scholarly journals A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Blanca Marin Bosch ◽  
Aurélien Bringard ◽  
Maria G. Logrieco ◽  
Estelle Lauer ◽  
Nathalie Imobersteg ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Neurotrophic Factor ◽  
Acute Exercise ◽  
Memory Performance ◽  
Brain Derived Neurotrophic Factor ◽  
Moderate Intensity ◽  
Single Session ◽  
Moderate Intensity Exercise ◽  
Memory Representations

AbstractRegular physical exercise enhances memory functions, synaptic plasticity in the hippocampus, and brain derived neurotrophic factor (BDNF) levels. Likewise, short periods of exercise, or acute exercise, benefit hippocampal plasticity in rodents, via increased endocannabinoids (especially anandamide, AEA) and BDNF release. Yet, it remains unknown whether acute exercise has similar effects on BDNF and AEA levels in humans, with parallel influences on memory performance. Here we combined blood biomarkers, behavioral, and fMRI measurements to assess the impact of a single session of physical exercise on associative memory and underlying neurophysiological mechanisms in healthy male volunteers. For each participant, memory was tested after three conditions: rest, moderate or high intensity exercise. A long-term memory retest took place 3 months later. At both test and retest, memory performance after moderate intensity exercise was increased compared to rest. Memory after moderate intensity exercise correlated with exercise-induced increases in both AEA and BNDF levels: while AEA was associated with hippocampal activity during memory recall, BDNF enhanced hippocampal memory representations and long-term performance. These findings demonstrate that acute moderate intensity exercise benefits consolidation of hippocampal memory representations, and that endocannabinoids and BNDF signaling may contribute to the synergic modulation of underlying neural plasticity mechanisms.

scholarly journals Acute Exercise Stress Reveals Cerebrovascular Benefits Associated with Moderate Gains in Cardiorespiratory Fitness

2014 ◽  
Vol 34 (12) ◽  
pp. 1873-1876 ◽  
Author(s):  
Julien V Brugniaux ◽  
Christopher J Marley ◽  
Danielle A Hodson ◽  
Karl J New ◽  
Damian M Bailey
Keyword(s):  
Cardiorespiratory Fitness ◽  
Acute Exercise ◽  
Cerebral Oxygenation ◽  
Exercise Stress ◽  
Moderate Intensity ◽  
Moderate Increase ◽  
Moderate Intensity Exercise ◽  
Prefrontal Cortical ◽  
Hb Concentration

Elevated cardiorespiratory fitness improves resting cerebral perfusion, although to what extent this is further amplified during acute exposure to exercise stress and the corresponding implications for cerebral oxygenation remain unknown. To examine this, we recruited 12 moderately active and 12 sedentary healthy males. Middle cerebral artery blood velocity (MCAv) and prefrontal cortical oxyhemoglobin (cO2Hb) concentration were monitored continuously at rest and throughout an incremental cycling test to exhaustion. Despite a subtle elevation in the maximal oxygen uptake (active: 52 ± 9 ml/kg per minute versus sedentary: 33 ± 5 ml/kg per minute, P < 0.05), resting MCAv was not different between groups. However, more marked increases in both MCAv (+28 ± 13% versus +18 ± 6%, P < 0.05) and cO2Hb (+5 ±4% versus −2 ± 3%, P < 0.05) were observed in the active group during the transition from low- to moderate-intensity exercise. Collectively, these findings indicate that the long-term benefits associated with moderate increase in physical activity are not observed in the resting state and only become apparent when the cerebrovasculature is challenged by acute exertional stress. This has important clinical implications when assessing the true extent of cerebrovascular adaptation.

scholarly journals Acute physical exercise improves memory consolidation in humans via BDNF and endocannabinoid signaling

2017 ◽  
Author(s):  
Blanca Marin Bosch ◽  
Aurélien Bringard ◽  
Maria Grazia Logrieco ◽  
Estelle Lauer ◽  
Nathalie Imobersteg ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Acute Exercise ◽  
Memory Performance ◽  
Long Term Memory ◽  
Hippocampal Activity ◽  
High Exercise Intensity ◽  
Acute Physical Exercise ◽  
Term Performance ◽  
The Impact

