Rosmarinic acid content in antidiabetic aqueous extract of Ocimum canum Sims grown in Ghana

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
AO Affum ◽  
MA Berhow ◽  
BA Gyan
2012 ◽  
Vol 15 (7) ◽  
pp. 611-620 ◽  
Author(s):  
Mark A. Berhow ◽  
Andrews Obeng Affum ◽  
Ben A. Gyan

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
H Hajimehdipoor ◽  
M Shekarchi ◽  
S Saeidnia ◽  
A Gohari ◽  
Z Abedi

2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Shokoufe Nikpour Moghaddam ◽  
Durdi Qujeq ◽  
Ali Asghar Rastegari Efahani

2019 ◽  
Vol 120 ◽  
pp. 191-197 ◽  
Author(s):  
B. Asghari ◽  
S. Mafakheri ◽  
M.M. Zarrabi ◽  
S.A. Erdem ◽  
I.E. Orhan ◽  
...  

2019 ◽  
pp. 317-330
Author(s):  
Faruck Lukmanul Hakkim ◽  
Mohammad Idrees ◽  
Hamid A. Bakshi ◽  
Laiqahmed Mombasawala ◽  
Luay Rashan

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4183 ◽  
Author(s):  
Siti Hasyimah Suhaimi ◽  
Rosnani Hasham ◽  
Mohamad Khairul Hafiz Idris ◽  
Hassan Fahmi Ismail ◽  
Nor Hazwani Mohd Ariffin ◽  
...  

Primarily, optimization of ultrasonic-assisted extraction (UAE) conditions of Orthospihon stamineus was evaluated and verified using a central composite design (CCD) based on three factors including extraction time (minutes), ultrasound amplitude (A), and solvent concentration (%). The response surface methodology (RSM) was performed to develop an extraction method with maximum yield and high rosmarinic acid content. The optimal UAE conditions were as follows: extraction time 21 min, ultrasound amplitudes 62 A, and solvent composition 70% ethanol in water. The crude extract was further fractionated using solid-phase extraction (SPE), where six sequential fractions that varied in polarity (0–100% Acetonitrile in water) were obtained. Next, the six fractions were evaluated for their antioxidant and anti-cancer properties. This study found that Fraction 2 (F2) contained the highest rosmarinic acid content and showed the strongest antioxidant activity. Additionally, F2 showed an anti-proliferative effect against prostate cancer (DU145) with no harmful effect on normal cells.


2010 ◽  
Vol 58 (3) ◽  
pp. 191-195 ◽  
Author(s):  
Adolfina R. Koroch ◽  
Hector R. Juliani ◽  
Cedric Sims ◽  
James E. Simon

2013 ◽  
Vol 8 (4) ◽  
pp. 1934578X1300800
Author(s):  
Ivana Generalić Mekinić ◽  
Franko Burčul ◽  
Ivica Blaževieć ◽  
Danijela Skroza ◽  
Daniela Kerum ◽  
...  

The extracts obtained by 80% EtOH from some Asteraceae plants ( Calendula officinalis, Inula helenium, Arctium lappa, Artemisia absinthium and Achillea millefolium) were studied. Rosmarinic acid, one of the main compounds identified in all extracts, was determined quantitatively by using HPLC. In addition, spectrophotometric methods were evaluated as an alternative for rosmarinic acid content determination. Total phenolic content was also established for all extracts. A. millefolium extract was found to have the highest content of rosmarinic acid as well as total phenols. All extracts were tested for antioxidant and acetylcholinesterase inhibitory activity. A. millefolium was shown to possess the best antioxidant activity (for all tested methods) as well as acetylcholinesterase inhibitory activity. Highly positive linear relationships were obtained between antioxidant/acetylcholinesterase inhibitory activity and the determined rosmarinic acid content indicating its significance for the observed activities.


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