scholarly journals Plasma virome and the risk of blood-borne infection in persons with substance use disorder

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Abraham J. Kandathil ◽  
Andrea L. Cox ◽  
Kimberly Page ◽  
David Mohr ◽  
Roham Razaghi ◽  
...  

AbstractThere is an urgent need for innovative methods to reduce transmission of bloodborne pathogens like HIV and HCV among people who inject drugs (PWID). We investigate if PWID who acquire non-pathogenic bloodborne viruses like anelloviruses and pegiviruses might be at greater risk of acquiring a bloodborne pathogen. PWID who later acquire HCV accumulate more non-pathogenic viruses in plasma than matched controls who do not acquire HCV infection. Additionally, phylogenetic analysis of those non-pathogenic virus sequences reveals drug use networks. Here we find first in Baltimore and confirm in San Francisco that the accumulation of non-pathogenic viruses in PWID is a harbinger for subsequent acquisition of pathogenic viruses, knowledge that may guide the prioritization of the public health resources to combat HIV and HCV.

2005 ◽  
Vol 32 (supplement) ◽  
pp. S11-S18 ◽  
Author(s):  
Jeffrey D. Klausner ◽  
Charlotte K. Kent ◽  
William Wong ◽  
Jacque McCright ◽  
Mitchell H. Katz

2017 ◽  
Vol 3 (1_suppl) ◽  
pp. 13S-16S ◽  
Author(s):  
Jennifer McKeever ◽  
Dorothy Evans

In 2013, the Health Resources & Services Administration redesigned the long-standing Public Health Training Center program to meet the training needs of the modern public health workforce and to implement parts of the Patient Protection and Affordable Care Act, which sets the training, recruitment, and retention of public health workers as a priority. Understanding that today’s most significant public health threats are socially constructed, resulting in chronic disease and significant years of life lost, the Health Resources & Services Administration laid the groundwork for the creation of a nationally unified network of training centers—the Public Health Learning Network (PHLN). The PHLN is the nation’s most comprehensive system of public health educators, health experts, thought leaders, and practitioners working together to advance public health training and practice. The system comprises 10 regional public health training centers, 40 local performance sites, and a National Coordinating Center for Public Health Training. The PHLN strengthens the workforce in state, local, and tribal health departments, as well as community health centers and primary care settings, to improve the capacity of a broad range of public health personnel to meet the complex public health challenges of today and tomorrow.


Author(s):  
Aikan Аkanov ◽  
Тilek Меimanaliev ◽  
Аizhan Кyzayeva ◽  
Ainur Кumar ◽  
Gulzhakhan Kashafutdinova

We have analyzed human resources in healthcare of Kazakhstan over 1985-2011, and determined general trends and regularities. By the level of provision with physicians, Kazakhstan ranks as one of the leaders in the world, at the same time there have been a deficit of physicians in the Republic over the last 20 years, particularly in rural areas. As per its regions, there is an irregularity in the physicians provision rate: the most part of specialists is concentrated in cities – Almaty and Astana, there is a deficit of physicians in the Almaty, Коstanai, North-Kazakhstan and Jambyl Oblasts. The effective use of human resources will enable to optimize expenditure for the public health and to improve the medical service quality.


2019 ◽  
Vol 23 (12) ◽  
pp. 3257-3266
Author(s):  
Sharoda Dasgupta ◽  
Dita Broz ◽  
Mary Tanner ◽  
Monita Patel ◽  
Brandon Halleck ◽  
...  

2021 ◽  
Vol 221 ◽  
pp. 108560
Author(s):  
Wilson Vincent ◽  
Jess Lin ◽  
Danielle Veloso ◽  
Desmond Miller ◽  
Willi McFarland

Author(s):  
Elizabeth Imbert ◽  
Patrick M Kinley ◽  
Ashley Scarborough ◽  
Caroline Cawley ◽  
Madeline Sankaran ◽  
...  

Abstract We report the public health response to a coronavirus disease 2019 (COVID-19) outbreak in a San Francisco shelter where 67% of residents and 17% of staff tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe the limited utility of case investigation, person-based contact tracing and symptom screening, and the benefits of mass testing in outbreak response.


2020 ◽  
Author(s):  
Rajiv Chowdhury ◽  
Shammi Luhar ◽  
Nusrat Khan ◽  
Sohel Reza Choudhury ◽  
Imran Matin ◽  
...  

To limit the social, economic and psychological damage caused by strict social distancing interventions, many low and middle-income countries (LMICs) are seeking to ease restrictions. However, it is unknown what a ‘safe reopening’ entails in LMICs given suboptimal diagnostic and surveillance capabilities. Here we discuss three community-based public health measures (sustained mitigation, zonal lockdown and dynamic rolling lockdowns) which seek to adequately balance the public health and economic priorities. Each of these options have limitations and prerequisites that may be context-specific and should be considered before implementation, including implementation and maintenance costs, social and economic costs, context-specific epidemic growth and the existing health resources.


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