Weighting of Amplitude and Formant Rise Time Cues by School-Aged Children: A Mismatch Negativity Study

2018 ◽  
Vol 61 (5) ◽  
pp. 1322-1333
Author(s):  
Varghese Peter ◽  
Marina Kalashnikova ◽  
Denis Burnham
Keyword(s):  
Rise Time ◽  
Mismatch Negativity ◽  
Standard Stimulus ◽  
Oddball Paradigm ◽  
Acoustic Cues ◽  
Older Children ◽  
Deviant Stimulus ◽  
Cue Weighting ◽  
School Aged Children ◽  
Optimal Weights

Purpose An important skill in the development of speech perception is to apply optimal weights to acoustic cues so that phonemic information is recovered from speech with minimum effort. Here, we investigated the development of acoustic cue weighting of amplitude rise time (ART) and formant rise time (FRT) cues in children as measured by mismatch negativity (MMN). Method Twelve adults and 36 children aged 6–12 years listened to a /ba/–/wa/ contrast in an oddball paradigm in which the standard stimulus had the ART and FRT cues of /ba/. In different blocks, the deviant stimulus had either the ART or FRT cues of /wa/. Results The results revealed that children younger than 10 years were sensitive to both ART and FRT cues whereas 10- to 12-year-old children and adults were sensitive only to FRT cues. Moreover, children younger than 10 years generated a positive mismatch response, whereas older children and adults generated MMN. Conclusion These results suggest that preattentive adultlike weighting of ART and FRT cues is attained only by 10 years of age and accompanies the change from mismatch response to the more mature MMN response. Supplemental Material https://doi.org/10.23641/asha.6207608

Is There a Mismatch Negativity Analogue in the Olfactory Event-Related Potential?

1999 ◽  
Vol 13 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Kerstin Krauel ◽  
Philipp Schott ◽  
Bernfried Sojka ◽  
Bettina M. Pause ◽  
Roman Ferstl
Keyword(s):  
Mismatch Negativity ◽  
Standard Stimulus ◽  
Event Related Potential ◽  
Oddball Paradigm ◽  
Distractor Task ◽  
Deviant Stimulus ◽  
Negative Deflection ◽  
Odor Quality ◽  
Acoustic Stimuli ◽  
Male Subjects

Abstract The mismatch negativity (MMN) is thought to indicate automatic stimulus discrimination in response to acoustic stimuli. In the present study six male subjects were presented with the odors linalool and eugenol within a passive oddball-paradigm. The subjects were instructed to ignore the odors and concentrate on an auditory distractor task. In two sessions each odor served once as the standard stimulus and once as the deviant stimulus. Both odors when presented as deviants led to a negative deflection of the olfactory event-related potential (OERP) between 500-600 ms. After 600 ms the waveforms in response to the deviants were differentially influenced by odor quality. Although the present study should be understood as exploratory, the results suggest the existence of an early mismatch detector in the olfactory modality independent of attention and odor quality.

scholarly journals Short- and long-term habituation of auditory event-related potentials in the rat

F1000Research ◽  
2013 ◽  
Vol 2 ◽  
pp. 182
Author(s):  
Kestutis Gurevicius ◽  
Arto Lipponen ◽  
Rimante Minkeviciene ◽  
Heikki Tanila
Keyword(s):  
Mismatch Negativity ◽  
Standard Stimulus ◽  
Specific Effect ◽  
Event Related Potentials ◽  
Auditory Evoked Potential ◽  
Oddball Paradigm ◽  
Evoked Responses ◽  
Auditory Oddball ◽  
Long Duration ◽  
Related Potentials

