scholarly journals Risk factors for orthodontic mini-implants in skeletal anchorage biological stability: a systematic literature review and meta-analysis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
María Dolores Casaña-Ruiz ◽  
Carlos Bellot-Arcís ◽  
Vanessa Paredes-Gallardo ◽  
Verónica García-Sanz ◽  
José Manuel Almerich-Silla ◽  
...  
Gerontology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Akshaya Srikanth Bhagavathula ◽  
Eyob Alemayehu Gebreyohannes ◽  
Daniela Fialova

<b><i>Background and Aim:</i></b> Polypharmacy and potentially inappropriate medication (PIM) use in older populations (65+ years) have not yet been investigated by meta-analyses in developing countries. This systematic literature review and meta-analysis aimed to investigate the prevalence of polypharmacy and PIM use and major risk factors associated with PIM prescribing in older adults in Ethiopia. <b><i>Methods:</i></b> We searched PubMed/MEDLINE, Scopus, Embase, and Google Scholar databases to identify relevant studies published between January 1990 and October 2020. Observational studies reporting the prevalence and association of risk factors with polypharmacy and PIM use in the older population were meta-analyzed. A multilevel meta-analysis was conducted to pool the prevalence estimates, and the risk of PIM use was reported as a relative risk (RR) with a 95% confidence interval (CI). <b><i>Results:</i></b> We identified by systematic literature review 404 articles. Of those, 8 studies fulfilled inclusion criteria, comprising a total sample of 2,608 participants. The overall prevalence of polypharmacy and PIM use pooled by meta-analysis in the Ethiopian older population was 33 and 37%, respectively. The risk factors of PIM use were analyzed in the meta-analysis (particularly polymorbidity, polypharmacy, gender, and older age), and only older age of 65+ (RR: 1.71, 95% CI: 1.16–2.51) was significantly associated with PIM use. <b><i>Conclusion:</i></b> This first meta-analysis from a developing country revealed a high prevalence of polypharmacy and PIM use in the Ethiopian older population. There was no awareness about the risk of PIMs in patients with polypharmacy and polymorbidity, and older age significantly predicted PIM use. Interventions ensuring rational geriatric pharmacotherapy are essential in developing countries in order to reduce the expected burden of PIM-related geriatric morbidity, higher costs, and mortality.


2020 ◽  
Vol 185 ◽  
pp. 105176
Author(s):  
Arlan Araujo Rodrigues ◽  
Sara Silva Reis ◽  
Milenne Lima de Sousa ◽  
Elinalva da Silva Moraes ◽  
João Luis Garcia ◽  
...  

2020 ◽  
Vol 49 (6) ◽  
pp. 770-778 ◽  
Author(s):  
R. Gómez-Barrachina ◽  
J.M. Montiel-Company ◽  
V. García-Sanz ◽  
J.M. Almerich-Silla ◽  
V. Paredes-Gallardo ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Vijayalaxmi V. Mogasale ◽  
Enusa Ramani ◽  
Vittal Mogasale ◽  
Ju Yeon Park ◽  
Thomas F. Wierzba

Background. Unsafe water is a well-known risk for typhoid fever, but a pooled estimate of the population-level risk of typhoid fever resulting from exposure to unsafe water has not been quantified. An accurate estimation of the risk from unsafe water will be useful in demarcating high-risk populations, modeling typhoid disease burden, and targeting prevention and control activities. Methods. We conducted a systematic literature review and meta-analysis of observational studies that measured the risk of typhoid fever associated with drinking unimproved water as per WHO-UNICEF’s definition or drinking microbiologically unsafe water. The mean value for the pooled odds ratio from case-control studies was calculated using a random effects model. In addition to unimproved water and unsafe water, we also listed categories of other risk factors from the selected studies. Results. The search of published studies from January 1, 1990, to December 31, 2013 in PubMed, Embase, and World Health Organization databases provided 779 publications, of which 12 case-control studies presented the odds of having typhoid fever for those exposed to unimproved or unsafe versus improved drinking water sources. The odds of typhoid fever among those exposed to unimproved or unsafe water ranged from 1.06 to 9.26 with case weighted mean of 2.44 (95% CI: 1.65–3.59). Besides water-related risk, the studies also identified other risk factors related to socioeconomic aspects, type of food consumption, knowledge and awareness about typhoid fever, and hygiene practices. Conclusions. In this meta-analysis, we have quantified the pooled risk of typhoid fever among people exposed to unimproved or unsafe water which is almost two and a half times more than people who were not exposed to unimproved or unsafe water. However, caution should be exercised in applying the findings from this study in modeling typhoid fever disease burden at country, regional, and global levels as improved water does not always equate to safe water.


2020 ◽  
Vol 81 (4) ◽  
pp. 647-679 ◽  
Author(s):  
Rama Jayaraj ◽  
Chellan Kumarasamy ◽  
Sameep S. Shetty ◽  
Ravishankar Ram M ◽  
Peter Shaw

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Bénédicte Vos ◽  
Dorie Noll ◽  
Marie Pigeon ◽  
Marlene Bagatto ◽  
Elizabeth M. Fitzpatrick

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