scholarly journals Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Nigel Gebodh ◽  
Zeinab Esmaeilpour ◽  
Abhishek Datta ◽  
Marom Bikson
Keyword(s):  
Electrical Stimulation ◽  
Demographic Data ◽  
Transcranial Electrical Stimulation ◽  
Brain State ◽  
High Definition ◽  
Before And After ◽  
Human Participant ◽  
Cortical Regions ◽  
And Behavior ◽  
Unique Dataset

AbstractWe present a dataset combining human-participant high-density electroencephalography (EEG) with physiological and continuous behavioral metrics during transcranial electrical stimulation (tES). Data include within participant application of nine High-Definition tES (HD-tES) types, targeting three cortical regions (frontal, motor, parietal) with three stimulation waveforms (DC, 5 Hz, 30 Hz); more than 783 total stimulation trials over 62 sessions with EEG, physiological (ECG, EOG), and continuous behavioral vigilance/alertness metrics. Experiment 1 and 2 consisted of participants performing a continuous vigilance/alertness task over three 70-minute and two 70.5-minute sessions, respectively. Demographic data were collected, as well as self-reported wellness questionnaires before and after each session. Participants received all 9 stimulation types in Experiment 1, with each session including three stimulation types, with 4 trials per type. Participants received two stimulation types in Experiment 2, with 20 trials of a given stimulation type per session. Within-participant reliability was tested by repeating select sessions. This unique dataset supports a range of hypothesis testing including interactions of tDCS/tACS location and frequency, brain-state, physiology, fatigue, and cognitive performance.

Transcranial electrical stimulation devices

2021 ◽  
Author(s):  
Dennis Q. Truong ◽  
Niranjan Khadka ◽  
Angel V. Peterchev ◽  
Marom Bikson
Keyword(s):  
Electrical Stimulation ◽  
Brain Function ◽  
Computational Models ◽  
Solid Metal ◽  
Transcranial Electrical Stimulation ◽  
Waveform Generator ◽  
High Definition ◽  
Low Intensity ◽  
Support Device ◽  
Transcranial Alternating Current Stimulation

Transcranial electrical stimulation (tES) devices apply electrical waveforms through electrodes placed on the scalp to modulate brain function. This chapter describes the principles, types, and components of tES devices as well as practical considerations for their use. All tES devices include a waveform generator, electrodes, and an adhesive or headgear to position the electrodes. tES dose is defined by the size and position of electrodes, and the waveform, duration, and intensity of the current. Many sub-classes of tES are named based on dose. This chapter focuses on low intensity tES, which includes transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), and transcranial pulsed current stimulation (tPCS). tES electrode types are reviewed, including electrolyte-soaked sponge, adhesive hydrogel, high-definition, hand-held solid metal, free paste on electrode, and dry. Computational models support device design and individual targeting. The tolerability of tES is protocol specific, and medical grade devices minimize risk.

scholarly journals Repetitive Transcranial Electrical Stimulation Induces Quantified Changes in Resting Cerebral Perfusion Measured from Arterial Spin Labeling

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Matthew S. Sherwood ◽  
Aaron T. Madaris ◽  
Casserly R. Mullenger ◽  
R. Andy McKinley
Keyword(s):  
Electrical Stimulation ◽  
Prefrontal Cortex ◽  
Locus Coeruleus ◽  
Arterial Spin Labeling ◽  
Cerebral Perfusion ◽  
Spin Labeling ◽  
Direct Result ◽  
Transcranial Electrical Stimulation ◽  
Noradrenergic System ◽  
Before And After