An auditory oddball paradigm in humans generates a long-duration cortical negative potential, often referred to as mismatch negativity. Similar negativity has been documented in monkeys and cats, but it is controversial whether mismatch negativity also exists in awake rodents. To this end, we recorded cortical and hippocampal evoked responses in rats during alert immobility under a typical passive oddball paradigm that yields mismatch negativity in humans. The standard stimulus was a 9 kHz tone and the deviant either 7 or 11 kHz tone in the first condition. We found no evidence of a sustained potential shift when comparing evoked responses to standard and deviant stimuli. Instead, we found repetition-induced attenuation of the P60 component of the combined evoked response in the cortex, but not in the hippocampus. The attenuation extended over three days of recording and disappeared after 20 intervening days of rest. Reversal of the standard and deviant tones resulted is a robust enhancement of the N40 component not only in the cortex but also in the hippocampus. Responses to standard and deviant stimuli were affected similarly. Finally, we tested the effect of scopolamine in this paradigm. Scopolamine attenuated cortical N40 and P60 as well as hippocampal P60 components, but had no specific effect on the deviant response. We conclude that in an oddball paradigm the rat demonstrates repetition-induced attenuation of mid-latency responses, which resembles attenuation of the N1-component of human auditory evoked potential, but no mismatch negativity.

scholarly journals Neural detection of changes in amplitude rise time in infancy.

2021 ◽  
Author(s):  
Áine Ní Choisdealbha ◽  
Adam Attaheri ◽  
Sinead Rocha ◽  
Perrine Brusini ◽  
Sheila Flanagan ◽  
...  
Keyword(s):  
Speech Processing ◽  
Rise Time ◽  
Mismatch Negativity ◽  
Neural Processing ◽  
Amplitude Envelope ◽  
Acoustic Cues ◽  
Perceptual Sensitivity ◽  
Language Difficulties ◽  
Neural Entrainment ◽  
First Time

Amplitude rise times play a crucial role in the perception of rhythm in speech, and reduced perceptual sensitivity to differences in rise time is related to developmental language difficulties. Amplitude rise times also play a mechanistic role in neural entrainment to the speech amplitude envelope. Using an ERP paradigm, here we examined for the first time whether infants at the ages of seven and eleven months exhibit an auditory mismatch response to changes in the rise times of simple repeating auditory stimuli. We found that infants exhibited a mismatch response to the oddball rise time that was more positive at seven than eleven months of age. At eleven months, there was a left-lateralised shift to a mismatch negativity. Infants’ ability to detect changes in rise time was generally robust, with a range of oddball stimuli with different rise times each eliciting a mismatch response from 85% of infants. A lateralised effect indicated that the size of the mismatch response varied as the change in rise time became easier to detect. The mismatch response to the different rise time oddballs also stabilised as infants got older. The results indicate that neural processing of changes in rise time develops early in life, supporting the possibility that early speech processing is facilitated by neural sensitivity to these acoustic cues to rhythm.

scholarly journals Neural Representation of the English Vowel Feature [High]: Evidence From /ε/ vs. /ɪ/

2021 ◽  
Vol 15 ◽  
Author(s):  
Yan H. Yu ◽  
Valerie L. Shafer
Keyword(s):  
Amplitude Modulation ◽  
Speech Processing ◽  
Mismatch Negativity ◽  
Order Effect ◽  
Neural Representation ◽  
Oddball Paradigm ◽  
Prototype Model ◽  
Deviant Stimulus ◽  
Processing Asymmetries

Many studies have observed modulation of the amplitude of the neural index mismatch negativity (MMN) related to which member of a phoneme contrast [phoneme A, phoneme B] serves as the frequent (standard) and which serves as the infrequent (deviant) stimulus (i.e., AAAB vs. BBBA) in an oddball paradigm. Explanations for this amplitude modulation range from acoustic to linguistic factors. We tested whether exchanging the role of the mid vowel /ε/ vs. high vowel /ɪ/ of English modulated MMN amplitude and whether the pattern of modulation was compatible with an underspecification account, in which the underspecified height values are [−high] and [−low]. MMN was larger for /ε/ as the deviant, but only when compared across conditions to itself as the standard. For the within-condition comparison, MMN was larger to /ɪ/ deviant minus /ε/ standard than to the reverse. A condition order effect was also observed. MMN amplitude was smaller to the deviant stimulus if it had previously served as the standard. In addition, the amplitudes of late discriminative negativity (LDN) showed similar asymmetry. LDN was larger for deviant /ε/ than deviant /ɪ/ when compared to themselves as the standard. These findings were compatible with an underspecification account, but also with other accounts, such as the Natural Referent Vowel model and a prototype model; we also suggest that non-linguistic factors need to be carefully considered as additional sources of speech processing asymmetries.

