.P. Fernandez-Perez ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Gene ◽

Androgen Receptor Gene ◽

Plasma Dna ◽

Castration Resistant ◽

Gene Status

Clinical utility of androgen receptor gene aberrations in circulating cell-free DNA as a biomarker for treatment of castration-resistant prostate cancer

Scientific Reports ◽

10.1038/s41598-019-40719-y ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 18

Author(s):

Takayuki Sumiyoshi ◽

Kei Mizuno ◽

Toshinari Yamasaki ◽

Yu Miyazaki ◽

Yuki Makino ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Clinical Utility ◽

Receptor Gene ◽

Androgen Receptor Gene ◽

Cell Free Dna ◽

Castration Resistant ◽

Free Dna ◽

Re: Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer

The Journal of Urology ◽

10.1016/j.juro.2015.06.049 ◽

2015 ◽

Vol 194 (3) ◽

pp. 704-704

Author(s):

Samir S. Taneja

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Gene ◽

Androgen Receptor Gene ◽

Therapeutic Resistance ◽

Cell Free Dna ◽

Castration Resistant ◽

Free Dna ◽

Faculty Opinions recommendation of [177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.739562946.793583755 ◽

2021 ◽

Author(s):

Patrick Richard

Keyword(s):

Prostate Cancer ◽

Phase 2 ◽

Open Label ◽

Phase 2 Trial ◽

Castration Resistant ◽

Open Label Phase

Olaparib combined with abiraterone in patients with metastatic castration-resistant prostate cancer: a randomised, double-blind, placebo-controlled, phase 2 trial

The Lancet Oncology ◽

10.1016/s1470-2045(18)30365-6 ◽

2018 ◽

Vol 19 (7) ◽

pp. 975-986 ◽

Cited By ~ 99

Author(s):

Noel Clarke ◽

Pawel Wiechno ◽

Boris Alekseev ◽

Nuria Sala ◽

Robert Jones ◽

...

Keyword(s):

Prostate Cancer ◽

Phase 2 ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Trial ◽

Castration Resistant

Androgen Receptor Gene Amplification in a Recurrent Prostate Cancer after Monotherapy with the Nonsteroidal Potent Antiandrogen Casodex (Bicalutamide) with a Subsequent Favorable Response to Maximal Androgen Blockade

European Urology ◽

10.1159/000474453 ◽

1997 ◽

Vol 31 (2) ◽

pp. 216-219 ◽

Cited By ~ 49

Author(s):

C. Palmberg ◽

P. Koivisto ◽

E. Hyylinen ◽

J. Isola ◽

T. Visakorpi ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Gene Amplification ◽

Receptor Gene ◽

Androgen Receptor Gene ◽

Recurrent Prostate Cancer ◽

Maximal Androgen Blockade ◽

Androgen Blockade

A Randomised Phase 2 Trial of Dexamethasone Versus Prednisolone in Castration-resistant Prostate Cancer

European Urology ◽

10.1016/j.eururo.2014.10.004 ◽

2015 ◽

Vol 67 (4) ◽

pp. 673-679 ◽

Cited By ~ 52

Author(s):

Ramachandran Venkitaraman ◽

David Lorente ◽

Vedang Murthy ◽

Karen Thomas ◽

Lydia Parker ◽

...

Keyword(s):

Prostate Cancer ◽

Phase 2 ◽

Phase 2 Trial ◽

Castration Resistant

TheraP: a randomized phase 2 trial of 177 Lu-PSMA-617 theranostic treatment vs cabazitaxel in progressive metastatic castration-resistant prostate cancer (Clinical Trial Protocol ANZUP 1603)

BJU International ◽

10.1111/bju.14876 ◽

2019 ◽

Vol 124 ◽

pp. 5-13 ◽

Cited By ~ 20

Author(s):

Michael S. Hofman ◽

Louise Emmett ◽

John Violet ◽

Alison Y. Zhang ◽

Nicola J. Lawrence ◽

...

Keyword(s):

Prostate Cancer ◽

Clinical Trial ◽

Cancer Clinical Trial ◽

Trial Protocol ◽

Phase 2 ◽

Clinical Trial Protocol ◽

Phase 2 Trial ◽

Castration Resistant ◽

Randomized Phase 2