Dynamic kinetic resolution of a tertiary alcohol

2020 ◽  
Vol 56 (19) ◽  
pp. 2885-2888 ◽  
Author(s):  
Franziska Kühn ◽  
Satoko Katsuragi ◽  
Yasuhiro Oki ◽  
Cedric Scholz ◽  
Shuji Akai ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Tertiary Alcohol ◽  
Dynamic Kinetic Resolution

The first example of a dynamic kinetic resolution of a racemic tertiary alcohol is presented. By combining a lipase-catalyzed kinetic resolution and a racemization with an oxovanadium-catalyst, the ester was obtained in 77% yield and with >99% ee.

Development of a Robust and Highly Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

2020 ◽  
Vol 24 (6) ◽  
pp. 1164-1174
Author(s):  
Austin G. Smith ◽  
Matthew M. Bio ◽  
John T. Colyer ◽  
Khalid Diker ◽  
Gilles Gorins ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides

2021 ◽  
Author(s):  
Linghui Qian ◽  
Ling-Fei Tao ◽  
Wen-Tao Wang ◽  
Ehtesham Jameel ◽  
Zhang-Hong Luo ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution

2021 ◽  
pp. 152764
Author(s):  
Jacques Le Paih ◽  
Dane A. Goff ◽  
Rajinder Singh ◽  
Simon J. Shaw
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

An Efficient Dynamic Kinetic Resolution of N-Heterocyclic 1,2-Amino Alcohols

2011 ◽  
Vol 353 (13) ◽  
pp. 2321-2327 ◽  
Author(s):  
Richard Lihammar ◽  
Renaud Millet ◽  
Jan-E. Bäckvall
Keyword(s):  
Kinetic Resolution ◽  
Amino Alcohols ◽  
Dynamic Kinetic Resolution

ChemInform Abstract: Stereospecific Amination by Dynamic Kinetic Resolution Utilizing 2- Oxoimidazolidine-4-carboxylate as a Novel Chiral Auxiliary.

ChemInform ◽  
2010 ◽  
Vol 27 (10) ◽  
pp. no-no
Author(s):  
H. KUBOTA ◽  
A. KUBO ◽  
M. TAKAHASHI ◽  
R. SHIMIZU ◽  
T. DA-TE ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Chiral Auxiliary ◽  
Dynamic Kinetic Resolution
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