scholarly journals Short- and long-term habituation of auditory event-related potentials in the rat

F1000Research ◽  
2014 ◽  
Vol 2 ◽  
pp. 182 ◽  
Author(s):  
Kestutis Gurevicius ◽  
Arto Lipponen ◽  
Rimante Minkeviciene ◽  
Heikki Tanila
Keyword(s):  
Mismatch Negativity ◽  
Standard Stimulus ◽  
Specific Effect ◽  
Event Related Potentials ◽  
Auditory Evoked Potential ◽  
Oddball Paradigm ◽  
Evoked Responses ◽  
Auditory Oddball ◽  
Long Duration ◽  
Related Potentials

An auditory oddball paradigm in humans generates a long-duration cortical negative potential, often referred to as mismatch negativity. Similar negativity has been documented in monkeys and cats, but it is controversial whether mismatch negativity also exists in awake rodents. To this end, we recorded cortical and hippocampal evoked responses in rats during alert immobility under a typical passive oddball paradigm that yields mismatch negativity in humans. The standard stimulus was a 9 kHz tone and the deviant either 7 or 11 kHz tone in the first condition. We found no evidence of a sustained potential shift when comparing evoked responses to standard and deviant stimuli. Instead, we found repetition-induced attenuation of the P60 component of the combined evoked response in the cortex, but not in the hippocampus. The attenuation extended over three days of recording and disappeared after 20 intervening days of rest. Reversal of the standard and deviant tones resulted is a robust enhancement of the N40 component not only in the cortex but also in the hippocampus. Responses to standard and deviant stimuli were affected similarly. Finally, we tested the effect of scopolamine in this paradigm. Scopolamine attenuated cortical N40 and P60 as well as hippocampal P60 components, but had no specific effect on the deviant response. We conclude that in an oddball paradigm the rat demonstrates repetition-induced attenuation of mid-latency responses, which resembles attenuation of the N1-component of human auditory evoked potential, but no mismatch negativity.

scholarly journals Sugar-Sweetened Beverage Consumption Status and Its Association with Childhood Obesity among Chinese Children Aged 6–17 Years

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2211
Author(s):  
Qian Gan ◽  
Peipei Xu ◽  
Titi Yang ◽  
Wei Cao ◽  
Juan Xu ◽  
...  
Keyword(s):  
Childhood Obesity ◽  
Urban Areas ◽  
Study Data ◽  
Chinese Children ◽  
Obesity Prevalence ◽  
Older Children ◽  
Sugar Sweetened Beverage ◽  
School Aged Children ◽  
Chinese School ◽  
And Control

Objective: There is a remarkable growth in sugar-sweetened (SSB) production and obesity prevalence among school-aged children in China. This paper describes SSB consumption and its association with obesity among Chinese children aged 6–17 years in 2012. Methods: in total, 25,553 children aged 6~17 years enrolled in the China Nutrition and Health Surveillance 2010–2013 were included in this study. Data of SSB consumption frequency and quantity were obtained from a food frequency questionnaire, and the children’s nutritional status was assessed. Multivariate logistic regression was used to evaluate the association between SSB consumption and obesity status. Results: SSB intake was estimated as 181.0 g/day, occurring 2.2 times/week. Older children, males, children from urban areas, and children with higher socioeconomic status were more likely to consume SSBs. Children who consumed SSBs 1~<5 times/week (11.7%) and >5 times/week (12.9%) were more likely to be overweight/obesity than those who consumed SSBs less than once/week. Conclusion: SSB consumption was common among Chinese school-aged children, especially among males, older children, and children from urban areas. High consumption of SSBs was associated with a higher prevalence of overweight/obesity. Actions and plans are required to reduce SSB consumption and control childhood obesity in China.

