scholarly journals Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Anne Schienle ◽  
Isabella Unger

AbstractPlacebos, that are administered with deception, can reduce stress and increase relaxation. The present study investigated an open-label placebo (OLP) to improve the effects of Progressive Muscle Relaxation (PMR) training. A total of 160 psychology students were randomly assigned to a 14-day PMR course with or without daily OLP treatment. The placebo was administered along with an explanation of placebo effects and the verbal suggestion that the OLP activates the body’s natural relaxation response. The relaxation instructions for home practice were delivered via a smartphone app, which was also used for the evaluation of the exercises. The participants of the OLP group completed more PMR exercises (M = 9.75) than the group without a placebo (M = 8.15). The two groups did not differ in reported exercise-related changes in relaxation level. On average, the OLP group rated the effects of the placebo as very low and was characterized by a higher drop-out rate compared to the group without OLP. Some participants experienced the OLP as negative. In conclusion, factors that influence the acceptance of OLP treatment require further investigation.

2021 ◽  
Vol 12 (4) ◽  
pp. 1
Author(s):  
Hanan Mohamed Soliman ◽  
Ahmed Eltantawy ◽  
Rania El-Kurdy

Background and objective: This study was conducted to examine the effect of progressive muscle relaxation training (PMRT) in combination with antiemetic drugs on chemotherapy-associated nausea, vomiting and anxiety in breast cancer women receiving chemotherapy.Methods: A randomized controlled trial design was conducted on 74 patients divided into control (n = 37) and PMRT group (n = 37). The study was conducted at Oncology Center affiliated to Mansoura University, Egypt. The intervention included daily PMRT practice for seven days two hours before chemotherapy. The patients exercised in the oncology unit with the researcher, and individually applied the exercises at home. The data was collected using Rhodes index of nausea-vomiting and retching used daily after chemotherapy for seven days and Zung self-rating anxiety scale used before chemotherapy and at the seventh and 14th days after chemotherapy.Results: A significant decrease in the frequency, severity, and duration of vomiting, nausea, retching and anxiety in PMRT group than in the control group (p < .0001). Conclusions: Progressive muscle relaxation combined with antiemetics was effective in reducing vomiting, nausea, and retching, as well as improving anxiety level induced by chemotherapy.


2020 ◽  
Vol 60 (10) ◽  
pp. 2232-2246
Author(s):  
Mia T. Minen ◽  
Samrachana Adhikari ◽  
Jane Padikkala ◽  
Sumaiya Tasneem ◽  
Ashley Bagheri ◽  
...  

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