In vivo diffusion tensor imaging of the neonatal rat brain development

2013 ◽  
Vol 44 (S 01) ◽  
Author(s):  
M Breu ◽  
D Reisinger ◽  
D Wu ◽  
Y Zhang ◽  
A Fatemi ◽  
...  
2008 ◽  
Vol 86 (7) ◽  
pp. 1520-1528 ◽  
Author(s):  
K.H. Bockhorst ◽  
P.A. Narayana ◽  
R. Liu ◽  
P. Ahobila-Vijjula ◽  
J. Ramu ◽  
...  

2006 ◽  
Vol 24 (8) ◽  
pp. 483-483
Author(s):  
P. Narayana ◽  
K. Bockhorst ◽  
P. Ahobila ◽  
J. Ramu ◽  
J.R. Perez‐Polo

2019 ◽  
Vol 224 (5) ◽  
pp. 1815-1829 ◽  
Author(s):  
Markus Breu ◽  
Dominik Reisinger ◽  
Liangcheng Tao ◽  
Dan Wu ◽  
Yajing Zhang ◽  
...  

Neuroscience ◽  
2006 ◽  
Vol 137 (1) ◽  
pp. 145-155 ◽  
Author(s):  
D.L.A. Van den Hove ◽  
H.W.M. Steinbusch ◽  
A. Scheepens ◽  
W.D.J. Van de Berg ◽  
L.A.M. Kooiman ◽  
...  

1990 ◽  
Vol 267 (2) ◽  
pp. 561-564 ◽  
Author(s):  
B S Robinson ◽  
D W Johnson ◽  
A Poulos

Rat brain was recently found to contain polyenoic very-long-chain fatty acids (VLCFA) belonging to the n-3 and n-6 series with four, five and six double bonds and even-carbon chain lengths from 24 to 38 [Robinson, Johnson & Poulos (1990) Biochem. J. 265, 763-767]. In the present paper, the metabolism in vivo of hexacosatetraenoic acid (C26:4,n-6) was studied in neonatal rat brain. Rats were injected intracerebrally with [1-14C]C26:4,n-6 and the labelled metabolites were examined after 4 h. Radioactivity was detected mainly in non-esterified fatty acids, with smaller amounts in other neutral lipids and phospholipids. Radiolabelled fatty acid products included C28-36 tetraenoic and C26-28 pentaenoic VLCFA formed by elongation and desaturation of the substrate, and C14-24 saturated, C16-24 monoenoic, C18-24 dienoic, C18-22 trienoic and C20-24 tetraenoic fatty acids formed from released [1-14C]acetate either by synthesis de novo or by elongation of endogenous fatty acids. The data suggest that polyenoic VLCFA are synthesized in brain from shorter-chain precursor fatty acids and undergo beta-oxidation.


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