Polyclonal immunoglobulin G deposition disease: A unique entity

1998 ◽  
Vol 32 (2) ◽  
pp. 328-333 ◽  
Author(s):  
GS Markowitz ◽  
PL Fine ◽  
CL Kunis ◽  
Z Yu ◽  
VD D'Agati
2011 ◽  
Vol 46 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Rattana Wongchuphan ◽  
Beng Ti Tey ◽  
Wen Siang Tan ◽  
Senthil Kumar Subramanian ◽  
Farah Saleena Taip ◽  
...  

1994 ◽  
Vol 67 (800) ◽  
pp. 770-774 ◽  
Author(s):  
A Jiménez-Heffernan ◽  
J L Villanueva ◽  
A Moral ◽  
A Rebollo ◽  
F M González ◽  
...  

2020 ◽  
Author(s):  
Anri Sawada ◽  
Masayoshi Okumi ◽  
Shigeru Horita ◽  
Tomomi Tamura ◽  
Sekiko Taneda ◽  
...  

Abstract The authors have withdrawn this preprint due to author disagreement.


2020 ◽  
Vol 70 (7) ◽  
pp. 463-469
Author(s):  
Hirofumi Watanabe ◽  
Yoichi Takeuchi ◽  
Shinji Taniuchi ◽  
Hiroshi Sato ◽  
Yasuhiro Nakamura ◽  
...  

Placenta ◽  
2019 ◽  
Vol 83 ◽  
pp. e86-e87
Author(s):  
Carlos Mario Rodríguez Colorado ◽  
Manuela Velasquez Berrío ◽  
Diana Carolina Rúa Molina ◽  
Angela María Álvarez Gomez ◽  
Angela Patricia Cadavid Jaramillo

AIChE Journal ◽  
2021 ◽  
Author(s):  
Wenning Chu ◽  
Sobhana A. Sripada ◽  
Hannah R. Reese ◽  
Dipendra Bhandari ◽  
Augustus Adams ◽  
...  

2020 ◽  
Vol 9 (4) ◽  
pp. 949
Author(s):  
Cinzia Milito ◽  
Francesco Cinetto ◽  
Valentina Megna ◽  
Giuseppe Spadaro ◽  
Isabella Quinti ◽  
...  

Enteropathy may be the first presentation of immunodeficiency or it may occur during the course of the disease and in association with malabsorption in patients affected by primary antibody diseases. For these patients, immunoglobulin G (IgG) replacement therapy prevents infectious and non-infectious complications. Nonetheless some patients cannot achieve optimal IgG trough levels, even when treated with high Ig doses in absence of protein-losing syndromes. We investigated seven patients affected by common variable immunodeficiencies (CVIDs) and treated with high Ig doses (600–800 mg/kg/month) showing low IgG trough level. Patients underwent abdominal scintigraphy with human polyclonal immunoglobulin G labeled with 99mTc and with white blood cells labeled by 111 Indium-oxinate to investigate asymptomatic bowel inflammation. A concentration of labeled leukocytes in abdominal segments greater than that observed with human polyclonal immunoglobulin G was evident only in one patient. In five patients a slight concentration of both radiopharmaceuticals was reported, due to mild intestinal inflammatory response. These data might be related to mild increase of capillary permeability in the absence of inflammation leukocyte mediated. This study discloses a new cause of IgG-accelerated catabolism due to inflammatory bowel conditions without diarrhea in CVID patients.


1982 ◽  
Vol 28 (5) ◽  
pp. 1103-1107 ◽  
Author(s):  
H von Schenck ◽  
A O Grubb

Abstract Radioimmunoassays of glucagon in plasma may be complicated by interaction with other substances of high molecular mass. Precipitates of such substances with ammonium sulfate showed, after isoelectric focusing, two fractions having glucagon immunoreactivity. One fraction (pl approximately 10) evidently is associated with the Fc portion (but not the Fab portion) of purified polyclonal immunoglobulin G (IgG). Equal amounts of purified monoclonal IgG of various subclasses, especially IgG 1, gave different "glucagon" readings, suggesting that some IgG may interfere more strongly than others. The other fraction (pI 5-6) appeared less consistently, and on gel chromatography appeared to be slightly larger than IgG. Together these fractions add about 50-100 ng/L to the immunoreactive glucagon values in plasma. Therefore methods in which glucagon is extracted before assay should be used for determining the concentration of glucagon present physiologically.


Sign in / Sign up

Export Citation Format

Share Document