The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro
Keyword(s):
The mitotic regulator Hec1 (highly expressed in cancer), is a member of a conserved Ndc80 (nuclear division cycle 80) complex that regulates mitotic processes. We find that Hec1 is consistently overexpressed in human prostate cancer and Hec1 is closely linked with human prostate cancer progression through the meditator LncRNA BX647187. Our studies may contribute to understand the molecular mechanism of PCa pathogenesis and clinical therapy.
2017 ◽
Vol 51
(4)
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pp. 1089-1103
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2006 ◽
Vol 118
(9)
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pp. 2123-2131
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2016 ◽
2017 ◽
2007 ◽
Vol 13
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pp. 6040-6048
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1994 ◽
Vol 9
(1)
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pp. 19-27
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