Tuning Non-Radiative Decay Channels via Symmetric/Asymmetric Substituent Effects on Phenazine Derivative and Their Phototherapy Switch Between Dynamic and Thermal Process

2022 ◽  
Author(s):  
玉轩 李 ◽  
Keke Ding ◽  
Haozhong Wu ◽  
Qing Wan ◽  
Yao Ma ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Thermal Process ◽  
Radiative Decay ◽  
Substituent Effects ◽  
Decay Process ◽  
Decay Channels ◽  
Phenazine Derivative

Recently, some discovery based on non-radiative decay process leading to photodynamic therapy or photothermal therapy has become an attaching hotspot, and how to achieve better performance is becoming important in...

scholarly journals Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Surface Engineering ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Cargo Delivery ◽  
Bio Imaging ◽  
Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

Phototherapy and multimodal imaging of cancers based on perfluorocarbon nanomaterials

2021 ◽  
Author(s):  
Zhaoguo Han ◽  
xianshuang tu ◽  
Lina Qiao ◽  
Yige Sun ◽  
Zibo Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Side Effects ◽  
Cancer Treatment ◽  
Photothermal Therapy ◽  
Multimodal Imaging

Phototherapy, such as photodynamic therapy (PDT) and photothermal therapy (PTT) possesses unique characteristics of non-invasiveness and minimal side effects in cancer treatment, compared with conventional therapies. However, the ubiquitous tumor...

scholarly journals Photo-Based Nanomedicines Using Polymeric Systems in the Field of Cancer Imaging and Therapy

Biomedicines ◽  
2020 ◽  
Vol 8 (12) ◽  
pp. 618
Author(s):  
Patihul Husni ◽  
Yuseon Shin ◽  
Jae Chang Kim ◽  
Kioh Kang ◽  
Eun Seong Lee ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Optical Imaging ◽  
Photothermal Therapy ◽  
Cancer Imaging ◽  
Polymeric Systems ◽  
Therapeutic Applications ◽  
Shed Light

The use of photo-based nanomedicine in imaging and therapy has grown rapidly. The property of light in converting its energy into different forms has been exploited in the fields of optical imaging (OI) and phototherapy (PT) for diagnostic and therapeutic applications. The development of nanotechnology offers numerous advantages to overcome the challenges of OI and PT. Accordingly, in this review, we shed light on common photosensitive agents (PSAs) used in OI and PT; these include fluorescent and bioluminescent PSAs for OI or PT agents for photodynamic therapy (PDT) and photothermal therapy (PTT). We also describe photo-based nanotechnology systems that can be used in photo-based diagnostics and therapies by using various polymeric systems.

scholarly journals Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics

2018 ◽  
Vol 6 (4) ◽  
pp. 746-765 ◽  
Author(s):  
Houjuan Zhu ◽  
Penghui Cheng ◽  
Peng Chen ◽  
Kanyi Pu
Keyword(s):  
Photodynamic Therapy ◽  
Side Effects ◽  
Spatial Resolution ◽  
Photothermal Therapy ◽  
Normal Tissue ◽  
Recent Progress ◽  
Near Infrared ◽  
Tumor Ablation ◽  
Ablation Efficiency ◽  
Excellent Spatial Resolution

Phototherapies including photothermal therapy (PTT) and photodynamic therapy (PDT) have gained considerable attention due to their high tumor ablation efficiency, excellent spatial resolution and minimal side effects on normal tissue.

scholarly journals A covalent organic framework as a nanocarrier for synergistic phototherapy and immunotherapy

2020 ◽  
Vol 8 (25) ◽  
pp. 5451-5459 ◽  
Author(s):  
Ying Zhou ◽  
Sainan Liu ◽  
Chunling Hu ◽  
Lihan Cai ◽  
Maolin Pang
Keyword(s):  
Photodynamic Therapy ◽  
Local Recurrence ◽  
Cancer Treatment ◽  
Photothermal Therapy ◽  
Tumor Metastasis ◽  
Primary Tumors ◽  
Treatment Methods ◽  
Covalent Organic Framework ◽  
Organic Framework

As traditional cancer treatment methods, photodynamic therapy (PDT) and photothermal therapy (PTT) can eliminate primary tumors, but they cannot inhibit extensive tumor metastasis and local recurrence.

Concurrent photothermal therapy and photodynamic therapy for cutaneous squamous cell carcinoma by gold nanoclusters under a single NIR laser irradiation

2019 ◽  
Vol 7 (44) ◽  
pp. 6924-6933 ◽  
Author(s):  
Pei Liu ◽  
Weitao Yang ◽  
Lei Shi ◽  
Haiyan Zhang ◽  
Yan Xu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Laser Irradiation ◽  
Squamous Cell ◽  
Photothermal Therapy ◽  
Gold Nanoclusters ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Single Drug ◽  
Nir Laser

The concurrent photothermal and photodynamic therapy of cutaneous squamous cell carcinoma by a single drug of Au25(Capt)18 nanoclusters is demonstrated, together with a preliminary immune response study conducted under a single NIR laser irradiation.

A Near-Infrared Small Molecule Coupled with Rigidness and Flexibility for High-Performance Multimodal Imaging-Guided Photodynamic and Photothermal Synergistic Therapy

2021 ◽  
Author(s):  
Xiaozhen Li ◽  
Fang Fang ◽  
Bo Sun ◽  
Chao YIN ◽  
Jihua Tan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Application ◽  
Small Molecule ◽  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
High Performance ◽  
Near Infrared ◽  
The Other ◽  
Lesion Site ◽  
Comprehensive Information

Photodynamic therapy (PDT) synergized photothermal therapy (PTT) shows superior clinical application prospect than single PDT or PTT. On the other hand, multimodal imaging can delineate comprehensive information of lesion site...

Non-radiative decay of an eumelanin monomer: to be or not to be planar

2019 ◽  
Vol 21 (12) ◽  
pp. 6635-6642 ◽  
Author(s):  
Paulami Ghosh ◽  
Debashree Ghosh
Keyword(s):  
Radiative Decay ◽  
Decay Channels

The planar and nonplanar non-radiative decay channels of eumelanin monomer.

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