Natural product anticipation through synthesis

2022 ◽  
Author(s):  
Belinda E. Hetzler ◽  
Dirk Trauner ◽  
Andrew L. Lawrence
Keyword(s):  
Natural Product

Synthetic studies toward inducamide C

2021 ◽  
Author(s):  
Ardalan A. Nabi ◽  
Lydia M. Scott ◽  
Daniel P. Furkert ◽  
Jonathan Sperry
Keyword(s):  
Natural Product ◽  
Structural Revision ◽  
Synthetic Studies

The rare benzoxazepine ring in the alkaloid inducamide C is unstable and prone to rearrangement, indicating that structural revision of the natural product may be necessary.

Lessons learned from the optimization of natural product based kinase inhibitors through molecular calculations

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
V Myrianthopoulos ◽  
P Magiatis ◽  
AL Skaltsounis ◽  
L Meijer ◽  
E Mikros
Keyword(s):  
Natural Product ◽  
Kinase Inhibitors ◽  
Lessons Learned ◽  
Molecular Calculations

New Antileishmanial Drug Leads from a Library of Natural Product Fractions Prepared by a High Throughput Fractionation Paradigm*

Planta Medica ◽  
2012 ◽  
Vol 78 (05) ◽  
Author(s):  
SK Jain ◽  
R Sahu ◽  
J Zhang ◽  
MR Jacob ◽  
XC Li ◽  
...  
Keyword(s):  
Natural Product ◽  
High Throughput ◽  
Antileishmanial Drug ◽  
Drug Leads

High throughput huaman pancreactic lipase screening of natural product library for lipase inhibition activity

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
P Jiao ◽  
J Zhao ◽  
J Yeop Lee ◽  
J Tseng-Crank ◽  
B Corneliusen ◽  
...  
Keyword(s):  
Natural Product ◽  
High Throughput ◽  
Inhibition Activity ◽  
Natural Product Library ◽  
Lipase Screening ◽  
Lipase Inhibition
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