AbstractRegular physical exercise enhances memory functions and neurogenesis in the hippocampus, an effect partially mediated by BDNF (Brain Derived Neurotrophic Factor). Acute exercise promotes the release of endocannabinoids (especially anandamide, AEA), which enhance BDNF release and improve hippocampal plasticity in rodents. How acute exercise affects BDNF and AEA levels and influences memory performance in humans remains to date unknown. Here we combined blood biomarkers, behavioral and fMRI measurements to assess the impact of acute physical exercise on associative memory and underlying neurophysiological mechanisms. For each participant, memory was tested after three conditions: rest, moderate or high exercise intensity. A long-term memory retest took place 3 months later. At both test and retest, memory performance increased after moderate but not high intensity exercise or rest. We also show that memory benefited from exercise-related increases in both AEA and BNDF levels: AEA boosted hippocampal activity during memory recall, while BDNF enhanced hippocampal memory representations and long-term performance.

Effects of Acute Exercise on Memory Performance in Middle-Aged and Older Adults

2020 ◽  
pp. 1-8
Author(s):  
Jennifer L. Etnier ◽  
Jarod C. Vance ◽  
Aiko Ueno
Keyword(s):  
Older Adults ◽  
Acute Exercise ◽  
Memory Performance ◽  
Moderate Intensity ◽  
Long Term Memory ◽  
Middle Aged ◽  
Moderate Intensity Exercise ◽  
Auditory Learning ◽  
Verbal Test ◽  
Within Subjects

Numerous studies show that exercise benefits memory and some show that acute exercise prior to encoding has larger benefits than exercise after encoding. This study was designed to investigate the effects of acute exercise on memory in middle-aged and older adults (Mage = 64.71 years) and to explore the influence of the timing of the exercise on these effects. Using a within-subjects design, moderate-intensity exercise (20 min) was either not performed (control), performed before the task (exercise prior), or performed after the task (exercise post). Memory was assessed using the Rey Auditory Learning Verbal Test. For short- and long-term memory and learning, significantly more words were remembered in the exercise-prior condition than the others. For 24-hr recall, participants remembered significantly more words in the exercise-prior condition than exercise post, which was better than control. Exercise benefits memory for healthy middle-aged and older adults, with the greatest benefits when performed prior to encoding.

scholarly journals No Change in Brain-Derived Neurotrophic Factor Levels Following a Single Session of Light to-Moderate Intensity Walk in Chronic Stroke Patients

2017 ◽  
Vol 05 (02) ◽  
Author(s):  
Mariana Lacerda e Silva ◽  
Viviane Aparecida Carvalho de Morais ◽  
Renata Maria Silva Santos ◽  
Natalia Pessoa Rocha ◽  
Paulo Pereira Christo ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Chronic Stroke ◽  
Moderate Intensity ◽  
Single Session ◽  
Stroke Patients

scholarly journals Acute increases in brain-derived neurotrophic factor following high or moderate-intensity exercise is accompanied with better cognition performance in obese adults

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Daniela Sayuri Inoue ◽  
Paula Alves Monteiro ◽  
José Gerosa-Neto ◽  
Priscilla Rodrigues Santana ◽  
Fernando Pierin Peres ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Obese Adults

scholarly journals The Effects of Acute Exercise on Memory and Brain-Derived Neurotrophic Factor (BDNF)

2016 ◽  
Vol 38 (4) ◽  
pp. 331-340 ◽  
Author(s):  
Jennifer L. Etnier ◽  
Laurie Wideman ◽  
Jeffrey D. Labban ◽  
Aaron T. Piepmeier ◽  
Daniel M. Pendleton ◽  
...  
Keyword(s):  
Exercise Intensity ◽  
Neurotrophic Factor ◽  
Acute Exercise ◽  
Short Term Memory ◽  
Verbal Learning ◽  
Brain Derived Neurotrophic Factor ◽  
Future Research ◽  
Long Term Memory ◽  
Term Memory

Acute exercise benefits cognition, and some evidence suggests that brain-derived neurotrophic factor (BDNF) plays a role in this effect. The purpose of this study was to explore the dose–response relationship between exercise intensity, memory, and BDNF. Young adults completed 3 exercise sessions at different intensities relative to ventilator threshold (Vt) (VO2max, Vt – 20%, Vt + 20%). For each session, participants exercised for approximately 30 min. Following exercise, they performed the Rey Auditory Verbal Learning Test (RAVLT) to assess short-term memory, learning, and long-term memory recall. Twenty-four hours later, they completed the RAVLT recognition trial, which provided another measure of long-term memory. Blood was drawn before exercise, immediately postexercise, and after the 30-min recall test. Results indicated that long-term memory as assessed after the 24-hr delay differed as a function of exercise intensity with the largest benefits observed following maximal intensity exercise. BDNF data showed a significant increase in response to exercise; however, there were no differences relative to exercise intensity and there were no significant associations between BDNF and memory. Future research is warranted so that we can better understand how to use exercise to benefit cognitive performance.