The use of transcranial electrical stimulation (TES) as a method to augment neural activity has increased in popularity in the last decade and a half. The specific application of TES to the left prefrontal cortex has been shown to produce broad cognitive effects; however, the neural mechanisms underlying these effects remain unknown. In this work, we evaluated the effect of repetitive TES on cerebral perfusion. Stimulation was applied to the left prefrontal cortex on three consecutive days, and resting cerebral perfusion was quantified before and after stimulation using arterial spin labeling. Perfusion was found to decrease significantly more in a matched sham stimulation group than in a group receiving active stimulation across many areas of the brain. These changes were found to originate in the locus coeruleus and were broadly distributed in the neocortex. The changes in the neocortex may be a direct result of the stimulation or an indirect result via the changes in the noradrenergic system produced from the altered activity of the locus coeruleus. These findings indicate that anodal left prefrontal stimulation alters the activity of the locus coeruleus, and this altered activity may excite the noradrenergic system producing the broad behavioral effects that have been reported.

scholarly journals The effect of transcranial electrostimulation on the frontal crust of students during a psychoemotional stress

2020 ◽  
Vol 24 (1) ◽  
pp. 75-84
Author(s):  
Azamat Halidovich Kade ◽  
Caida Kazbekovna Ahejak-Naguze ◽  
Viktor Vladimirovich Durov ◽  
Yulia Viktorovna Kashina ◽  
Elena Genadevna Tacenko ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Electrical Stimulation ◽  
Frontal Cortex ◽  
Stress Resistance ◽  
Frontal Region ◽  
Transcranial Electrical Stimulation ◽  
Stress Effect ◽  
Psychoemotional Stress ◽  
Before And After ◽  
The Brain

Relevance: transcranial electrical stimulation has an anti-stress effect in humans. One of the possible mechanisms is due to changes in the functional state of the frontal region of the cerebral cortex.The aim: to evaluate the dynamics of tractography of the frontal region of the human cerebral cortex during psychoemotional stress before and after transcranial electrical stimulation. Materials and methods: Observations were performed on 26 conditionally healthy young men. Students assessed the level of stress resistance by N.N. Kirsheva, N.V. Ryabchikova and heart rate variability in the test period. Brain MRI was performed on a high-field tomograph (magnetic field strength 3 T) from General Electric (USA), followed by software processing and tractography. 16 subjects (main group) underwent transcranial electrical stimulation (TES) therapy. TES therapy was performed using the TRANSAIR-02 apparatus with monopolar impulses. Sessions were held in the evening from 18 to 22 hours every other day. The course consisted of 5 sessions of 30 minutes, the current strength was from 2.0 to 3.0 mA After a course of TES therapy, MRI of the brain and tractography were repeated. In the comparison group (10 people), TES therapy was not performed, but MRI and tractography were similarly repeated. The tractograms compared the area of the tracts in the frontal region of the cerebral cortex in both groups, as well as before and after TES therapy. For statistical analysis of the results of the study used the program: “STATISTICA 10”. Results: On the tractograms of the frontal cortex of the brain, in students experiencing stress due to the training load in the crediting period, the tract area on the tractogram was 7.9 ± 0.4 cm2. After 5 sessions of transcranial electrical stimulation, the level of stress resistance increased. On the tractograms of the frontal cortex, the area of the tracts increased and amounted to 13.4 ± 0.5 cm2.The conclusion: After transcranial electrical stimulation, when psychoemotional stress is removed, students restore paths in the frontal region of the cerebral cortex

scholarly journals Optimal use of EEG recordings to target active brain areas with transcranial electrical stimulation

2016 ◽  
Author(s):  
Jacek P. Dmochowski ◽  
Laurent Koessler ◽  
Anthony M. Norcia ◽  
Marom Bikson ◽  
Lucas C. Parra
Keyword(s):  
Electrical Stimulation ◽  
Source Localization ◽  
Brain Stimulation ◽  
Closed Form Expression ◽  
Transcranial Electrical Stimulation ◽  
Stimulation Parameters ◽  
Theoretical Predictions ◽  
Brain And Behavior ◽  
Eeg Recordings ◽  
And Behavior

