scholarly journals An Amniotic Fluid Index ≤5 cm Within 7 Days of Delivery in the Third Trimester Is Not Associated with Decreasing Umbilical Arterial pH and Base Excess

2004 ◽  
Vol 24 (2) ◽  
pp. 72-76 ◽  
Author(s):  
Rita W Driggers ◽  
Cynthia J Holcroft ◽  
Karin J Blakemore ◽  
Ernest M Graham
Keyword(s):  
Amniotic Fluid ◽  
Base Excess ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
The Third ◽  
Arterial Ph ◽  
Umbilical Arterial Ph

Effects of Air Pollution in Amniotic Fluid Index in the Third Trimester of Pregnancy

2014 ◽  
Vol 2014 (1) ◽  
pp. 2626
Author(s):  
Mariana Azevedo Carvalho ◽  
Lisandra Stein Bernardes ◽  
karen Hettfleisch ◽  
Luciana D M Pastro ◽  
Silvia R.D.M Saldiva* ◽  
...  
Keyword(s):  
Air Pollution ◽  
Amniotic Fluid ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
The Third

scholarly journals Maternal (oral) hydration increases amniotic fluid volume

2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Aneela Umber
Keyword(s):  
Specific Gravity ◽  
Amniotic Fluid ◽  
Fluid Volume ◽  
Urine Specific Gravity ◽  
P Value ◽  
Percentage Increase ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
Oral Hydration ◽  
Amniotic Fluid Volume

Objective:To determine the effect of maternal (oral) hydration on amniotic fluid volume in patients with third trimester oligohydramnios. Design: Interventional study. Place and Duration of Study: Department of Obs & Gynae Unit III, Sir Ganga Ram Hospital, Lahore from May 2002 to October 2002. Patients and Methods: Twenty five women with third trimester oligohydramnios (AFI ?5.0cm) and twenty five controls with normal amniotic fluid volume (AFI 8-24 cm) were prospectively recruited for this study. Maternal urine specific gravity and amniotic fluid index were determined before and after maternal hydration by asking them to drink 2 L of water in 2-4 hours before repeat amniotic fluid index and recorded on printed proformas. Results: Hydration increased amniotic fluid volume in women with oligohydramnios (mean change in amniotic fluid index 4.3 cm, 95% confidence interval 4.02 to 5.06; P value <0.001); as well as in women with normal fluid volume (mean change in Amniotic fluid index 2.7 cm, 95% confidence interval 2.23 to 3.21; P value <0.01). However, percentage increase in mean AFI was 58.6% in the oligohydramnios group, which was significantly greater (P value <0.05) than the percentage increase of 28.4% in control group. Hydration was associated with decrease in urine specific gravity in both groups. Conclusion: Maternal (oral) hydration increases AFV in women with oligohydramnios as well as in women with normal AFV and may be beneficial in the management of oligohydramnios.

scholarly journals Correlation study between increased fetal movement during the third trimester and neonatal outcome

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Cuiqin Huang ◽  
Wei Han ◽  
Yajing Fan
Keyword(s):  
Amniotic Fluid ◽  
Pregnant Women ◽  
Gestational Age ◽  
Neonatal Outcome ◽  
Stress Test ◽  
Neonatal Outcomes ◽  
Control Group ◽  
Third Trimester ◽  
The Third ◽  
Fetal Movements

