Oral administration of Lactococcus lactis WHH2078 alleviates depressive and anxiety symptoms in mice with induced chronic stress

2022 ◽  
Author(s):  
Kan Gao ◽  
Aitak Farzi ◽  
Xueqin Ke ◽  
Yunxia Yu ◽  
Cailin Chen ◽  
...  

Depression is a mood disorder with a high prevalence rate globally, which is associated with abnormalities in 5-hydroxytryptamine (5-HT) metabolism. Emerging evidence suggests that certain probiotics that modulate 5-HT metabolism...

2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Gule Rana ◽  
Noreen Akmal ◽  
Naseem Akhtar

Hepatitis B during pregnancy is an important cause of morbidity and mortality. A study was conducted on 1000 pregnant females at Sir Ganga Ram Hospital to find out the prevalence of Hepatitis B in pregnant females. 18 (1.8%) were found to be hepatitis B surface antigen positive thus showing a high prevalence rate for this disease in the study population.


Author(s):  
Poornima Jalawadi ◽  
Aiyanna PP

Pilonidal Sinus (PNS) is a commonest presentation in surgical practice with a high prevalence rate at more than 1 million cases per year in India, where as incidence is about 26 per 1,00,000 population. A 30-year-old male patient presented with PNS after an unsuccessful excision followed by antibiotic therapy. The challenge in this case was not only to excise the tract but also preventing its recurrence. Adopting the principles of Vranopakramas using Ksharakarma, Utsadana karma described in Ayurveda helped to manage the PNS effectively without any recurrence after 32 months of follow-up.


Author(s):  
Mike Namaka ◽  
Carol St-Laurent ◽  
Raelene Vandenbosch ◽  
Ranbir Gill ◽  
Dana Ruhlen ◽  
...  

Although a rare disease, multiple sclerosis (MS) has a high prevalence rate in Canada and affects many Canadians and their families. An autoimmune disease of the central nervous system, it results in the destruction of the myelin sheath that surrounds the nerve axons. High-dose IV steroid therapy is often used to treat an acute exacerbation in MS. Steroids have immunosuppressant effects that work to decrease the autoimmune pathology component of the disease and to reduce the inflammation around the nerve axon, thereby promoting closer contact of the damaged myelin and subsequently partially restoring adequate electrical nerve conduction to reduce symptoms. The high prevalence rate of MS in Canada makes it vital for pharmacists to become more aware of the different aspects of the disease and how these relate to therapy. The pharmacist should be aware of the adverse effects and impact of high-dose IV steroids in MS patients. The purpose of this review is threefold: 1) to provide a better understanding of MS pathology; 2) to contribute a systematic review of steroids; and 3) to assist in the clinical decision-making process and in the counselling requirements for patients on high-dose steroids.


2006 ◽  
Vol 43 (4) ◽  
pp. 512-517 ◽  
Author(s):  
Masafumi Kuzuya ◽  
Yuichiro Masuda ◽  
Yoshihisa Hirakawa ◽  
Mitsunaga Iwata ◽  
Hiromi Enoki ◽  
...  

2005 ◽  
Vol 73 (1) ◽  
pp. 87-91 ◽  
Author(s):  
FERNANDO RAMOS ◽  
MANUEL RAMIRO ◽  
ALEJANDRO GÓMEZ ◽  
EMMA I. MELENDRO ◽  
GABRIELA GARCÍA ◽  
...  

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