AbstractTo demonstrate causal relationships between brain and behavior, investigators would like to guide brain stimulation using measurements of neural activity. Particularly promising in this context are electroen-cephalography (EEG) and transcranial electrical stimulation (TES), as they are linked by a reciprocity principle which, despite being known for decades, has not led to a formalism for relating EEG recordings to optimal stimulation parameters. Here we derive a closed-form expression for the TES configuration that optimally stimulates (i.e., targets) the sources of recorded EEG, without making assumptions about source location or distribution. We also derive a duality between TES targeting and EEG source localization, and demonstrate that in cases where source localization fails, so does the proposed targeting. Numerical simulations with realistic head models confirm these theoretical predictions and quantify the achieved stimulation in terms of focality and intensity. We show that constraining the stimulation currents automatically selects optimal montages that involve only a few (4-7) electrodes, with only incremental loss in performance. The proposed technique allows brain scientists and clinicians to rationally target the sources of observed EEG and thus overcomes a major obstacle to the realization of individualized or closed-loop brain stimulation.

scholarly journals An Investigation of the Effect of Retraining Courses on the Knowledge, Attitude and Performance of Health Workers in the Field of Malaria

2021 ◽  
Vol 15 (6) ◽  
pp. 1598-1601
Author(s):  
Roghaye Ershad Sarabi ◽  
Rafigh Dehvari Mohammadi ◽  
Aziollah Arbabisarjou
Keyword(s):  
Health Center ◽  
Health Workers ◽  
Demographic Data ◽  
Knowledge Score ◽  
Before And After ◽  
The Face ◽  
Level Of Knowledge ◽  
And Performance ◽  
And Behavior ◽  
The Impact

Background: Malaria is considered one of the most important parasitic diseases in Iran. With regard to malaria, Sistan and Baluchestan province ranks first among the country's provinces. Aim: To investigate the impact of education on malaria knowledge, attitude and behavior among health workers working in Saravan city health center. Methods: The present study is a semi-experimental study of before and after clinical trial type that was performed on 73 health workers in Saravan city. A researcher-made questionnaire was used to collect the required data. It consisted of two parts: the first part was dedicated to demographic data and the second part was about the knowledge, attitude and performance of health workers regarding malaria. The face and content validity of the questionnaire was confirmed by an expert panel. The reliability of the questionnaire was calculated using Cronbach's alpha coefficient (α=0.85). Before the start of the training, the questionnaires were given to the health workers. The trainings were presented in 49 one-hour sessions by the experts of the headquarters of Saravan Health Center in Behvarzi Center using lectures and pamphlets. One month after the training, the same questionnaires were filled in by health workers. Results: The results showed that the mean scores of health workers in the areas of knowledge, attitude and performance increased significantly after the workshop (p=0.001) so that the participants' knowledge score increased from 26.06 to 56.7. In terms of attitude, their score increased from 7.2 to 17.7, and in terms of performance, participants' score increased from 13 to 32. Conclusions: The findings revealed that the implementation of educational programs in the field of malaria can increase the level of knowledge, attitude and performance of the community regarding the preventive behaviors of malaria. Therefore, health system officials are recommended to work toward the amelioration of the knowledge, attitude and performance of the health workers. Keywords: knowledge, attitude, performance, health workers, malaria, retrainin

scholarly journals Effects of Transcranial Electrical Stimulation on Human Auditory Processing and Behavior—A Review

2020 ◽  
Vol 10 (8) ◽  
pp. 531
Author(s):  
Yao Wang ◽  
Limeng Shi ◽  
Gaoyuan Dong ◽  
Zuoying Zhang ◽  
Ruijuan Chen
Keyword(s):  
Electrical Stimulation ◽  
Auditory Processing ◽  
Transcranial Electrical Stimulation ◽  
Weak Current ◽  
Auditory Pattern ◽  
Nerve Activity ◽  
Neural Processes ◽  
And Behavior ◽  
Auditory Processes ◽  
Electrophysiological Effects

Transcranial electrical stimulation (tES) can adjust the membrane potential by applying a weak current on the scalp to change the related nerve activity. In recent years, tES has proven its value in studying the neural processes involved in human behavior. The study of central auditory processes focuses on the analysis of behavioral phenomena, including sound localization, auditory pattern recognition, and auditory discrimination. To our knowledge, studies on the application of tES in the field of hearing and the electrophysiological effects are limited. Therefore, we reviewed the neuromodulatory effect of tES on auditory processing, behavior, and cognitive function and have summarized the physiological effects of tES on the auditory cortex.

