Lichenoide Dermatosen der Vulva

2019 ◽  
Vol 45 (08/09) ◽  
pp. 377-385
Author(s):  
F. Gieseking ◽  
I. Moll

ZusammenfassungDieser Artikel gibt einen aktuellen Überblick über die 3 lichenoiden Erkrankungen der Vulva. Es handelt sich um chronische Dermatosen. Sie verursachen nicht notwendigerweise Beschwerden und fallen bisweilen erst bei sorgfältiger Anamnese und der gynäkologischen Untersuchung auf. Während der vulväre Lichen simplex chronicus als harmlos angesehen werden kann, führen Lichen planus und Lichen sclerosus zu langanhaltenden und hartnäckigen Beschwerden. Der Lichen sclerosus und der Lichen planus werden als Risikofaktoren für die Entwicklung eines HPV-negativen Vulvakarzinoms angesehen. Die meisten Frauen mit malignen Befunden an der Vulva hatten zuvor häufig einen Lichen sclerosus oder einen Lichen planus. Die Ursachen der lichenoiden Erkrankungen gelten als unbekannt. Eine Störung des Immunsystems wird angenommen. Ein abschließendes Urteil zu diesen Erkrankungen ist noch nicht möglich.

2020 ◽  
Vol 4 (10) ◽  
pp. 617-624
Author(s):  
O.V. Parygina ◽  
◽  
I.O. Smirnova ◽  
M.V. Oganesyan ◽  
Y.G. Petunova ◽  
...  

Lichenoid vulvar dermatoses are a heterogeneous group of diseases characterized by a number of overlapping signs and/or morphological features. Clinical similarity is accounted for by the appearance of small discrete papules with closely adjacent superficial squamae. The prototype of lichenoid dermatoses is lichen ruber planus. Histologically, lichenoid pattern is characterized by basal epithelial cell damage and a band-like infiltrate in the upper dermis. The International Society on Vulvovaginal Diseases categorizes lichen ruber planus and early lichen sclerosus as dermatoses with this histological pattern. Some authors also classify plasma cell (Zoon) vulvitis as lichenoid vulvar dermatoses. The cause of diagnostic errors lies in the similarity of the clinical and histological presentations of lichenoid vulvar dermatoses. Dermatoscopy should be considered as an additional diagnostic test. Only few studies address the key dermatoscopic signs of vulvar dermatoses. Histological study is important for the differential diagnosis. However, at some stages of disease evolution, vulvar dermatoses can have an overlapping histological pattern. This paper summarizes the data on the clinical, histological, and dermatoscopic presentation of the most common lichenoid vulvar dermatoses, i.e., lichen planus, lichen sclerosus, lichen simplex chronicus, and plasma cell vulvitis. KEYWORDS: lichenoid dermatoses, vulvar dermatoses, lichen sclerosus, lichen planus, lichen simplex chronicus, plasma cell vulvitis, Zoon vulvitis, dermoscopy. FOR CITATION: Parygina O.V., Smirnova I.O., Oganesyan M.V. et al. Lichenoid vulvar dermatoses: clinical presentation, morphology, and dermatoscopic signs. Russian Medical Inquiry. 2020;4(10):617–624. DOI: 10.32364/2587-6821-2020-4-10-617-624.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Jean Doyen ◽  
Stéphanie Demoulin ◽  
Katty Delbecque ◽  
Frédéric Goffin ◽  
Frédéric Kridelka ◽  
...  

The objective of this paper is to present general considerations which should be kept in mind by clinicians in charge of women with vulvar diseases. Four representative vulvar dermatoses are described. Lichen simplex chronicus is a pathological condition related to chemical and mechanical irritant agents. Detrimental effects of these irritants, in the presence of other dermatoses, have to be considered when therapeutic responses are unsatisfactory. Lichen sclerosus is the most common vulvar dermatosis in elderly. However, it should be kept in mind that it may be diagnosed at any age. Lichen planus, in spite of sharing a similar range of etiological factors with lichen sclerosus, is a very distinct entity. Finally, Paget’s disease, although rare, is also described especially because of the challenge it represents both clinically and therapeutically.


1998 ◽  
Vol 25 (6) ◽  
pp. 409-411 ◽  
Author(s):  
Daisuke Sawamura ◽  
Tadashi Yaguchi ◽  
Isao Hashimoto ◽  
Kazuo Nomura ◽  
Ritsuko Konta ◽  
...  

2017 ◽  
Vol 1 (2) ◽  
pp. 91
Author(s):  
Samuel P Haslam ◽  
Lindy S Ross ◽  
Alison C Lowe ◽  
Brent C Kelly

Differentiating hypertrophic lichen planus (LP) from well-differentiated squamous cell carcinoma (SCC) is a histological challenge given the numerous histopathologic similarities between SCC and pseudoepitheliomatous hyperplasia (PEH) arising in the setting of hypertrophic LP. Multiple reports have shown that SCC can arise from hypertrophic LP not infrequently, but that the LP-to-SCC sequence is poorly understood, and many cases defy diagnosis due to histologic similarities. However, there are several clinical clues and histopathologic details that have shown to have some value when trying to ascertain the correct diagnosis. To the contrary, immunohistochemical tests have shown little promise in differentiating hypertrophic LP from SCC. Although multiplex PCR has shown some potential in differentiating PEH from SCC, this has only been in the setting of patients diagnosed with prurigo and lichen simplex chronicus, but not necessarily in the case hypertrophic LP. 


2021 ◽  
Vol 12 (e) ◽  
pp. e54-e54
Author(s):  
Singh Th. Nandakishore ◽  
Yaku Kago ◽  
Linda Kongbam ◽  
Romita Bachaspatimayum

Genital lichen planus (LP) forms a small but significant proportion of non-venereal genital dermatoses. Lesions of vulvovaginal LP are often asymptomatic and may be overlooked on self-examination. Clinical features are very similar to lichen sclerosus which is frequently seen in children whereas mucosal vulval LP commonly affects adult females. Histopathological examination of the lesion is an important diagnostic tool for its early diagnosis as progressive disease poses a risk of scarring. We report a case of vulvovaginal LP in a 56-year-old postmenopausal female presenting with hypopigmented patches on vulva for 10 years.


2017 ◽  
Vol 23 (6) ◽  
Author(s):  
Rafaella Cadore Olinger ◽  
Joseph Lucius Jorizzo ◽  
Felipe Bochnia Cerci

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