Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)

Nature Medicine ◽

10.1038/s41591-021-01634-w ◽

2022 ◽

Author(s):

Michael J. Koren ◽

Patrick Maurice Moriarty ◽

Seth J. Baum ◽

Joel Neutel ◽

Martha Hernandez-Illas ◽

...

Keyword(s):

Phase 1 ◽

Preclinical Development ◽

Phase 1 Trial ◽

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Decision letter for "A Randomized Double-Blind Placebo-Controlled First-In-Human Phase 1 Trial of TransCon PTH in Healthy Adults"

10.1002/jbmr.4016/v3/decision1 ◽

2020 ◽

Keyword(s):

Phase 1 ◽

Healthy Adults ◽

Double Blind ◽

Double Blind Placebo ◽

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Review for "A Randomized Double-Blind Placebo-Controlled First-In-Human Phase 1 Trial of TransCon PTH in Healthy Adults"

10.1002/jbmr.4016/v1/review2 ◽

2019 ◽

Keyword(s):

Phase 1 ◽

Healthy Adults ◽

Double Blind ◽

Double Blind Placebo ◽

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A Phase 1 Trial of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With r/r DLBCL

Case Medical Research ◽

10.31525/ct1-nct04049825 ◽

2019 ◽

Author(s):

Keyword(s):

Phase 1 ◽

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A Phase 1 Trial to Evaluate the Male Reproductive Safety of Pretomanid in Healthy Volunteers

Case Medical Research ◽

10.31525/ct1-nct04179500 ◽

2019 ◽

Author(s):

Keyword(s):

Healthy Volunteers ◽

Phase 1 ◽

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Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

Case Medical Research ◽

10.31525/ct1-nct04234048 ◽

2020 ◽

Author(s):

Keyword(s):

T Cell ◽

Hodgkin Lymphoma ◽

Phase 1 ◽

Phase 1 Trial ◽

Non Hodgkin Lymphoma

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Faculty of 1000 evaluation for Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.717968952.793474542 ◽

2013 ◽

Author(s):

Nicolas Mounier

Keyword(s):

Phase 1 ◽

Cns Lymphoma ◽

Phase 1 Trial ◽

Multicenter Phase

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Faculty Opinions recommendation of Efatutazone, an oral PPAR-γ agonist, in combination with paclitaxel in anaplastic thyroid cancer: results of a multicenter phase 1 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718006667.793477593 ◽

2013 ◽

Author(s):

Luca Persani

Keyword(s):

Thyroid Cancer ◽

Phase 1 ◽

Anaplastic Thyroid Cancer ◽

Phase 1 Trial ◽

Ppar Γ ◽

Multicenter Phase

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Faculty Opinions recommendation of Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718514018.793503131 ◽

2015 ◽

Author(s):

Qing Zhong

Keyword(s):

Phase 1 ◽

Proteasome Inhibition ◽

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Faculty Opinions recommendation of Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725571445.793536699 ◽

2017 ◽

Author(s):

Ian Beales

Keyword(s):

Phase 1 ◽

Anticoagulant Effect ◽

Healthy Male ◽

Double Blind ◽

Phase 1 Trial ◽

Healthy Male Volunteers ◽

Male Volunteers

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Progesterone in Addition to Standard of Care Versus Standard of Care Alone in the Treatment of Men Admitted to the Hospital with Moderate to Severe COVID-19: A Randomised Control Phase 1 Trial

SSRN Electronic Journal ◽

10.2139/ssrn.3709835 ◽

2020 ◽

Author(s):

Sara Ghandehari ◽

Yuri Matusov ◽

Samuel Pepkowitz ◽

Donald Stein ◽

Tamana Kaderi ◽

...

Keyword(s):

Phase 1 ◽

Standard Of Care ◽

Control Phase ◽

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