scholarly journals fMRI and Transcranial Electrical Stimulation (tES): A systematic review of parameter space and outcomes

2020 ◽  
Author(s):  
Peyman Ghobadi-Azbari ◽  
Asif Jamil ◽  
Fatemeh Yavari ◽  
Zeinab Esmaeilpour ◽  
Nastaran Malmir ◽  
...  
Keyword(s):  
Systematic Review ◽  
Electrical Stimulation ◽  
Parameter Space ◽  
Brain Activity ◽  
Random Noise ◽  
Brain Regions ◽  
Transcranial Electrical Stimulation ◽  
Future Studies ◽  
Non Invasive ◽  
And Behavior

AbstractThe combination of non-invasive brain stimulation interventions with human brain mapping methods have supported research beyond correlational associations between brain activity and behavior. Functional MRI (fMRI) partnered with transcranial electrical stimulation (tES) methods, i.e., transcranial direct current (tDCS), transcranial alternating current (tACS), and transcranial random noise (tRNS) stimulation, explore the neuromodulatory effects of tES in the targeted brain regions and their interconnected networks and provide opportunities for individualized interventions. Advances in the field of tES-fMRI can be hampered by the methodological variability between studies that confounds comparability/replicability. In order to explore variability in the tES-fMRI methodological parameter space (MPS), we conducted a systematic review of 222 tES-fMRI experiments (181 tDCS, 39 tACS and 2 tRNS) published before February 1, 2019, and suggested a framework to systematically report main elements of MPS across studies. We have organized main findings in terms of fMRI modulation by tES. tES modulates activation and connectivity beyond the stimulated areas particularly with prefrontal stimulation. There were no two studies with the same MPS to replicate findings. We discuss how to harmonize the MPS to promote replication in future studies.

scholarly journals Transcranial electrical stimulation motor-evoked potentials in a spinal cord ischaemia rabbit model

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Yucheng Lu ◽  
Baotao Lv ◽  
Qimin Song
Keyword(s):  
Spinal Cord ◽  
Electrical Stimulation ◽  
Evoked Potentials ◽  
Motor Evoked Potentials ◽  
Rabbit Model ◽  
Transcranial Electrical Stimulation ◽  
Spinal Cord Ischaemia ◽  
Ischaemic Damage ◽  
Vascular Ligation ◽  
Before And After

Abstract Background Spinal cord ischaemia animal models were established by selective ligation of the lumbar artery in a craniocaudal direction between the renal artery and the aortic bifurcation. Transcranial electrical stimulation motor-evoked potentials were measured to enable their use in future studies on spinal cord ischaemia protection. Methods Thirty-three New Zealand rabbits were randomly divided into 6 groups. Transcranial electrical stimulation motor-evoked potentials were recorded before vascular ligation, 30 min after vascular ligation, and 2 days after vascular ligation. Motor functions were assessed after surgery and 2 days after vascular ligation. The specimens were taken 2 days after ligation for histopathologic observation. Results With increased numbers of ligations, a transient extension of the latency became clear, but there were no significant differences in the statistical analysis. Analysis of variance after ligation at the same time in each group and t tests before and after ligation (P > 0.05) were not significant. One or 2 ligations did not cause spinal cord ischaemic damage. There were no significant differences before and after ligation for the amplitude (P > 0.05). With increased numbers of ligations, the amplitude before and after ligation was gradually reduced in the 3–5 ligation groups (P < 0.05). Conclusions Ligation of segmental spinal cord vessels on 1 or 2 levels did not cause ischaemic damage. Spinal cord ischaemia was observed after 3, 4, or 5 ligations. The amplitude was more sensitive to spinal cord ischaemia than latency. Spinal cord function can be predicted by early changes in the amplitude.

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