Familiarity of Speaker Accent on Irish Children’s Performance on a Sentence Comprehension Task

2011 ◽  
Vol 18 (1) ◽  
pp. 1-17
Author(s):  
Claire O’Connor ◽  
Fiona E. Gibbon
Keyword(s):  
Sentence Comprehension ◽  
Clinical Implications ◽  
Syntactic Complexity ◽  
Typically Developing ◽  
Older Children ◽  
School Aged Children ◽  
Comprehension Task ◽  
Computer Based

Objective: This study sought to determine whether children’s performance on a sentence comprehension task is affected when sentences are spoken in an unfamiliar native accent. Method: Fifty typically developing school-aged children living in Southern Ireland (Cork) participated; 25 in a younger group (mean 7;08 years) and 25 in an older group (mean 9;09 years). The children completed a computer-based comprehension task during which 20 sentences were spoken in a Cork accent (familiar) and 20 in a Tyrone accent (unfamiliar). The sentences were matched for syllable length and syntactic complexity. Main results: The younger children made significantly more errors when sentences were spoken in an unfamiliar accent. The older children made a similar number of incorrect responses to both familiar and unfamiliar accents. Conclusion: Younger children’s performance on comprehension tasks may be reduced when sentences are spoken in an unfamiliar accent. Possible explanations and the clinical implications are discussed.

The Neurophysiological Basis of the Auditory Continuity Illusion: A Mismatch Negativity Study

2003 ◽  
Vol 15 (5) ◽  
pp. 747-758 ◽  
Author(s):  
Christophe Micheyl ◽  
Robert P. Carlyon ◽  
Yury Shtyrov ◽  
Olaf Hauk ◽  
Tara Dodson ◽  
...  
Keyword(s):  
Mismatch Negativity ◽  
Sudden Change ◽  
Frequency Region ◽  
Neural Mechanisms ◽  
Oddball Paradigm ◽  
Standard Type ◽  
Upper Limit ◽  
Noise Frequency ◽  
Filtered Noise ◽  
Neurophysiological Basis

A sound turned off for a short moment can be perceived as continuous if the silent gap is filled with noise. The neural mechanisms underlying this “continuity illusion” were investigated using the mismatch negativity (MMN), an eventrelated potential reflecting the perception of a sudden change in an otherwise regular stimulus sequence. The MMN was recorded in four conditions using an oddball paradigm. The standards consisted of 500-Hz, 120-msec tone pips that were either physically continuous (Condition 1) or were interrupted by a 40-msec silent gap (Condition 2). The deviants consisted of the interrupted tone, but with the silent gap filled by a burst of bandpass-filtered noise. The noise either occupied the same frequency region as the tone and elicited the continuity illusion (Conditions 1a and 2a), or occupied a remote frequency region and did not elicit the illusion (Conditions 1b and 2b). We predicted that, if the continuity illusion is determined before MMN generation, then, other things being equal, the MMN should be larger in conditions where the deviants are perceived as continuous and the standards as interrupted or vice versa, than when both were perceived as continuous or both interrupted. Consistent with this prediction, we observed an interaction between standard type and noise frequency region, with the MMN being larger in Condition 1a than in Condition 1b, but smaller in Condition 2a than in Condition 2b. Because the subjects were instructed to ignore the tones and watch a silent movie during the recordings, the results indicate that the continuity illusion can occur outside the focus of attention. Furthermore, the latency of the MMN (less than approximately 200 msec postdeviance onset) places an upper limit on the stage of neural processing responsible for the illusion.