Abstract Background We aimed to analyze the correlation between increased fetal movements in the third trimester and neonatal outcomes. Methods We enrolled pregnant women (n = 219) who reported increased/excessive fetal movements in the third trimester in our hospital. A control group of healthy women (n = 278) who had undergone regular childbirth and delivery in our hospital during the same period and did not report abnormal fetal movements were also recruited. All pregnant women underwent fetal non-stress test. We analyzed the neonatal weight, appearance, pulse, grimace, activity, and respiration score, degrees of amniotic fluid contamination, amniotic fluid volume, conditions of umbilical cord around the neck and cord length, and incidence of small for gestational age. In addition, the incidence of preterm delivery, cesarean section rate, postpartum hemorrhage, and other postpartum complications were also analyzed. We then analyzed the correlation between increased/excessive fetal activity and neonatal outcomes. Results Women with complaints of increased/excessive fetal movements exhibited increased fetal movements mainly around 31 and 39 weeks of gestation. Several pregnancy variables, including number of previous delivery, gestational age (less than 34 weeks and more than 37 weeks) and vaginal birth rate, were associated with increased/excessive fetal movements. In addition, women who reported increased/excessive fetal movements had higher odds of large for gestational age (LGA), particularly those with gestational age over 37 weeks. Conclusion Increased/excessive fetal movements may be used to predict adverse neonatal outcome such as LGA.

scholarly journals Comparison of the amniotic fluid and fetal urine peptidome for biomarker discovery in renal developmental disease

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Camille Fédou ◽  
Benjamin Breuil ◽  
Igor Golovko ◽  
Stéphane Decramer ◽  
Pedro Magalhães ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Biomarker Discovery ◽  
Posterior Urethral Valves ◽  
Proof Of Concept ◽  
Renal Survival ◽  
Third Trimester ◽  
Urethral Valves ◽  
Endogenous Peptides ◽  
The Third ◽  
Fetal Urine

AbstractProduction of amniotic fluid (AF) is view as predominately driven by excretion of fetal urine (FU). However, the origin of AF peptides, often considered as potential biomarkers of developmental diseases, has never been investigated. Here, we evaluated the FU origin of AF peptides and if the AF peptide content can be used as a surrogate of FU. The abundance of endogenous peptides was analyzed by capillary electrophoresis coupled to mass spectrometry in 216 AF and 64 FU samples. A total of 2668 and 3257 peptides was found in AF and FU respectively. The AF peptidome largely overlapped with the FU peptidome, ranging from 54% in the second pregnancy trimester to 65% in the third trimester. Examination of a subset of 16 paired AF and FU samples revealed that 67 peptides displayed a significant positively correlated abundance in AF and FU, strongly suggesting that their presence in AF was directly associated to FU excretion. As proof-of-concept we showed that measuring the AF abundance of these 67 peptides of FU origin allowed prediction of postnatal renal survival in fetuses with posterior urethral valves. These results demonstrate that the AF peptidome can be considered as a good surrogate of the FU peptidome.

Pharmacokinetics of ethanol and its metabolite, acetaldehyde, and fetolethality in the third-trimester pregnant guinea pig for oral administration of acute, multiple-dose ethanol

1986 ◽  
Vol 64 (8) ◽  
pp. 1060-1067 ◽  
Author(s):  
David W. Clarke ◽  
Nancy A. E. Steenaart ◽  
Christopher J. Slack ◽  
James F. Brien
Keyword(s):  
Guinea Pig ◽  
Amniotic Fluid ◽  
Ethanol Concentration ◽  
Fetal Brain ◽  
Maternal Blood ◽  
Time Interval ◽  
Gas Liquid Chromatography ◽  
Fetal Blood ◽  
Third Trimester ◽  
The Third

