Core-structure-inspired asymmetric addition reactions: enantioselective synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents

An overview of the asymmetric synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents (Efavirenz, DPC 961, DPC 963, DPC 083) and analogues was presented.

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ChemInform Abstract: Core-Structure-Inspired Asymmetric Addition Reactions: Enantioselective Synthesis of Dihydrobenzoxazinone- and Dihydroquinazolinone-Based anti-HIV Agents

ChemInform ◽

10.1002/chin.201550230 ◽

2015 ◽

Vol 46 (50) ◽

pp. no-no

Author(s):

Shen Li ◽

Jun-An Ma

Keyword(s):

Core Structure ◽

Enantioselective Synthesis ◽

Addition Reactions ◽

Asymmetric Addition ◽

Anti Hiv Agents ◽

Anti Hiv

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L-.beta.-(2S,4S)- and L-.alpha.-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships

Journal of Medicinal Chemistry ◽

10.1021/jm00057a001 ◽

1993 ◽

Vol 36 (5) ◽

pp. 519-528 ◽

Cited By ~ 65

Author(s):

Hea O. Kim ◽

Raymond F. Schinazi ◽

Kirupathevy Shanmuganathan ◽

Lak S. Jeong ◽

J. Warren Beach ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Structure Activity Relationships ◽

Structure Activity ◽

Anti Hiv Agents ◽

Anti Hiv

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ChemInform Abstract: Facile Asymmetric Synthesis of α-Amino Acids Employing Chiral Ligand Mediated Asymmetric Addition Reactions of Phenyllithium with Imines.

ChemInform ◽

10.1002/chin.200116193 ◽

2001 ◽

Vol 32 (16) ◽

pp. no-no

Author(s):

Masayoshi Hasegawa ◽

Daisuke Taniyama ◽

Kiyoshi Tomioka

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Addition Reactions ◽

Chiral Ligand ◽

Asymmetric Addition

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Asymmetric Addition Reactions of Grignard Reagents to Chiral Fluoral Hemiacetal: Asymmetric Synthesis of 1-Substituted-2,2,2-Trifluoroethylamines

Synlett ◽

10.1055/s-1997-1078 ◽

2000 ◽

Vol 12 (12) ◽

pp. 1381-1382 ◽

Cited By ~ 24

Author(s):

Akihiro Ishii ◽

Kimio Higashiyama ◽

Koichi Mikami

Keyword(s):

Asymmetric Synthesis ◽

Grignard Reagents ◽

Addition Reactions ◽

Asymmetric Addition

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Towards the Enantioselective Synthesis of anti-HIV Agents Litseaverticillols C and K from D-Glucose.

ChemInform ◽

10.1002/chin.200727155 ◽

2007 ◽

Vol 38 (27) ◽

Author(s):

Debendra K. Mohapatra ◽

Dhananjoy Mondal ◽

Mukund K. Gurjar

Keyword(s):

Enantioselective Synthesis ◽

Anti Hiv Agents ◽

Anti Hiv

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Asymmetric synthesis and biological evaluation of .beta.-L-(2R,5S)- and .alpha.-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents

Journal of Medicinal Chemistry ◽

10.1021/jm00054a001 ◽

1993 ◽

Vol 36 (2) ◽

pp. 181-195 ◽

Cited By ~ 97

Author(s):

Lak S. Jeong ◽

Raymond F. Schinazi ◽

J. Warren Beach ◽

Hea O. Kim ◽

Satyanarayana Nampalli ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Biological Evaluation ◽

Anti Hiv Agents ◽

Synthesis And Biological Evaluation ◽

Anti Hiv

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Facile Asymmetric Synthesis of α-Amino Acids Employing Chiral Ligand-Mediated Asymmetric Addition Reactions of Phenyllithium with Imines

Tetrahedron ◽

10.1016/s0040-4020(00)00860-7 ◽

2000 ◽

Vol 56 (52) ◽

pp. 10153-10158 ◽

Cited By ~ 39

Author(s):

Masayoshi Hasegawa ◽

Daisuke Taniyama ◽

Kiyoshi Tomioka

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Addition Reactions ◽

Chiral Ligand ◽

Asymmetric Addition

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ChemInform Abstract: Asymmetric Addition Reactions of Grignard Reagents to Chiral Fluoral Hemiacetal: Asymmetric Synthesis of 1-Substituted-2,2,2-trifluoroethylamines.

ChemInform ◽

10.1002/chin.199813085 ◽

2010 ◽

Vol 29 (13) ◽

pp. no-no

Author(s):

A. ISHII ◽

K. HIGASHIYAMA ◽

K. MIKAMI

Keyword(s):

Asymmetric Synthesis ◽

Grignard Reagents ◽

Addition Reactions ◽

Asymmetric Addition

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ChemInform Abstract: Asymmetric Synthesis and Biological Evaluation of β-L-(2R,5S)- and α-L-(2R,5R)-1,3-Oxathiolane-Pyrimidine and -Purine Nucleosides as Potential Anti-HIV Agents.

ChemInform ◽

10.1002/chin.199408291 ◽

2010 ◽

Vol 25 (8) ◽

pp. no-no

Author(s):

L. S. JEONG ◽

R. F. SCHINAZI ◽

J. W. BEACH ◽

H. O. KIM ◽

S. NAMPALLI ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Biological Evaluation ◽

Anti Hiv Agents ◽

Synthesis And Biological Evaluation ◽

Anti Hiv

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Towards the enantioselective synthesis of anti-HIV agents litseaverticillols C and K from d-glucose

Tetrahedron ◽

10.1016/j.tet.2007.01.037 ◽

2007 ◽

Vol 63 (12) ◽

pp. 2613-2621 ◽

Cited By ~ 8

Author(s):

Debendra K. Mohapatra ◽

Dhananjoy Mondal ◽

Mukund K. Gurjar

Keyword(s):

Enantioselective Synthesis ◽

Anti Hiv Agents ◽

Anti Hiv

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