Impact of Chronic Cannabis Use on Auditory Mismatch Negativity Generation in Schizophrenia Patients

2018 ◽  
Vol 52 (03) ◽  
pp. 126-133 ◽  
Author(s):  
Patrik Roser ◽  
Eva-Maria Pichler ◽  
Benedikt Habermeyer ◽  
Wolfram Kawohl ◽  
Georg Juckel
Keyword(s):  
Cognitive Functioning ◽  
Cognitive Performance ◽  
Mismatch Negativity ◽  
Cannabis Use ◽  
Oddball Paradigm ◽  
Healthy Controls ◽  
Characteristic Finding ◽  
Auditory Oddball ◽  
Cannabis Use Disorders ◽  
Auditory Oddball Paradigm

Abstract Introduction Cannabis use disorders (CUD) are highly prevalent among patients with schizophrenia (SCZ). Deficient mismatch negativity (MMN) generation is a characteristic finding in SCZ patients and cannabis users. This study therefore examined the effects of CUD on MMN generation in SCZ patients. Methods Twenty SCZ − CUD patients, 21 SCZ+CUD patients, and 20 healthy controls (HC) were included in this study. MMN to frequency and duration deviants was elicited within an auditory oddball paradigm and recorded by 32 channel EEG. Results As expected, SCZ − CUD patients showed reduced frontocentral MMN amplitudes to duration deviants compared to HC. Interestingly, SCZ+CUD patients demonstrated greater MMN amplitudes to duration deviants compared to SCZ − CUD patients at central electrodes with no differences compared to HC. Discussion These results demonstrate that comorbid cannabis use in SCZ patients might be associated with superior cognitive functioning. It can be assumed that the association between cannabis use and better cognitive performance may be due to a subgroup of cognitively less impaired SCZ patients characterized by lower genetic vulnerability for psychosis.

Saliency of Vowel Features in Neural Responses of Cochlear Implant Users

2018 ◽  
Vol 49 (6) ◽  
pp. 388-397
Author(s):  
François Prévost ◽  
Alexandre Lehmann
Keyword(s):  
Speech Recognition ◽  
Cochlear Implant ◽  
Fundamental Frequency ◽  
Mismatch Negativity ◽  
Free Field ◽  
Event Related Potentials ◽  
Oddball Paradigm ◽  
Aural Rehabilitation ◽  
Spectral Components ◽  
Related Potentials

Cochlear implants restore hearing in deaf individuals, but speech perception remains challenging. Poor discrimination of spectral components is thought to account for limitations of speech recognition in cochlear implant users. We investigated how combined variations of spectral components along two orthogonal dimensions can maximize neural discrimination between two vowels, as measured by mismatch negativity. Adult cochlear implant users and matched normal-hearing listeners underwent electroencephalographic event-related potentials recordings in an optimum-1 oddball paradigm. A standard /a/ vowel was delivered in an acoustic free field along with stimuli having a deviant fundamental frequency (+3 and +6 semitones), a deviant first formant making it a /i/ vowel or combined deviant fundamental frequency and first formant (+3 and +6 semitones /i/ vowels). Speech recognition was assessed with a word repetition task. An analysis of variance between both amplitude and latency of mismatch negativity elicited by each deviant vowel was performed. The strength of correlations between these parameters of mismatch negativity and speech recognition as well as participants’ age was assessed. Amplitude of mismatch negativity was weaker in cochlear implant users but was maximized by variations of vowels’ first formant. Latency of mismatch negativity was later in cochlear implant users and was particularly extended by variations of the fundamental frequency. Speech recognition correlated with parameters of mismatch negativity elicited by the specific variation of the first formant. This nonlinear effect of acoustic parameters on neural discrimination of vowels has implications for implant processor programming and aural rehabilitation.

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