The pharmacokinetics of ethanol and its metabolite, acetaldehyde, were determined in the third-trimester pregnant guinea pig (56–59 days gestation) for oral intubation of four doses of 1 g ethanol/kg maternal body weight, administered at 1-h intervals. Animals (n = 4–7) were sacrificed at each of selected times during the 26-h study. Ethanol and acetaldehyde concentrations were determined by headspace gas-liquid chromatography. The maternal and fetal blood ethanol concentration–time curves were virtually superimposable, which indicated unimpeded bidirectional placental transfer of ethanol in the matemal–fetal unit. The blood and brain ethanol concentrations were similar in each of the maternal and fetal compartments during the study, which indicated rapid equilibrium distribution of ethanol. There was accumulation of ethanol in the amniotic fluid resulting in higher ethanol concentration compared with maternal and fetal blood during the elimination phase, which indicated that the amniotic fluid may serve as a reservoir for ethanol in utero. Acetaldehyde was measurable in all the biological fluids and tissues at concentrations that were at least 1000-fold less than the respective ethanol concentrations and were variable. There was ethanol-induced fetolethality that was delayed and variable among animals, and was 55% at 23 h. At this time interval, the ethanol concentrations in maternal blood and brain, fetal brain, and amniotic fluid were 35- to 53-fold greater and the acetaldehyde concentrations in maternal blood and fetal brain were four- to five-fold higher in the animals with dead fetuses compared with the guinea pigs with live litters. These data indicated that decreased ethanol elimination from the maternal–fetal unit was related temporally to the fetolethality.

Presence of CRH-binding protein in amniotic fluid and in umbilical cord plasma

1991 ◽  
Vol 125 (2) ◽  
pp. 165-169 ◽  
Author(s):  
Toshihiro Suda ◽  
Mitsutoshi Iwashita ◽  
Takashi Sumitomo ◽  
Yoriko Nakano ◽  
Fumiko Tozawa ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Umbilical Cord ◽  
Peripheral Blood ◽  
Binding Protein ◽  
Normal Subjects ◽  
Normal Adult ◽  
Second Trimester ◽  
Third Trimester ◽  
The Third ◽  
Cord Plasma

Abstract. CRH-binding protein was present in the amniotic fluid and in the umbilical cord plasma after 15 weeks and 24 weeks of pregnancy, respectively. The size of the CRH-binding protein was similar to that in the peripheral blood from normal subjects. The level of the binding of CRH-binding protein in the umbilical cord plasma during the third trimester of pregnancy was also similar to that in the peripheral blood of neonates and normal adult subjects. The binding of CRH-binding protein was temporarily decreased at 40 weeks of pregnancy. These results indicate that fetal CRH-binding protein seems to be produced at least in the second trimester of pregnancy.

scholarly journals EFFECTS OF ORAL FLUIDS AND INTRAVENOUS FLUIDS IN THE IMPROVEMENT OF AMNIOTIC FLUID INDEX DURING THIRD TRIMESTER OF PREGNANCY

2021 ◽  
Vol 71 (1) ◽  
pp. 179-83
Author(s):  
Mehwish Malik ◽  
Samina Irshaad ◽  
Nadia Ahmed Bokhari ◽  
Wardah Ajaz Qazi ◽  
Asia Raza ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Gestational Age ◽  
Sampling Technique ◽  
Intravenous Fluids ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
Singleton Pregnancy ◽  
Oral Fluids ◽  
Group A ◽  
Group B

Objective: To assess the effects of oral fluids and intravenous fluids in terms of frequency of improving Amniotic Fluid Index during third trimester of pregnancy having oligohydramnios.Study Design: Comparative prospective survey. Place and Duration of Study: Obstetrics and Gynaecological Department of Fauji Foundation HospitalRawalpindi, from Apr 2018 to Oct 2018. Methodology: A total of 100 patients with singleton pregnancy (50 in each group) at gestational age of 28-37weeks and AFI of 5cm or less than 5cm were included. Non probability consecutive sampling technique wasused. Ethics approval from hospital ethical committee and research board was taken. Patients were randomizedinto 2 groups (50 patients each) by lottery method. Group A was instructed to drink 2 liters of water per day fora time period of seven days and patients in group B was given 2 liters of 5% D/W which was in addition to theirnormal fluids intake. Amniotic fluid index was measured pre hydration and post hydration in both groups. Datawas analyzed using SPSS-21. Results: Mean age of the patients was 33.62 ± 5.45 years and 34.70 ± 4.76 years for groups A and B respectively.In group A and group B mean gestational age was 34.28 ± 1.85 weeks vs 34.32 ± 1.82 weeks. In group A, 44 (88%)..............

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