scholarly journals Shedding Light on the Effects of Moderate Acute Exercise on Working Memory Performance in Healthy Older Adults: An fNIRS Study

2020 ◽  
Vol 10 (11) ◽  
pp. 813 ◽  
Author(s):  
Katharina Stute ◽  
Nicole Hudl ◽  
Robert Stojan ◽  
Claudia Voelcker-Rehage
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Executive Functions ◽  
Acute Exercise ◽  
Memory Performance ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Post Exercise ◽  
Healthy Older Adults ◽  
Beneficial Effects

Numerous studies have reported the beneficial effects of acute exercise on executive functions. Less is known, however, about the effects of exercise on working memory as one subcomponent of executive functions and about its effects on older adults. We investigated the effects of acute moderate-intensity exercise on working memory performance, the respective cortical hemodynamic activation patterns, and the development and persistence of such effects in healthy older adults. Forty-four participants (M: 69.18 years ± 3.92; 21 females) performed a letter 2-back task before and at three time points after (post 15 min, post 30 min, and post 45 min) either listening to an audiobook or exercising (15 min; 50% VO2-peak). Functional near-infrared spectroscopy (fNIRS) was used to assess cortical hemodynamic activation and brain-behavior correlations in the fronto-parietal working memory network. Overall, we found no group differences for working memory performance. However, only within the experimental group, 2-back performance was enhanced 15 min and 45 min post-exercise. Furthermore, 15 min post-exercise frontal activation predicted working memory performance, regardless of group. In sum, our results indicate slight beneficial effects of acute moderate-intensity exercise on working memory performance in healthy older adults. Findings are discussed in light of the cognitive aging process and moderators affecting the exercise-cognition relationship.

A single session of moderate intensity walking increases brain-derived neurotrophic factor (BDNF) in the chronic post-stroke patients

2017 ◽  
Vol 25 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Viviane Aparecida Carvalho de Morais ◽  
Marina Ferreira da Silva Tourino ◽  
Ana Carolina de Souza Almeida ◽  
Thaís Bueno Dias Albuquerque ◽  
Roberta Castro Linhares ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Moderate Intensity ◽  
Single Session ◽  
Stroke Patients ◽  
Post Stroke

scholarly journals The effects of different protocols of physical exercise and rest on long-term memory

2019 ◽  
Author(s):  
Wesley Pyke ◽  
Fadi Ifram ◽  
Laura Coventry ◽  
Yee Sung ◽  
Isabelle Champion ◽  
...  
Keyword(s):  
Physical Exercise ◽  
High Intensity ◽  
Interval Training ◽  
Moderate Intensity ◽  
Long Term Memory ◽  
High Intensity Interval Training ◽  
Moderate Intensity Exercise ◽  
Term Memory ◽  
High Intensity Interval

Objectives Many studies have looked at the effects of physical exercise on long-term memory. However, to date, no study has compared the effect of different intensities and protocols of physical exercise and different rest conditions on long-term memory. Methods In three studies (N=59) we measured the extent that physical exercise (in its varying intensities) and wakeful rest (active-rest; in which participants were cognitively engaged while seated and passive-rest; no cognitive engagement while seated) could influence long-term memory. Across all three studies, nearly identical procedures were employed, using the same old/new recognition memory test in order to establish the most effective protocol for cognitive enhancement. In Study 1, the effects of continuous moderate intensity exercise, uninterrupted wakeful rest (passive) and rest with an engagement task (active) were explored. In Study 2, continuous moderate intensity exercise was compared to high-intensity interval training (HIIT) and passive rest. Study 3 observed the effects of low-, moderate- and high-intensity continuous exercise. Results Across the three studies moderate intensity exercise had the greatest positive impact on memory performance. Passive rest was more effective than active rest, however, less than high-intensity interval-training (HIIT). Conclusion Our findings suggest that it is not necessary to physically overexert oneself in order to achieve observable improvements to long-term memory. By also investigating uninterrupted wakeful rest, it reaffirmed the importance of the consolidation period for the formation of long-term memories.

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